What is Seeskin P used for?: Applications and Benefits of this Collagen Particle Dressing

October 6, 2025 •

4 min read

According to the National Institutes of Health, chronic wounds affect millions globally and represent a significant healthcare burden. Seeskin P is an innovative, nanotechnology-based sterile wound dressing, containing collagen particles and chitosan, developed to treat a wide range of these non-healing ulcers and wounds.

Quick Summary

Seeskin P is a collagen and chitosan-based particle dressing used to promote healing in various chronic wounds, such as diabetic foot ulcers, bedsores, venous ulcers, and traumatic wounds. The nanotech particles increase contact with the wound bed, stimulate granulation tissue, and help protect against infection.

Key Points

Designed for Chronic Wounds: Seeskin P is primarily used to treat chronic, non-healing ulcers, such as diabetic foot ulcers, pressure sores, and venous ulcers.
Stimulates Granulation: The bioengineered Type I collagen particles stimulate the formation of new tissue (granulation) in deep or irregular wounds.
Inhibits Infection: Chitosan, a key ingredient, provides a protective effect against bacterial infections, which can impede healing.
Nanoparticle Technology: The small particle size of Seeskin P ensures excellent wound bed coverage and bioavailability, even in deep or undermined cavities.
Easy and Bio-absorbable Application: It is applied as a powder and is fully bio-absorbable, meaning it doesn't need to be removed, reducing trauma to the wound bed.
Conforms to Irregular Surfaces: The particulate nature allows it to conform perfectly to irregularly shaped or tunneling wounds, maximizing contact.
Minimizes Scarring: By modulating the inflammatory process, the components of Seeskin P help to promote effective healing and reduce the risk of excessive scarring.

Understanding the Core Components: Collagen and Chitosan

Seeskin P is a sophisticated wound dressing that owes its efficacy to its two primary ingredients: bioengineered Type I collagen and chitosan. These natural biopolymers play distinct yet complementary roles in the wound healing process.

The Role of Collagen

Collagen is the most abundant structural protein in the body and is a crucial component of connective tissues, including the skin. In the context of wound care, collagen provides a natural scaffold that supports cellular migration, proliferation, and new tissue development. The Type I collagen used in Seeskin P, derived from peptides, is easily absorbed and helps to:

Encourage granulation tissue formation: Granulation is the new connective tissue and tiny blood vessels that form on the surfaces of a wound during the healing process. The collagen particles actively stimulate and promote faster granulation, particularly in deep wounds.
Support tissue remodeling: Collagen dressings help organize newly formed collagen fibers, strengthening the new tissue and promoting a healthier, more organized healing process.

The Role of Chitosan

Chitosan is a natural biopolymer that works alongside collagen to create an optimal healing environment. Its key function within the Seeskin P formulation is to protect the wound from infection. This is a critical feature, as infection can significantly delay or halt the healing of chronic wounds.

Specific Uses and Indications for Seeskin P

Seeskin P is designed for the management of various complex and chronic wounds that have stalled or are difficult to heal. The small, sterile particles allow for excellent coverage on irregular or deep wound sites, providing direct contact with the entire wound bed.

Types of Wounds Treated by Seeskin P

Diabetic Foot Ulcers: Often non-healing due to poor circulation and neuropathy, these ulcers benefit from Seeskin P's ability to promote healthy granulation in deep cavities.
Pressure Ulcers (Bedsores): Seeskin P is indicated for pressure ulcers, providing a barrier and support for tissue regeneration in immobilized patients.
Venous Ulcers: These ulcers, caused by poor blood circulation, can become chronic. The dressing helps manage the wound bed to support healing.
Traumatic Wounds: For traumatic wounds healing by secondary intention, Seeskin P encourages faster tissue formation to fill the defect.
Dehisced Surgical Wounds: Seeskin P can be used to treat surgical wounds that have reopened, supporting the re-epithelialization and closure process.
Partial and Full-Thickness Wounds: The dressing is suitable for a wide range of wound depths.
Donor Sites: It aids in the healing of skin graft donor sites, minimizing scarring and promoting new skin growth.
Irregular and Undermined Wounds: The particulate form makes it ideal for hard-to-reach areas and tunneling wounds, ensuring the active components make contact with all parts of the wound bed.

The Seeskin P Advantage: A Nanotechnology Approach

Unlike traditional sheet dressings, the particulate nature of Seeskin P, based on nanotechnology, offers several advantages for complex wounds:

Maximum Wound Bed Contact: The tiny nanoparticles conform precisely to irregular wound surfaces, including deep cavities and undermined areas, maximizing the effective surface area for healing.
Promotes Healing from Within: The high surface area and intimate contact ensure that the healing properties of the collagen are delivered directly to where they are most needed, stimulating tissue regeneration from the base of the wound.
Bio-absorbable: The particles are designed to be absorbed by the body over time, which reduces the need for painful and potentially damaging removal of the dressing from the wound bed.

Comparison of Seeskin P with Other Wound Dressings


Feature	Seeskin P (Collagen Particles)	Standard Hydrogel	Traditional Gauze Dressing
Mechanism	Promotes granulation via collagen scaffold; inhibits bacteria with chitosan.	Maintains moist wound environment to aid debridement and healing.	Absorbs exudate; provides mechanical barrier.
Wound Type	Chronic, deep, irregular, and non-healing wounds.	Dry wounds, wounds with slough or necrotic tissue.	Abrasions, minor cuts, temporary cover.
Application	Applied as a granular powder and covered with a secondary dressing.	Applied as a gel, sheet, or impregnated gauze.	Applied directly to the wound, often with adhesive tape.
Key Benefit	Encourages rapid granulation in complex wounds; conforms to irregular shapes.	Soothes pain; aids autolytic debridement.	Readily available, absorbent, cost-effective for minor wounds.
Frequency of Change	Can be left in place for several days, depending on wound drainage.	Changes vary; often needs more frequent changes for high exudate.	Requires frequent changes to prevent adherence and infection.
Absorption	Absorbs exudate and turns into a gel that stays in contact with the wound bed.	Varies, typically low to moderate.	Absorbs exudate but can dry out and adhere to the wound.
Bio-absorbability	Yes, particles are bio-absorbable, eliminating the need for removal from the wound bed.	Not applicable, as it is a topical gel or sheet.	No, must be removed and can cause trauma to new tissue.

Conclusion

In summary, Seeskin P is a sterile wound dressing composed of collagen particles and chitosan, designed specifically for the treatment of chronic, non-healing wounds. Its nanoparticle formulation ensures superior contact with the wound bed, promoting healthy granulation from within and protecting against infection. It is a valuable tool for managing difficult-to-heal ulcers, bedsores, and other complex wounds, providing an advanced alternative to more conventional dressings. As with any medical product, it is crucial to use it under the guidance of a healthcare professional and to follow all application instructions carefully. For further clinical details and usage guidelines, refer to authoritative sources such as those found on the National Institutes of Health website.

Frequently Asked Questions

Seeskin P is a sterile particle dressing primarily made from bioengineered Type I collagen and chitosan, which are natural biopolymers that assist in the wound healing process.

First, the wound bed should be thoroughly washed with normal saline. A generous coating of the Seeskin P particles is then applied to cover the entire wound bed, followed by a secondary absorbent dressing.

Seeskin P is indicated for a wide range of chronic wounds, including diabetic foot ulcers, pressure ulcers (bedsores), venous ulcers, traumatic wounds, partial and full-thickness wounds, and dehisced surgical wounds.

The dressing's frequency of change depends on the amount of wound drainage, but it can typically be left in place for up to three days.

Seeskin P should not be used on patients with a known allergy to collagen or who have active vasculitis. If signs of sensitization occur, it should be discontinued.

The nanotechnology-based nanoparticles provide a high surface area that makes intimate contact with the wound bed, promoting better bioavailability and more efficient granulation tissue formation, especially in deep wounds.

While it can be used for abrasions and surface wounds, its formulation and benefits are particularly suited for complex, chronic, or stalled wounds where other treatments have failed to promote effective healing.

Yes, the dressing is completely bio-absorbable. As the healing progresses, the body naturally absorbs the collagen particles, so they do not need to be removed from the wound bed.