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What is Amelan cream used for?

4 min read

Originally developed by plastic surgeon Dr. Eduardo Krulig, Amelan is a depigmentation system that has been used by dermatologists for decades to address various forms of skin blemishes. So, what is Amelan cream used for? Primarily, it is an intensive treatment for hyperpigmentation, including melasma, sun spots, and post-inflammatory pigmentation.

Quick Summary

Amelan cream is a powerful topical treatment for hyperpigmentation, effectively reducing melasma, dark spots, and uneven skin tone by inhibiting melanin production. The system often involves a professional application followed by a dedicated at-home regimen to deliver optimal results.

Key Points

  • Hyperpigmentation Treatment: Amelan cream is primarily used to treat hyperpigmentation, including melasma, sun spots, and post-inflammatory hyperpigmentation.

  • Blocks Melanin Production: The cream works by inhibiting the enzyme tyrosinase, blocking oxidation, and interfering with melanin transfer to lighten dark spots.

  • Professional System: Amelan is part of a professional treatment system that combines an in-clinic mask application with a long-term at-home cream regimen.

  • Multiple Active Ingredients: Its powerful formulation includes key lightening agents like Kojic Acid, Alpha-Arbutin, Vitamin C, and Phytic Acid.

  • Expected Side Effects: Initial side effects include redness, peeling, and dryness, which are normal parts of the skin renewal process and managed with proper aftercare.

  • Requires Sun Protection: Continuous and rigorous sun protection is a mandatory part of the treatment to prevent re-pigmentation and protect healing skin.

  • Not an OTC Product: The Amelan treatment requires application and supervision by a qualified dermatologist to ensure safe and effective results.

In This Article

What is Amelan Cream Used For?

Amelan cream is a key component of a professional depigmentation system designed to combat skin blemishes and promote a more even skin tone. It is most prominently used to treat stubborn hyperpigmentation issues that may not respond to standard cosmetic treatments. The indications for Amelan treatment include:

  • Melasma: Specifically, cases of melasma induced by hormonal changes, such as during pregnancy (chloasma) or due to contraceptive use.
  • Solar and Senile Lentigo: Commonly known as sun spots or age spots, which result from sun exposure.
  • Post-Inflammatory Hyperpigmentation (PIH): Dark spots that appear on the skin following an inflammatory event, such as acne, burns, or trauma.
  • Photoaging and Photo-damage: General signs of skin aging caused by sun exposure.
  • Prevention: In some cases, it can be used to prevent the formation of dark spots in skin types that are predisposed to pigmentation problems.

Mechanism of Action

Amelan cream works through a multi-faceted approach to inhibit the process of melanogenesis—the production of melanin pigment in the skin. Its active ingredients intervene at several key points:

  • Tyrosinase Inhibition: The formula contains ingredients, such as Kojic acid and Vitamin C, that block the action of tyrosinase, an enzyme critical for melanin synthesis.
  • Oxidation Inhibition: It contains antioxidants that prevent the oxidation process necessary for melanin formation.
  • Melanin Transfer Interference: Amelan interferes with the transfer of melanin from melanocytes (the pigment-producing cells) to keratinocytes (the skin's surface cells). By halting this transfer, it prevents the pigment from reaching the upper layers of the epidermis where it becomes visible.

This combined mechanism ensures a powerful and effective reduction of hyperpigmentation.

Key Active Ingredients

Amelan cream's efficacy is due to its potent blend of active ingredients, which can vary slightly depending on the specific product formulation (e.g., from different labs) but generally include a combination of:

  • Alpha-Arbutin: A gentle yet effective skin-lightening agent.
  • Kojic Acid: A well-known tyrosinase inhibitor.
  • Phytic Acid: A natural antioxidant that also contributes to depigmentation.
  • Retinol Palmitate: A form of Vitamin A that helps renew the skin's surface.
  • Vitamin C (Ascorbic Acid): A potent antioxidant that brightens the skin and inhibits melanin.
  • LUMISKIN™ (Diacetyl Boldine): A skin-brightening complex derived from the Boldo tree.

Amelan vs. Other Depigmenting Treatments

Feature Amelan Cream Cosmelan / Dermamelan Standard Hydroquinone Cream
Application Typically part of a multi-step professional system with at-home cream application. Professional in-clinic mask application followed by a detailed at-home regimen. Can be prescribed for at-home use without an initial mask application.
Active Ingredients Formulated with non-hydroquinone agents like Kojic Acid, Arbutin, Vitamin C, and Phytic Acid. Also non-hydroquinone; formulations are generally more concentrated and intensive. Contains hydroquinone, a strong and regulated bleaching agent.
Intensity Medium-depth peel system with powerful depigmenting action, offering significant results. Stronger and more intensive, particularly the Dermamelan version, for more severe cases. Intensity depends on the concentration; prolonged use can have side effects.
Mechanism Inhibits tyrosinase, oxidation, and melanin transfer. Also inhibits tyrosinase but is known for high efficacy in targeting melanin synthesis. Acts as a potent tyrosinase inhibitor.
Downtime Expected flaking and redness, especially during the initial phase. Can cause more pronounced redness, tightness, and peeling, especially in the first week. May cause mild irritation and dryness; severe irritation is a potential side effect.

The Amelan Treatment Protocol and What to Expect

The Amelan process generally begins with a professional application of a depigmenting mask in a clinical setting. The protocol includes a crucial at-home maintenance phase using Amelan cream. The dermatologist will provide specific instructions, but a typical regimen involves:

  • In-Clinic Phase: A professional applies the Amelan mask, which remains on the skin for a few hours.
  • At-Home Phase: The client follows up with daily application of the Amelan cream, often twice a day initially, for a specified period of several months.
  • Post-Treatment Care: During the initial week, the skin will likely experience redness, tightness, and flaking. It is crucial to use gentle, recommended moisturizers and apply high-SPF sunscreen daily to protect the new skin.

Conclusion

Amelan cream serves as a highly effective, professional-grade solution for persistent hyperpigmentation issues such as melasma, sun spots, and post-inflammatory hyperpigmentation. Its comprehensive mechanism of action, which targets multiple stages of melanin production, results in a more uniform and brighter complexion. While it requires a commitment to a detailed treatment protocol and diligent post-care, it offers a powerful option for individuals seeking significant improvement in skin tone. To achieve the best and safest outcome, the treatment must be administered and overseen by a qualified dermatologist.

For more detailed information on specific formulations, consulting the official website of the originating laboratory can provide further insight. Krulig Laboratorios

Side Effects of Amelan Treatment

Following Amelan treatment, it is normal to experience side effects, particularly during the initial peeling phase. Common reactions include:

  • Skin redness or erythema.
  • Skin tightness and a feeling of swelling.
  • Flaking and peeling, similar to a sunburn.
  • Mild burning or stinging sensation.
  • Dryness.

These effects are typically temporary and subside as the skin heals. Proper post-treatment care, including frequent moisturizing and sun protection, is essential to minimize discomfort.

Importance of Professional Oversight

Because Amelan is a potent dermatological treatment, it is not available over the counter and requires professional supervision. A dermatologist can correctly diagnose the type and severity of hyperpigmentation, determine suitability for the treatment, and manage potential side effects. Individuals with certain allergies (e.g., to aspirin) or skin conditions like eczema or psoriasis should avoid this treatment.

Frequently Asked Questions

Many people see a significant improvement in skin tone and a reduction in dark spots within 8 days of starting the treatment. The full benefits are realized over several weeks or months of consistent use as part of the home care regimen.

No, Amelan treatment is not recommended for pregnant or lactating women due to its potent ingredients. It's crucial to consult a dermatologist for safe alternatives.

No, they are not the same, though Dermamelan was formerly known as Amelan. Dermamelan is generally considered a more intensive and concentrated treatment for severe pigmentation issues, while Amelan serves as a powerful option for medium-depth depigmentation.

Aftercare involves using gentle, hydrating cleansers and moisturizers, and avoiding sun exposure by regularly applying a high-SPF sunscreen. It's also important to avoid hot water and strenuous exercise for a few days post-treatment.

During the first week of treatment, it is normal to experience some skin flaking and peeling, similar to a sunburn. This is part of the exfoliation process and will subside.

The professional application and at-home regimen are tailored to the individual, and Amelan can be compatible with all skin types. However, a dermatologist will assess suitability and risk of irritation during the consultation.

Amelan and Cosmelan are both professional depigmentation systems with similar mechanisms. Amelan by Krulig is an older, well-established system, while Cosmelan is also a popular brand, with Dermamelan being its more intensive variant.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.