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What is better for hemorrhoids: Preparation H or ANUSOL? A Detailed Comparison

4 min read

Roughly half of all people over 50 will experience hemorrhoid symptoms at some point, making over-the-counter treatments a common solution. When faced with the discomfort of hemorrhoids, many wonder: what is better for hemorrhoids, Preparation H or ANUSOL? The answer lies in their different active ingredients and how they target specific symptoms like swelling, itching, and pain.

Quick Summary

This comparison details the different active ingredients and mechanisms of action for common over-the-counter Preparation H and ANUSOL products. It explores how each brand targets specific hemorrhoid symptoms, from swelling and inflammation to itching and pain, to help consumers choose the most suitable treatment for their needs.

Key Points

  • Symptom-Specific Ingredients: Preparation H uses phenylephrine to shrink swollen tissue, while OTC ANUSOL uses zinc oxide as a protective barrier and pramoxine as a topical anesthetic.

  • Numbing for Pain: If pain and itching are the primary concern, both brands offer products with a numbing agent like pramoxine for temporary relief.

  • Inflammation Management: For intense itching or inflammation, a hydrocortisone-containing cream can be used short-term, but note that prescription Anusol-HC contains a higher concentration.

  • Formulation Options: Both brands are available in various forms, including creams, ointments, and suppositories, to treat both internal and external hemorrhoids.

  • Usage Precautions: Always check for potential drug interactions and consult a doctor if symptoms persist after a week, as other conditions could be the cause.

In This Article

Understanding the Active Ingredients in Hemorrhoid Treatments

Over-the-counter (OTC) hemorrhoid products like Preparation H and ANUSOL are formulated with different active ingredients to target specific symptoms. The right choice depends heavily on which symptom is causing the most distress, as one product may be better for shrinking swollen tissue while another is more effective for numbing pain or creating a protective barrier.

Preparation H: Shrinking and Numbing

Many standard Preparation H products contain phenylephrine HCl, a vasoconstrictor that works to shrink swollen hemorrhoidal blood vessels. This effect helps reduce swelling and the associated discomfort. In addition, many multi-symptom Preparation H formulas include pramoxine HCl, a local anesthetic that provides temporary relief from pain and itching. Other Preparation H products, like the hydrocortisone anti-itch cream, specifically target itching and inflammation with a topical steroid.

ANUSOL: Protection and Anesthesia

Over-the-counter ANUSOL products typically rely on different active ingredients. For example, some contain zinc oxide, a skin protectant that forms a barrier over the skin to soothe and protect irritated areas. Other versions, such as Anusol Plus, incorporate pramoxine hydrochloride to provide a numbing effect for pain and itching relief. It's crucial to note the distinction with the prescription-only ANUSOL-HC, which contains hydrocortisone to reduce inflammation and requires a doctor's supervision.

Comparison of Preparation H and ANUSOL

The following table outlines the differences between standard over-the-counter formulations of these two popular hemorrhoid treatments.

Feature Common OTC Preparation H Common OTC ANUSOL (e.g., Plus)
Primary Action Vasoconstrictor (shrinks blood vessels) Skin Protectant, Anesthetic
Key Active Ingredients Phenylephrine HCl (vasoconstrictor), Pramoxine HCl (anesthetic), Petrolatum (protectant) Zinc Oxide (protectant), Pramoxine HCl (anesthetic)
Best For Symptoms Swelling, itching, and minor pain. Best when the primary issue is a swollen hemorrhoid. Itching, burning, pain, and protecting irritated skin.
Formulations Ointment, cream, suppositories, gel, and medicated wipes Ointment, cream, suppositories
Drug Interactions Potential interactions with certain medications, including some for high blood pressure. Fewer documented drug interactions for standard OTC versions.
Considerations Not for individuals with certain medical conditions like high blood pressure or diabetes unless directed by a doctor. Generally well-tolerated, focusing on soothing and protective effects.

Choosing the Right Product for Your Symptoms

To decide what is better for hemorrhoids, Preparation H or ANUSOL, consider the most bothersome symptom:

  • For swelling and shrinking: If a primary concern is reducing the size of swollen hemorrhoidal tissue, a Preparation H product with phenylephrine is the more direct solution.
  • For pain and itching: If the main issue is pain, burning, or intense itching, look for an anesthetic. Both brands offer products with pramoxine for numbing relief. For particularly stubborn itching, a hydrocortisone cream (available OTC, including from Preparation H, or as a prescription like Anusol-HC) may be more effective, but should be used for a limited duration.
  • For protection and soothing: If the goal is to protect the area from further irritation and to soothe burning sensations, an ANUSOL product with a protective ingredient like zinc oxide is a good choice.

Important Usage Considerations

Regardless of which product you choose, proper usage is essential for effectiveness and safety. Always read the package directions carefully. For ointments and creams, clean and dry the affected area gently before application. Suppositories are designed for internal hemorrhoids and should be inserted as directed.

Key best practices include:

  • Use products only as directed and for the specified duration. Overuse, especially of hydrocortisone-containing products, can lead to side effects like thinning skin.
  • Consider using gentle cleansing methods, such as medicated wipes with witch hazel, instead of rough toilet paper to avoid further irritation.
  • Enhance treatment effectiveness with supportive measures, such as taking sitz baths with warm water several times a day to soothe the area.

When to Consult a Doctor

While OTC treatments can be highly effective for minor hemorrhoid symptoms, they are not a cure-all. You should consult a healthcare provider in the following circumstances:

  • Symptoms do not improve after a week of using an OTC product.
  • Experiencing significant or persistent rectal bleeding.
  • Severe pain or worsening symptoms occur.
  • Suspected side effects, such as a severe allergic reaction, occur.
  • You have internal hemorrhoids and require medication for them specifically.
  • You have other medical conditions like heart disease or high blood pressure that may be affected by certain ingredients.

Conclusion

Ultimately, there is no single best answer to whether Preparation H or ANUSOL is superior for hemorrhoids, as the optimal choice depends on the specific symptoms being treated. Preparation H is often preferred for shrinking swollen tissue, while OTC ANUSOL provides effective protective and anesthetic relief. By understanding the active ingredients and how they work, consumers can make an informed decision based on their individual needs. For persistent or severe symptoms, consulting a healthcare professional is always the best course of action. For more information on supportive care and other options, you can read more on the Walgreens blog.

Frequently Asked Questions

Preparation H products that contain phenylephrine are specifically formulated to act as a vasoconstrictor, which helps to shrink swollen hemorrhoidal tissues.

For numbing pain and itching, products containing a local anesthetic like pramoxine are effective. Both Preparation H and OTC ANUSOL (such as Anusol Plus) offer formulations with pramoxine for this purpose.

No, Anusol-HC is a prescription-only product that contains the powerful anti-inflammatory steroid hydrocortisone. This is different from the standard over-the-counter ANUSOL products, which typically use protectants and milder anesthetics.

Yes, potential side effects for Preparation H (phenylephrine) can include allergic reactions or, in rare cases, increased blood pressure. For hydrocortisone products, prolonged use can lead to skin thinning. It's crucial to follow instructions and consult a doctor for serious side effects.

You should not use different hemorrhoid creams or ointments at the same time unless directed by a healthcare professional. Overlapping ingredients could increase the risk of side effects or diminish the effectiveness of one product.

For internal hemorrhoids, suppositories are generally most effective because they deliver medication directly to the internal lining of the rectum. Both Preparation H and ANUSOL offer suppositories.

You should stop using the product and see a doctor if your symptoms do not improve after about a week, if you experience rectal bleeding, or if your symptoms worsen. A professional diagnosis is necessary for persistent issues.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.