What is the Lifestar 404 Pill and What is its Purpose?
The Lifestar 404 pill is a 100 mg hard gelatin capsule containing nitrofurantoin, a urinary anti-infective antibiotic. It has an opaque gray cap and opaque brown body with 'Lifestar' on the cap and '404' on the body in white ink. This medication is used to treat acute, uncomplicated urinary tract infections (UTIs) in adults caused by susceptible bacteria such as Escherichia coli and Staphylococcus saprophyticus. Lifestar 404 is not effective for treating kidney infections (pyelonephritis) or perinephric abscesses as it primarily concentrates in the urinary tract.
Active Ingredients and Mechanism of Action
Each Lifestar 404 capsule contains a combination of 25 mg nitrofurantoin macrocrystals and 75 mg nitrofurantoin monohydrate. This formulation is designed for improved absorption and tolerance. The macrocrystals dissolve slower, while the monohydrate forms a gel matrix for sustained release in the gastrointestinal tract. Nitrofurantoin works by being reduced by bacterial enzymes into reactive molecules that damage multiple essential bacterial components, including DNA, RNA, proteins, and cell walls, leading to cell death. This broad action is thought to contribute to the limited development of bacterial resistance.
Important Drug Comparisons: Not All 404 Pills Are the Same
Correctly identifying medication by its unique markings, shape, and color is vital to avoid dangerous errors. There are other medications that include '404' in their imprint.
| Feature | Lifestar 404 Pill (Nitrofurantoin) | E 404 Pill (Amphetamine/Dextroamphetamine) | ADG 404 Pill (Carbinoxamine) |
|---|---|---|---|
| Appearance | Brown and gray, oblong capsule | Orange, round tablet | White, round tablet |
| Strength | 100 mg | 30 mg | 6 mg |
| Drug Class | Urinary anti-infective | CNS stimulant | Antihistamine |
| Primary Use | Uncomplicated urinary tract infections | ADHD, Narcolepsy | Allergic rhinitis and other allergic conditions |
| Controlled Substance? | No | Yes (Schedule II) | No |
| Manufacturer | Lifestar Pharma LLC | Sandoz Pharmaceuticals Inc. | Carwin Pharmaceutical Associates, LLC |
What to Expect While Taking Lifestar 404
Lifestar 404 should be taken with food to improve absorption and reduce nausea. Common side effects include nausea, headache, and flatulence. It is also normal for urine to turn brown. Patients must complete the full prescribed course of treatment to prevent antibiotic resistance and ensure the infection is cleared. Avoid antacids with magnesium trisilicate as they can reduce nitrofurantoin absorption.
Serious Side Effects and Precautions
Although uncommon, serious side effects can occur. These include lung reactions (like interstitial pneumonitis or pulmonary fibrosis) with symptoms such as fever, cough, and chest pain, especially with long-term use. Liver injury, though rare, can manifest as upper belly pain, dark urine, or jaundice. Peripheral neuropathy (nerve damage) is a risk, particularly in those with kidney issues, anemia, or diabetes, causing numbness or tingling. Clostridium difficile-associated diarrhea (CDAD) is also a possibility with antibiotic use.
Lifestar 404 is not suitable for patients with severe kidney problems, a history of liver issues from nitrofurantoin, or hypersensitivity to the drug. It is also contraindicated in pregnant patients near term, during labor/delivery, and in infants under one month due to the risk of hemolytic anemia. Always discuss your medical history with a healthcare provider before taking this medication.
Conclusion
The Lifestar 404 pill is a 100 mg nitrofurantoin capsule from Lifestar Pharma LLC for treating uncomplicated UTIs. Its brown and gray appearance distinguishes it from other medications with a '404' imprint. Proper identification, taking the medication with food, and being aware of potential side effects are crucial for safe and effective use under medical guidance.
For more detailed prescribing information and FDA labeling, refer to the DailyMed entry for Nitrofurantoin Capsules.
