Senna is a natural, over-the-counter medication derived from the leaves and fruit of the senna plant (Cassia acutifolia or Cassia angustifolia). In adults, it is primarily used as a stimulant laxative for the short-term treatment of occasional constipation. It can also be prescribed to empty the bowels before certain medical procedures and surgeries.
The Mechanism of Action of Senna
Senna is classified as a stimulant laxative. Its active compounds, sennosides, are converted in the colon by bacteria into rhein anthrones. These stimulate intestinal muscle contractions (peristalsis) and increase fluid and electrolyte influx into the colon, facilitating bowel movements.
Adult Dosage and Administration
Available in various oral forms like tablets and liquids, senna is typically taken once or twice daily. Taking it at bedtime can result in a bowel movement within 6 to 12 hours. It is for short-term use only, usually no more than a week, as prolonged use can lead to dependency. Staying hydrated is also important when using senna.
Safety Profile and Potential Side Effects
While generally safe for short-term use, potential side effects should be considered. Common side effects may include stomach cramping, diarrhea, and reddish-brown urine discoloration. Serious risks associated with long-term use include electrolyte imbalance (particularly potassium) and laxative dependence. Rectal bleeding requires immediate medical attention. For a more detailed list of side effects, consult {Link: Drugs.com https://www.drugs.com/npp/senna.html}.
Senna vs. Other Laxatives: A Comparison
Understanding how senna compares to other laxative types can be helpful. A comparison of senna (stimulant), psyllium (bulk-forming), lactulose (osmotic), and docusate (stool softener) based on mechanism, onset, use case, and considerations can be found on {Link: Drugs.com https://www.drugs.com/npp/senna.html}.
Important Precautions and Contraindications
Senna is not suitable for everyone and may interact with certain medications. Avoid senna if you have unexplained abdominal pain, intestinal obstruction, or inflammatory bowel disease. Use during pregnancy and breastfeeding is generally not advised without medical guidance. Elderly adults should use senna cautiously due to increased risks of dependency and electrolyte issues. Senna can interact with medications like digoxin and diuretics, potentially causing potassium depletion. Consult a healthcare professional for guidance.
Conclusion
To answer, what is senna used for in adults? Its primary use is for the short-term relief of occasional constipation and for bowel preparation. It acts as a stimulant laxative, typically working within 6–12 hours. Limit use to short durations to avoid dependence and side effects. Always follow directions and consult a doctor for persistent constipation or before starting senna. Often, lifestyle changes are the initial approach to constipation relief.
Further Reading
- MedlinePlus: Senna
- {Link: MedlinePlus https://medlineplus.gov/druginfo/meds/a601112.html}