Ketomac 10 DT contains ketorolac, a potent non-steroidal anti-inflammatory drug (NSAID) with strong pain-relieving and anti-inflammatory effects. The "DT" indicates it's a dispersible tablet designed to be dissolved in water for quicker absorption. It is primarily used for the short-term relief of moderate to severe acute pain and is not suitable for mild or chronic pain.
Therapeutic Uses and Indications
Ketomac 10 DT is typically reserved for acute, often post-procedural, pain where other pain relievers may not be sufficient. Its use in reducing pain, swelling, and inflammation makes it effective for various conditions, including:
- Post-operative pain management
- Musculoskeletal injuries
- Severe dental pain
- Severe menstrual pain (Dysmenorrhea)
- Other types of moderate to severe acute pain as determined by a healthcare provider
Mechanism of Action
Ketorolac inhibits the production of prostaglandins, chemical messengers that cause pain, inflammation, and fever, by blocking the enzyme cyclooxygenase (COX). This action provides rapid relief from pain and swelling for acute pain management.
Dosage and Administration
Ketomac 10 DT should be taken as prescribed. Oral ketorolac is typically limited to a maximum of five days due to the risk of serious side effects.
Guidelines for proper administration:
- Dissolve the tablet in water before taking.
- Take with food or milk to minimize stomach irritation.
- Do not crush or chew.
- Do not exceed the prescribed dose or duration.
- If a dose is missed, take it when remembered, or skip it if it's near the next dose time. Do not double doses.
Important Considerations and Side Effects
Patients should be aware of potential side effects and risks, which increase with long-term or high-dose use.
Common Side Effects:
- Nausea and vomiting
- Indigestion or heartburn
- Diarrhea or constipation
- Stomach pain
- Dizziness or drowsiness
- Headache
- Fluid retention (edema)
Serious Risks:
- Gastrointestinal (GI) bleeding and ulcers: Increased risk, potentially life-threatening.
- Cardiovascular thrombotic events: Increased risk of heart attack or stroke, especially in those with heart conditions. Contraindicated before or after CABG surgery.
- Renal complications: Can cause or worsen kidney problems.
- Bleeding disorders: Can increase bleeding risk.
- Hypersensitivity reactions: Including severe allergic reactions.
Comparison of Ketorolac (Ketomac 10 DT) to Other NSAIDs
| Feature | Ketorolac (Ketomac 10 DT) | Ibuprofen (e.g., Advil, Motrin) | Naproxen (e.g., Aleve, Naprosyn) |
|---|---|---|---|
| Potency | High potency, similar to opioids | Moderate potency | Moderate potency |
| Indication | Short-term management of moderate to severe acute pain | Mild to moderate pain, inflammation, and fever | Mild to moderate pain, inflammation, and fever |
| Duration of Use | Maximum of 5 days for oral use due to high risk | Suitable for short-term and sometimes long-term use (with caution) | Can be used longer-term (with caution), longer-acting than Ibuprofen |
| GI Risk | High risk of GI bleeding and ulcers, especially with longer use | Moderate risk of GI bleeding and ulcers | Moderate risk of GI bleeding and ulcers, often taken less frequently |
| Cardiovascular Risk | Elevated risk of heart attack or stroke | Elevated risk of heart attack or stroke | Elevated risk of heart attack or stroke |
Conclusion
Ketomac 10 DT (ketorolac) is a powerful NSAID for the short-term treatment of moderate to severe acute pain, such as post-operative pain or injuries. Its rapid action is useful when stronger analgesia is needed. Use is limited to about five days to reduce the risk of serious side effects like GI bleeding and cardiovascular issues. As a dispersible tablet, it offers a fast-acting option. It must be used under medical supervision, taken with food, and alcohol should be avoided. Following the prescribed dosage and duration is crucial for safety and effectiveness. For complete information, consult official medical resources like the U.S. National Library of Medicine.
