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What is meloxicam?: A Comprehensive Guide to this NSAID

1 min read

In 2023, meloxicam was the 27th most commonly prescribed medication in the United States, highlighting its widespread use for pain and inflammation. What is meloxicam? It is a prescription-only nonsteroidal anti-inflammatory drug (NSAID) primarily used to treat the symptoms of various forms of arthritis.

Quick Summary

Meloxicam is a prescription NSAID that treats pain, swelling, and stiffness from arthritis by inhibiting COX-2 enzymes. Available in various forms, it is taken once daily. Patients should be aware of serious heart and stomach risks.

Key Points

  • Prescription NSAID: Meloxicam is a prescription-only, nonsteroidal anti-inflammatory drug used for arthritis and inflammation.

  • Once-Daily Dosing: Its long half-life allows for once-daily administration.

  • Preferential COX-2 Inhibition: At lower doses, it preferentially inhibits the COX-2 enzyme.

  • Serious Boxed Warnings: Carries serious FDA boxed warnings for increased risk of heart attack, stroke, and life-threatening gastrointestinal bleeding or ulcers.

  • Risk of Interactions: Can have dangerous interactions with other medications and alcohol.

  • Medical Supervision Required: Due to serious risks, meloxicam should only be taken under the guidance of a healthcare professional.

In This Article

Understanding Meloxicam and How It Works

Meloxicam, an NSAID available under the brand name Mobic and in generic form, is prescribed to manage inflammation and pain. It is a prescription-only medication. Meloxicam works by inhibiting cyclooxygenase (COX) enzymes, which are involved in producing prostaglandins, substances that cause pain and inflammation.

Meloxicam preferentially inhibits the COX-2 enzyme at lower doses, which was intended to reduce gastrointestinal side effects compared to inhibiting COX-1. However, at higher doses, it loses this selectivity and can inhibit both enzymes. {Link: GoodRx https://www.goodrx.com/meloxicam/what-is} provides further information on meloxicam, including its forms, uses, risks, and interactions. A table comparing meloxicam and ibuprofen is also available on the {Link: GoodRx https://www.goodrx.com/meloxicam/what-is} website.

Conclusion

What is meloxicam? It is a prescription NSAID offering once-daily relief for inflammatory conditions like arthritis. While it may preferentially inhibit COX-2 at lower doses, it carries serious FDA boxed warnings for cardiovascular and gastrointestinal risks. It is crucial to use the lowest effective dose for the shortest duration under the guidance of a healthcare provider. Discuss all medications and health conditions with your doctor to determine if meloxicam is appropriate for your individual health profile.

Authoritative Link: MedlinePlus: Meloxicam

Frequently Asked Questions

Meloxicam is used to treat the symptoms of osteoarthritis, rheumatoid arthritis, juvenile idiopathic arthritis, and ankylosing spondylitis. It relieves pain, stiffness, and inflammation associated with these conditions.

Meloxicam is a longer-acting prescription NSAID compared to over-the-counter ibuprofen. Both treat pain and inflammation, but meloxicam's once-daily dosing provides more sustained relief.

Avoid taking meloxicam with other NSAIDs like ibuprofen or naproxen due to increased risk of serious side effects, such as stomach bleeding. Consult your doctor or pharmacist about taking it with acetaminophen.

Serious side effects include an increased risk of heart attack, stroke, and significant gastrointestinal issues like bleeding and ulcers.

It is not recommended to drink alcohol with meloxicam due to a significantly increased risk of stomach bleeding.

Meloxicam is typically taken once per day. Always follow your doctor's specific dosing instructions.

If you miss a dose, take it when you remember. If it's close to your next dose, skip the missed one. Do not take a double dose.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.