For travelers and residents accustomed to the UK market, navigating over-the-counter (OTC) medication in the USA can be confusing due to different brand names. Piriton, a popular antihistamine in the UK, is a prime example. The key to finding its US equivalent is to look for its active ingredient, which is where a slight naming convention difference is important.
The Active Ingredient: Chlorpheniramine
In the UK, Piriton's active ingredient is called chlorphenamine maleate. In the USA, the same compound is known as chlorpheniramine maleate. The small difference in spelling ('a' vs 'i') is due to different naming conventions, with 'chlorphenamine' being the International Nonproprietary Name (INN) and 'chlorpheniramine' being the United States Adopted Name (USAN). Both names refer to the same first-generation antihistamine drug.
What is chlorpheniramine?
Chlorpheniramine is a sedating or "drowsy" antihistamine that works by blocking the action of histamine, a substance the body releases during an allergic reaction. It is effective for treating a variety of allergic symptoms, including:
- Sneezing
- Runny nose
- Itchy or watery eyes
- Itchy nose or throat
- Hives and other itchy skin rashes
- Allergic reactions to insect bites and stings
US Brand Name: Chlor-Trimeton
The most recognizable US equivalent to Piriton is Chlor-Trimeton. Available over-the-counter, Chlor-Trimeton contains chlorpheniramine maleate and is used to relieve common allergy and cold symptoms. It's available in various strengths and formulations, including tablets and syrups, and is also sometimes found in multi-symptom cold and flu products.
Other common US brands
While Chlor-Trimeton is the most well-known, chlorpheniramine is also sold under numerous other generic and store-brand labels in the USA. Examples include:
- Aller-Chlor
- Allergy Relief (found in various store-brand versions)
- Generic Chlorpheniramine Maleate tablets
Piriton vs. US Equivalents: A Comparison Table
| Feature | Piriton (UK) | US Equivalents (e.g., Chlor-Trimeton) |
|---|---|---|
| Active Ingredient | Chlorphenamine maleate | Chlorpheniramine maleate |
| Primary Brand Name | Piriton | Chlor-Trimeton |
| Common Use | Hay fever, allergies, itchy rashes | Allergies, hay fever, cold symptoms |
| Availability | Over-the-counter (OTC) in pharmacies | Over-the-counter (OTC) in pharmacies and stores |
| Sedation Potential | Considered a sedating antihistamine, may cause drowsiness | Considered a sedating antihistamine, may cause drowsiness |
| Availability of Pediatric Forms | Liquid formulations are available | Liquid and chewable formulations are available |
Important Considerations for Chlorpheniramine
Because chlorpheniramine is a first-generation antihistamine, it can cause significant drowsiness, decreased coordination, and other side effects. Due to its sedative properties, it is not advisable to drive or operate heavy machinery until you understand how the medication affects you. It's also recommended to avoid alcohol consumption while taking chlorpheniramine, as it can worsen drowsiness and other side effects. For older adults, the risk of confusion, dizziness, and falls is heightened.
Alternatives and Combination Products
For those seeking non-drowsy alternatives, second-generation antihistamines like loratadine (e.g., Claritin) or cetirizine (e.g., Zyrtec) are widely available in the USA. Additionally, chlorpheniramine is often included in multi-symptom cold and flu medicines in the USA alongside other active ingredients like acetaminophen (Tylenol) and decongestants. Always check the product label carefully to avoid taking duplicate active ingredients.
For more detailed information on chlorpheniramine, you can visit the MedlinePlus drug information page.
Conclusion
In summary, if you are looking for Piriton in the USA, you should ask for a product containing chlorpheniramine maleate. The most common US brand name for this medication is Chlor-Trimeton, but it is also available under various other brand and generic labels. While it provides effective relief for allergic symptoms, its sedating effects are a key consideration when choosing this medication, and non-drowsy alternatives are readily available.
