The generic name for Valtoco
Valtoco is the brand name for diazepam nasal spray. Its active ingredient is diazepam, which is the generic name. Diazepam is a benzodiazepine that works by increasing the effect of GABA in the brain, helping to reduce the nerve activity that causes seizures. Valtoco is specifically designed for the quick treatment of seizure clusters or acute repetitive seizures. Its nasal spray delivery is intended to be a more convenient and ready-to-use alternative to older methods like rectal gel. The FDA has acknowledged the clinical superiority of the nasal spray formulation for patient care.
Comparison of different diazepam formulations
Diazepam comes in several forms besides Valtoco. A notable comparison is with Diastat, the diazepam rectal gel. The table below highlights key differences between Valtoco and Diastat:
| Feature | Valtoco (Diazepam Nasal Spray) | Diastat (Diazepam Rectal Gel) |
|---|---|---|
| Active Ingredient | Diazepam | Diazepam |
| Route of Administration | Intranasal (into the nose) | Rectal (into the rectum) |
| Ease of Use | Considered easier and more dignified to administer by both patients and caregivers. | Can be awkward or embarrassing, especially for older patients or in public settings. |
| Absorption | Made with Intravail® technology for enhanced and rapid absorption through the nasal mucosa. | Absorption can have more variability compared to the intranasal route. |
| Age Indication | Approved for patients 2 years of age and older. | Approved for patients 2 years of age and older. |
| Preparation | No priming required; each single-use device is ready to spray. | Requires a bit more preparation and assembly. |
Using Valtoco for seizure clusters
Valtoco is an emergency rescue therapy for seizure clusters and is not for preventing seizures daily. It's used when a patient experiences a seizure pattern different from their usual. Following a healthcare provider's Seizure Action Plan is crucial for proper administration.
- Administration steps:
- Hold the device with your thumb on the plunger and your fingers on the nozzle. Do not prime.
- Insert the tip into one nostril. Some doses require a second device in the other nostril.
- Press the plunger firmly.
- Dosage considerations: Dosage depends on age and weight and may change over time.
- Frequency limits: Do not use more often than once every 5 days or more than 5 times a month to avoid dependence.
Important safety information and side effects
Valtoco, like other benzodiazepines, has safety warnings and potential side effects. Common side effects include drowsiness, headache, and nasal discomfort.
Key warnings include:
- Opioid use: Combining Valtoco with opioids can cause severe sedation, respiratory issues, coma, and death. Always inform your doctor about all medications.
- Abuse and dependence: Valtoco is a Schedule IV controlled substance due to potential for abuse. It's not for daily use, and stopping it abruptly after frequent use can cause severe withdrawal.
- CNS depression: It can cause drowsiness and affect motor skills. Be cautious when driving or using machinery.
- Suicidal thoughts: All antiepileptic drugs, including Valtoco, may increase the risk of suicidal thoughts. Monitor for mood changes.
Conclusion
Valtoco is the brand name for diazepam nasal spray, a rescue medication for seizure clusters. Its generic active ingredient is diazepam, also found in products like Diastat rectal gel and Valium oral tablets. Valtoco offers a faster-acting, more convenient intranasal delivery method for managing acute seizures outside a hospital. For more detailed information, consult the official Prescribing Information document {Link: valtoco.com https://valtoco.com/VALTOCO_Prescribing_Information.pdf}.
