What is a round pill with L 2 on it? An Imprint Identification Guide

October 8, 2025 •

4 min read

According to databases like Drugs.com, a simple imprint such as 'L 2' on a pill can correspond to several different medications, making additional characteristics crucial for correct identification. A round pill with L 2 on it could be an antidepressant, a thyroid medication, or an antipsychotic, depending on its specific details like color and dosage. Given the seriousness of these potential drugs, proper identification is essential.

Quick Summary

A round pill with the imprint L 2 is not a single medication and could indicate Trazodone, Liothyronine, Lurasidone, or others. Identification depends on factors like color and size. Always verify with a healthcare provider.

Key Points

Multiple Possibilities: A round pill with 'L 2' can be several different medications, including Trazodone, Liothyronine, Lurasidone, or Bupropion, depending on its specific characteristics.
Critical Identifying Factors: The pill's color and dosage are essential for correct identification, as the imprint 'L 2' alone is insufficient.
Trazodone Use: The white, round 50 mg pill with 'L 2' is Trazodone, an antidepressant used to treat depression, anxiety, and insomnia.
Lurasidone Use: A different white, round pill with 'L 2' (40 mg) is Lurasidone, an antipsychotic for bipolar disorder and schizophrenia.
Never Self-Identify: Relying on guesswork for pill identification is dangerous due to the risks of misidentification, incorrect dosage, and potential drug interactions.
Consult a Professional: The only safe way to confirm a pill's identity is to consult a pharmacist or doctor, who have access to comprehensive drug databases.
Potential Serious Effects: Misidentifying a pill could lead to severe health consequences due to the potent and specific nature of these medications.

Understanding the 'L 2' Imprint: Multiple Possibilities

When you encounter an unmarked pill, finding its exact identity is a critical step for your health and safety. The imprint 'L 2' is not unique to a single drug. The color, shape, and size of the pill are all essential pieces of information for accurate identification. A professional pill identification tool or consultation with a pharmacist is the safest way to confirm a medication.

Potential Match: Trazodone Hydrochloride

A common medication that matches the description is a 50 mg tablet of Trazodone Hydrochloride. As an antidepressant, Trazodone works by altering levels of serotonin, a naturally occurring substance in the brain.

Appearance: White, round pill with 'L 2' imprinted on one side.
Manufacturer: Granules Pharmaceuticals Inc..
Therapeutic Class: Phenylpiperazine antidepressants.
Common Uses: Major depressive disorder, anxiety, and insomnia.

Potential Match: Liothyronine Sodium

Another possibility for a white, round pill with 'L 2' is Liothyronine Sodium, a thyroid medication. This synthetic form of the thyroid hormone T3 is used to treat conditions of the thyroid gland.

Appearance: White, round pill with 'L 2' imprint.
Dosage: 25 mcg.
Therapeutic Class: Thyroid drugs.
Common Uses: Hypothyroidism (underactive thyroid) and thyroid suppression tests.

Potential Match: Lurasidone Hydrochloride

A white, round pill with 'L 2' could also be Lurasidone Hydrochloride. This is an atypical antipsychotic medication with distinct uses and potential side effects.

Appearance: White, round pill with 'L 2' imprint.
Dosage: 40 mg.
Manufacturer: Camber Pharmaceuticals, Inc..
Therapeutic Class: Atypical antipsychotics.
Common Uses: Bipolar disorder and schizophrenia.

Potential Match: Bupropion Hydrochloride Extended-Release (XL)

Some pill identifiers show a white, round pill with the imprint 'L2' (no space) as Bupropion Hydrochloride Extended-Release. This antidepressant is also used for smoking cessation.

Appearance: White, round pill with 'L2' imprint.
Dosage: 150 mg.
Therapeutic Class: Miscellaneous antidepressants, smoking cessation agents.
Common Uses: Major depressive disorder, seasonal affective disorder, and smoking cessation.

Important Considerations for Safe Medication Practices

Identifying a pill using an imprint is just the first step. Never assume you know what a medication is without professional confirmation. Potential dangers of misidentification include serious side effects, drug interactions, or failing to treat an underlying condition effectively.

Here are some of the critical side effects and warnings associated with these potential drugs:

Trazodone:

Common Side Effects: Drowsiness, dry mouth, dizziness, blurred vision.
Serious Warnings: Risk of suicidal thoughts, serotonin syndrome (especially when combined with other drugs), and heart rhythm problems.

Liothyronine Sodium:

Common Side Effects: Noted in studies as being primarily related to dose adjustments, requiring careful monitoring.
Serious Warnings: Heart rhythm problems, risk of worsening certain heart conditions.

Lurasidone Hydrochloride:

Common Side Effects: Drowsiness, nausea, restlessness (akathisia), movement problems.
Serious Warnings: Increased risk of suicidal thoughts in younger adults, neuroleptic malignant syndrome, and tardive dyskinesia.

Bupropion XL:

Common Side Effects: Dry mouth, nausea, constipation, trouble sleeping.
Serious Warnings: Risk of seizures, especially with higher doses or certain medical conditions, and increased risk of suicidal thoughts.

Comparison Table: Round Pills with 'L 2' or 'L2'


Imprint	Color	Shape	Active Ingredient	Dosage	Common Uses	Drug Class	Manufacturer
L 2	White	Round	Trazodone HCl	50 mg	Depression, Anxiety, Insomnia	Antidepressant	Granules Pharma
L 2	White	Round	Liothyronine Sodium	25 mcg	Hypothyroidism, Thyroid Suppression	Thyroid drug	Biocon Pharma
L 2	White	Round	Lurasidone HCl	40 mg	Bipolar Disorder, Schizophrenia	Antipsychotic	Camber Pharma
L2	White	Round	Bupropion HCl ER	150 mg	Depression, Smoking Cessation	Antidepressant	Various (e.g., Sun Pharma)
L2	Yellow	Round	Methotrexate Sodium	2.5 mg	Arthritis, Psoriasis, Leukemia	Immunosuppressant	Zydus Pharma

The Critical Role of Professional Verification

Because of the various possibilities associated with an 'L 2' imprint, professional verification is non-negotiable. Pharmacists and doctors can use their resources and knowledge to correctly identify a medication based on its appearance, packaging, and your personal medical history. The risk of mistaking a potent antipsychotic for an antidepressant, or vice versa, is too high to rely solely on online searches. The most important message is to exercise caution and consult a professional immediately if you are unsure of a pill's identity. If you or someone you know has taken a pill of unknown origin and is experiencing adverse effects, seek emergency medical attention.

Your Safe Practice Checklist

Do not take an unknown pill: If you find a pill you don't recognize, do not take it. A single dose of the wrong medication could be harmful.
Keep all medications in their original containers: This prevents mixing and confusion, ensuring the label and prescription details are always available.
Consult a pharmacist: If you have a question about a pill, take it to a pharmacist. They can use professional databases to identify it and answer your questions safely.
Talk to your doctor: If you have questions about your prescription or are unsure about your medication, contact your doctor for clarification.
Use reliable online tools with caution: Pill identifier tools can be helpful but should only be used as a starting point. Final confirmation must come from a healthcare professional.

For more information on pill identification and medication safety, consult trusted resources such as the Drugs.com Pill Identifier. Remember, your health is paramount, and safe medication practices are key to preventing harm.

Frequently Asked Questions

No, a white round pill with L 2 is not always Trazodone. While a 50 mg Trazodone tablet can match this description, other medications like Liothyronine (25 mcg) and Lurasidone (40 mg) can also be white and round with the 'L 2' imprint.

Both Trazodone and Lurasidone can be white and round with the 'L 2' imprint, but they have different dosages (50 mg vs 40 mg). A pharmacist can definitively distinguish between them and confirm the active ingredient and manufacturer.

The presence or absence of a space between the 'L' and the '2' can be significant for identification. For example, a white, round pill with 'L2' (no space) could be 150 mg of Bupropion XL, while 'L 2' typically indicates a different set of medications like Trazodone or Lurasidone.

Depending on the specific medication, a pill with 'L 2' can have very different uses. For instance, Trazodone is for depression and anxiety, Liothyronine treats an underactive thyroid, and Lurasidone is an antipsychotic for conditions like bipolar disorder.

No, you should never take a pill if you are unsure of its identity. The different medications associated with this imprint have vastly different uses, dosages, and side effects. Taking the wrong medication could be harmful or life-threatening.

If you find an unidentified pill, do not take it. The safest course of action is to take it to a pharmacist for identification. They can examine the pill's features and use professional resources to provide a definitive match.

A pharmacist can use the imprint as a key piece of information, but they will also need to consider the pill's color, shape, and potentially its size. Combined, these details allow for a much more accurate identification, though confirmation of the original prescription is ideal.

Yes, other pill forms can have similar imprints. For example, a green, oval pill with 'L 2' is Loperamide Hydrochloride, an antidiarrheal medication.