What is Gatiquin P Used For? A Comprehensive Guide

October 7, 2025 •

3 min read

Acute endophthalmitis is a severe complication following cataract surgery, with an incidence rate of 0.04% to 0.099% in developed nations. Combination medications are often prescribed post-surgery to manage inflammation and prevent infection. This article answers, 'What is Gatiquin P used for?'

Quick Summary

Gatiquin P is a prescription eye drop containing Gatifloxacin and Prednisolone. It is used to treat bacterial eye infections and to manage inflammation, swelling, and pain, particularly after eye surgery.

Key Points

Dual-Action Formula: Gatiquin P combines Gatifloxacin (an antibiotic) and Prednisolone (a corticosteroid).
Primary Use: It treats bacterial eye infections and reduces associated inflammation, pain, and swelling.
Post-Surgical Care: It is commonly prescribed after eye surgeries, like cataract removal, to prevent infection and manage inflammation.
Mechanism: Gatifloxacin kills bacteria by inhibiting their DNA replication, while Prednisolone blocks inflammatory responses.
Administration: Used as a topical eye drop, it's crucial to follow dosage instructions and not to touch the dropper to any surface.
Contraindications: This medication should not be used for viral or fungal eye infections.
Precautions: Prolonged use can increase the risk of glaucoma or cataracts; always use as prescribed by a doctor.

What is Gatiquin P?

Gatiquin P is a combination ophthalmic solution used for treating bacterial eye infections and associated inflammation. It is often prescribed when both an antibiotic and an anti-inflammatory are needed, such as after eye surgeries like cataract surgery. This combination aims to simplify treatment and improve patient adherence. It is for topical use in the eye only.

The Dual-Action Mechanism: How Gatiquin P Works

Gatiquin P contains two main active ingredients: Gatifloxacin and Prednisolone.

Gatifloxacin: This is a fourth-generation fluoroquinolone antibiotic. It kills bacteria by stopping essential enzymes needed for DNA replication and repair. It is effective against various bacteria that cause eye infections.
Prednisolone: This is a strong corticosteroid that reduces inflammation. It works by blocking chemicals that cause redness, swelling, and itching, helping to alleviate discomfort and protect the eye.

Primary Uses and Indications

Healthcare providers may prescribe Gatiquin P for several eye conditions involving bacterial infection and inflammation.

Post-Operative Inflammation and Infection Prevention: A common use is to reduce pain and swelling after eye surgeries, such as cataract surgery, while preventing bacterial infections.
Bacterial Conjunctivitis: Gatiquin P treats this bacterial infection of the outer eye layer and reduces inflammatory symptoms.
Other Inflammatory Ocular Conditions: It is also used for inflammatory conditions of the conjunctiva, cornea, and front part of the eye when there's a risk of bacterial infection. This can include conditions like eyelid inflammation (blepharitis) and corneal ulcers.

How to Use Gatiquin P Eye Drops Correctly

Follow your doctor's instructions for using Gatiquin P. General steps for application include:

Wash your hands before use.
Check the bottle's seal and avoid touching the dropper tip.
Tilt your head back, pull down the lower eyelid to form a pocket.
Squeeze the dropper to place drops in the pocket.
Close your eye for a few minutes or gently press the inner corner to prevent drainage.
If using other eye drops, wait 5-10 minutes between applications.

Side Effects and Precautions

Common Side Effects: Side effects are usually temporary and affect the eye. These may include:

Mild irritation, burning, or stinging
Temporary blurred vision
Watery eyes
Eye discomfort or itching
A bad taste

Important Precautions:

Avoid use if allergic to Gatifloxacin, Prednisolone, other quinolone antibiotics, or any ingredients.
Do not wear contact lenses during an eye infection. If allowed by your doctor, remove lenses before using the drops and wait 15 minutes before reinserting.
Not suitable for viral or fungal eye infections like herpes simplex keratitis.
Long-term use of corticosteroids can lead to glaucoma or cataracts; use only as prescribed.
Avoid driving or operating machinery if you experience temporary blurred vision.

Comparison Table: Combination vs. Separate Components


Feature	Gatiquin P (Fixed Combination)	Gatifloxacin + Prednisolone (Separate Drops)
Convenience	High: Single application.	Lower: Two separate applications with waiting.
Efficacy	Comparable to separate use for post-operative care.	Effective as individual treatments.
Preservative Load	Potentially lower.	Higher from two solutions.
Cost	May be more cost-effective.	Depends on individual drug pricing.
Patient Compliance	Generally higher.	May be lower.

Conclusion

Gatiquin P is a combination medication effectively treating bacterial eye infections with inflammation. Its components, Gatifloxacin and Prednisolone, work together to eliminate infection and reduce symptoms. It is frequently used after eye surgery to promote recovery and prevent issues. Always use Gatiquin P as directed by a healthcare professional for safe and effective treatment.

For more information on the components of Gatiquin P, you can visit the CiplaMed product page.

Frequently Asked Questions

Gatiquin P is used to treat bacterial eye infections and to reduce associated inflammation such as pain, redness, and swelling, especially after eye surgery.

The active ingredients in Gatiquin P are Gatifloxacin, which is an antibiotic, and Prednisolone, which is a corticosteroid.

No, it is generally advised not to wear contact lenses while you have an active eye infection or while using Gatiquin P. If your doctor approves, you should remove your lenses before applying the drops and wait at least 15 minutes before reinserting them.

Common side effects are usually temporary and may include mild eye irritation, a burning or stinging sensation, temporary blurred vision, and watery eyes.

Gatiquin P has a dual-action mechanism. The Gatifloxacin component kills the bacteria causing the infection, while the Prednisolone component, a steroid, reduces the inflammation, swelling, and redness caused by the infection.

Gatiquin P is a combination medication that contains a steroid. Prednisolone is a corticosteroid, while the other active ingredient, Gatifloxacin, is an antibiotic.

You should use Gatiquin P for the exact duration prescribed by your doctor. It is important to complete the full course to prevent the infection from returning, but prolonged use should be avoided unless directed by a doctor due to risks associated with long-term steroid use.