Desogestrel is a synthetic progestin commonly used in hormonal contraception, classified as a third-generation progestin. It is available as a progestin-only pill (POP) and in combination oral contraceptives (COC) with ethinyl estradiol.
Brand names for desogestrel
Desogestrel is known by various brand names depending on its formulation and location. Cerazette is a well-known progestin-only mini-pill used outside the U.S.. In the U.S., desogestrel is more often found in combination pills. Some notable brand names include:
- Cerazette: A progestin-only mini-pill, prominent in the UK and Europe.
- Cerelle: A generic mini-pill containing desogestrel.
- Desogen (discontinued): An original combination pill with ethinyl estradiol, now available as generics.
- Apri: A generic combination pill (desogestrel/ethinyl estradiol).
- Enskyce: Another generic equivalent for the desogestrel/ethinyl estradiol combination.
- Isibloom: Also a generic combination pill.
- Kariva: A brand of biphasic combination pill.
- Viorele: Another biphasic combination brand.
- Mircette: Includes desogestrel with two different doses of ethinyl estradiol.
- Marvelon: A recognized combined oral contraceptive containing desogestrel, often used outside the U.S..
How desogestrel works
Desogestrel prevents pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining. Its effectiveness is influenced by whether it's a POP or COC. The active metabolite is etonogestrel, which is responsible for the progestational effects.
Comparison of desogestrel formulations
The key difference in desogestrel products is the presence or absence of ethinyl estradiol.
| Feature | Progestin-Only Pills (e.g., Cerazette, Cerelle) | Combination Oral Contraceptives (e.g., Apri, Enskyce) |
|---|---|---|
| Hormones | Desogestrel only | Desogestrel and Ethinyl Estradiol |
| Mechanism | Primarily prevents ovulation; thickens cervical mucus. | Inhibits ovulation; thickens cervical mucus; alters uterine lining. |
| Dosing | Continuous daily dosing, without a break. | Typically 21 active pills followed by 7 inactive pills. |
| Missed Pill | 12-hour window for missed doses, more forgiving than older mini-pills. | Specific instructions apply; efficacy may be reduced if active pills are missed. |
| Side Effects | Can include irregular bleeding, spotting, and mood changes. | Potential for nausea, headaches, and breast tenderness. Some data suggests a slightly higher blood clot risk compared to older progestins. |
| User Profile | Suitable for those who cannot use estrogen. | Appropriate for many women, but not those with a history of blood clots or severe hypertension. |
Therapeutic and non-contraceptive uses
Desogestrel is primarily a contraceptive but may be used off-label for conditions like endometriosis by suppressing endometrial tissue. It can also lead to reduced or absent periods, which can help manage heavy bleeding.
Conclusion
Desogestrel is a synthetic progestin found under various brand and generic names, including progestin-only options like Cerazette and combined pills such as Apri and Kariva. Recognizing these different names is important for proper use of this effective contraceptive. For more detailed information, consult {Link: DrOracle.ai https://www.droracle.ai/articles/198738/names-of-oral-contraceptives-containing-desogestrel}.
