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What is in Vicks that kills fungus? A look at the science behind the home remedy

4 min read

According to a 2011 study published in the Journal of the American Board of Family Medicine, 15 out of 18 participants with toenail fungus saw positive results after using Vicks VapoRub, leading many to wonder what is in Vicks that kills fungus. While not an FDA-approved treatment, the active ingredients in this common ointment are known for their mild antifungal properties.

Quick Summary

Vicks VapoRub contains active ingredients like camphor, menthol, and eucalyptus oil, which possess mild antifungal properties and are responsible for its potential effects against certain fungi. Scientific evidence is limited, and Vicks is not a medically validated treatment for onychomycosis, so effectiveness and complete cures are not guaranteed.

Key Points

  • Antifungal Ingredients: The primary active ingredients with potential antifungal properties in Vicks are camphor, eucalyptus oil, and menthol.

  • Limited Evidence: Scientific support for Vicks's effectiveness against toenail fungus comes from a single, small 2011 study with a low cure rate.

  • Not FDA-Approved: Vicks VapoRub is not an FDA-approved antifungal treatment and should not be considered a substitute for professional medical care.

  • Mechanism of Action: The volatile compounds in Vicks may disrupt fungal cell membranes and create an inhospitable, oxygen-poor environment for the fungus.

  • Consult a Doctor: For serious or persistent infections, consulting a podiatrist or dermatologist is essential to receive an accurate diagnosis and an effective treatment plan.

  • Potential Side Effects: Some users may experience skin irritation, redness, or allergic reactions from the ingredients in Vicks.

In This Article

The Key Antifungal Ingredients in Vicks

While Vicks VapoRub is not marketed as an antifungal medication, some of its components have demonstrated fungicidal properties in various studies. The combination of these volatile, naturally derived compounds is what is believed to give Vicks its potential, albeit unproven, effectiveness against fungal infections, particularly toenail fungus (onychomycosis). The key ingredients include:

  • Camphor: As a topical analgesic and cough suppressant, camphor is a volatile substance derived from the wood of the camphor tree. Lab tests have shown it can inhibit the growth of certain fungi that cause nail infections.
  • Eucalyptus Oil: This oil, sourced from the eucalyptus tree, is a natural antiseptic and has demonstrated broad-spectrum antifungal activity against various fungi and yeasts. It is a recognized active ingredient in the Vicks formulation.
  • Menthol: A compound derived from mint plants, menthol is a known anti-Candida agent. Studies have shown that it can inhibit fungal growth by affecting the integrity of the fungal cell membrane. It is also responsible for the signature cooling sensation of Vicks VapoRub.
  • Thymol (in some formulations): A compound found in thyme oil, thymol has also been identified as a potent antifungal agent. While it may not be listed as an active ingredient in all Vicks products, its presence in related essential oils and some historical formulations is noted.

The Science Behind Vicks and Fungus

The primary mechanism through which Vicks's ingredients are thought to combat fungus is by disrupting the cellular structure of fungal organisms. These compounds are known as monoterpenes, and they have been shown to affect the fungal cell membrane, which can lead to cell damage and death. The volatile nature of these oils also creates an unfavorable, suffocating environment for the fungus, which thrives in moist, closed-off conditions.

Furthermore, the petroleum jelly base of Vicks may play an indirect role. When applied and covered, this thick, occlusive ointment can seal off the affected nail, trapping the volatile antifungal vapors and starving the fungus of oxygen. This creates a hostile microenvironment that hinders the fungus's ability to grow and spread.

Vicks for Toenail Fungus: A Closer Look at the Evidence

Clinical evidence for using Vicks VapoRub specifically for toenail fungus, or onychomycosis, is limited but exists in one notable study. A small 2011 pilot study involved 18 participants who applied Vicks daily for 48 weeks.

  • Positive Effects: 15 out of the 18 participants (83%) showed a positive treatment effect, with some achieving a complete clinical and mycological cure.
  • Cure Rate: After nearly a year of treatment, 27.8% of the participants were completely cured, while 55.6% experienced partial clearance.
  • Limitations of the Study: This was a very small-scale study, and its findings are not representative of the broader population. Some experts also note that Vicks may not be effective against T. rubrum, the most common type of fungus causing onychomycosis.

Vicks vs. Prescription Antifungal Treatments

For those considering Vicks, it is important to understand how it compares to medically recognized treatments. Professional-grade treatments are typically more effective and specifically designed to combat onychomycosis.

Feature Vicks VapoRub (Home Remedy) Prescription Antifungals (e.g., Oral Terbinafine, Ciclopirox)
Approval Not FDA-approved for antifungal treatment. FDA-approved and clinically tested for specific fungal infections.
Effectiveness Limited scientific evidence, relies heavily on anecdotal reports. Effective for some minor infections, but unlikely to clear severe cases. Higher cure rates backed by extensive clinical trials. Topical versions may have limited nail penetration.
Penetration Poor penetration, especially through thick nails. Formulated for better penetration of the nail plate.
Treatment Time Can take up to a year or more, requiring consistent daily application. Variable, depending on the medication (e.g., oral treatments often shorter than topical).
Cost Relatively inexpensive. Significantly more expensive, often requiring health insurance.
Side Effects Mild skin irritation or allergic reactions are possible. Can include serious side effects (e.g., liver issues with oral meds) or local skin reactions.

Important Considerations and Limitations

  • Not a Guaranteed Cure: The effectiveness of Vicks is not guaranteed, and it may not work for everyone, especially those with severe or chronic infections.
  • Delayed Treatment: Relying solely on a home remedy like Vicks can delay more effective medical treatment, allowing the infection to worsen or spread.
  • Consult a Professional: Always consult a healthcare provider, such as a podiatrist or dermatologist, for a proper diagnosis and treatment plan. A doctor can determine the specific type of fungus and recommend the most effective course of action.
  • Safety: Applying Vicks may cause skin irritation or allergic reactions in some individuals. Discontinue use if you experience redness, burning, or itching.

Conclusion: Is Vicks a True Antifungal Cure?

While the active ingredients in Vicks VapoRub—camphor, eucalyptus oil, and menthol—possess mild antifungal properties, and anecdotal evidence and one small study suggest potential benefits, Vicks is not a reliable or proven cure for onychomycosis. Its effectiveness is highly variable, and it is not a substitute for medically approved antifungal treatments, which are backed by more robust scientific evidence and can target the infection more directly. For any persistent or severe fungal infection, consulting a medical professional is the safest and most effective approach to ensure a complete and lasting recovery.

For more detailed information on alternative treatments for onychomycosis, the National Institutes of Health (NIH) is a valuable resource that links to clinical studies and reviews of complementary therapies.

Frequently Asked Questions

There is no definitive evidence that Vicks VapoRub can cure nail fungus. A small 2011 study showed positive results for some participants, but Vicks is not a medically proven or FDA-approved treatment, and its effectiveness is limited, especially for stubborn infections.

The main ingredients with antifungal properties are camphor, eucalyptus oil, and menthol. Other compounds like thymol, found in related essential oils, may also contribute to the effect.

If it does work, it can take a very long time. The 2011 study reported that positive results were observed after 48 weeks of consistent daily application. For complete clearance, it can take even longer, as the nail needs to grow out fully.

No, prescription antifungal treatments are generally more effective and reliable than Vicks. Prescription medications are specifically formulated to penetrate the nail and fight the infection, unlike Vicks, which is primarily a cough suppressant.

Yes. Potential risks include skin irritation, redness, and allergic contact dermatitis, especially with prolonged use. Forcing the product under the nail can also cause trauma and worsen the condition.

Many podiatrists discourage using home remedies like Vicks because they are not reliably effective and can delay proper medical treatment. This can allow the infection to worsen and become more difficult to treat later.

While the ingredients may have broad-spectrum antifungal properties, Vicks is not recommended for other infections like athlete's foot or ringworm. Its use should be restricted to the purpose it was originally marketed for and always with a doctor's guidance.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.