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What is tall man lettering? An Essential Guide to a Critical Medication Safety Practice

4 min read

A 2008 survey by the Institute for Safe Medication Practices (ISMP) revealed that 87% of healthcare practitioners could recall at least one instance where tall man lettering personally prevented a medication error. This visual strategy, which emphasizes the unique parts of similar drug names with uppercase letters, is a key component of modern medication safety protocols designed to prevent potentially harmful mix-ups.

Quick Summary

Tall man lettering uses capitalized sections of drug names to highlight visual differences between similar-looking or -sounding medications, acting as a crucial safeguard against dispensing and administration errors.

Key Points

  • Definition: Tall man lettering is a visual medication safety technique that capitalizes specific letters in drug names that look or sound alike to prevent confusion.

  • Purpose: The primary purpose is to differentiate between look-alike/sound-alike (LASA) drug names, thereby reducing the risk of medication errors in prescribing, dispensing, and administration.

  • Examples: Common examples include predniSONE and prednisoLONE, or vinBLAStine and vinCRIStine, where the capitalized portion highlights the unique identifying part of the name.

  • Endorsement: Key organizations like the FDA and the Institute for Safe Medication Practices (ISMP) actively promote and maintain lists of drug names recommended for tall man lettering.

  • Context: TML is most effective when integrated into a comprehensive medication safety strategy that also includes other measures, such as barcode verification and electronic alerts.

  • Effectiveness: While studies confirm its ability to improve the visual differentiation of drug names, its real-world impact on error rates is most significant when used consistently across multiple healthcare systems.

In This Article

Understanding Tall Man Lettering

Tall man lettering (TML) is a safety measure in pharmacology that uses a mixture of uppercase and lowercase letters to differentiate drug names that look or sound alike, a category known as LASA (look-alike/sound-alike) drugs. By capitalizing the dissimilar parts of otherwise similar names, TML draws attention to the specific visual cue that distinguishes one medication from another. The technique is a low-cost, effective strategy that serves as an extra layer of protection against human error in the healthcare setting.

For example, the names prednisone and prednisolone are very similar and easy to confuse, but using tall man lettering makes them distinct: predniSONE and prednisoLONE. The capitalization is intentional, focusing the eye on the key difference to prevent a mix-up during prescription, dispensing, or administration. The ultimate goal is to minimize the potential for medication errors and enhance overall patient safety.

Where is Tall Man Lettering Used?

Tall man lettering is not confined to a single format but is integrated across multiple stages of the medication process. This widespread implementation ensures consistent visual cues for healthcare professionals at all points of care. Key areas of application include:

  • Pharmacy computer drug selection screens: Helping pharmacists and technicians select the correct drug from a digital list.
  • Computer-generated pharmacy labels: Printed labels on medication bottles and packaging that provide a clear visual distinction.
  • Automated dispensing cabinet (ADC) screens: On-screen displays in hospital ADCs show drug names with TML, assisting nurses during administration.
  • Medication administration records (MARs): These records, whether digital or physical, list drugs using TML to prevent nurses from administering the wrong medication.
  • Preprinted order forms: Some order sheets use TML to help prescribers avoid writing down the wrong medication.
  • Drug product labels: Pharmaceutical manufacturers voluntarily use TML on labels to distinguish their products from competitors with similar names.

History and Endorsement by Leading Safety Organizations

The practice of tall man lettering was developed and promoted by medication safety advocates in response to a growing number of errors linked to drug name confusion. The Institute for Safe Medication Practices (ISMP), a non-profit organization dedicated to preventing medication errors, was instrumental in coining the term and creating the initial lists of recommended names.

In 2001, the US Food and Drug Administration (FDA) launched its Name Differentiation Project to address the issue of look-alike drug names. The agency's initiative involved evaluating reports of name confusion and requesting manufacturers voluntarily revise labels to use TML. The FDA now maintains a list of established drug names where TML is recommended, and the ISMP continues to update and expand on this list. Other major bodies, including the Joint Commission, have also recommended its use.

The Efficacy Debate and Patient Safety

While widely adopted, the effectiveness of TML has been a subject of study and debate within the medical community. Some research has shown that TML significantly reduces errors in a laboratory setting, where participants were asked to identify and select drug names. For example, eye-tracking studies have found that TML leads to fewer errors in selection tasks. A survey of healthcare professionals conducted by ISMP also found overwhelming support, with a large majority feeling it helped prevent errors.

However, some real-world studies have shown mixed results. A 2016 study, for instance, found no significant change in error rates in children's hospitals following a 2007 recommendation to adopt TML. Critics noted, however, that the study had methodological limitations, such as not recording how or if TML was implemented. This highlights a crucial point: TML is most effective when used consistently and as part of a multi-faceted approach to medication safety. It is a tool to be used alongside other strategies, not as a standalone solution.

Comparison: Traditional vs. Tall Man Lettering

Feature Traditional Lettering Tall Man Lettering Impact on Safety
Appearance Uniform lowercase or uppercase lettering. Mixed-case, with specific letters capitalized. Traditional lettering offers no visual differentiation for similar names, increasing error risk.
Focus Relies on the user reading the entire word carefully. Visually highlights the dissimilar parts of the drug name. TML draws the eye to the key differences, helping to prevent confirmation bias and misreading.
Error Prevention Does not specifically address LASA drug name confusion. Directly targets and reduces confusion caused by LASA names. TML adds a visual safety check, helping slow down the process and prompting verification.
Implementation Standard for all printed and digital text. Requires specific, consistent formatting across all platforms (labels, software, etc.). Requires a coordinated effort across healthcare systems, but provides a tangible safety benefit.

Limitations and Complementary Strategies

Despite its benefits, TML is not a cure-all for medication errors. It has limitations, and its effectiveness is dependent on proper implementation and user training. Concerns include the potential for alert fatigue if overused and the lack of a universal standardization rule across all systems.

Therefore, TML must be used in conjunction with other medication safety strategies, including:

  • Barcode Scanning: Using barcodes to verify the medication, dose, and patient at the point of care.
  • Electronic Health Records (EHRs): Employing clinical decision support systems that alert clinicians to potential drug name conflicts.
  • Separate Storage: Physically separating drugs with similar names on pharmacy and patient care unit shelves.
  • Indications: Including the drug's indication (the reason for its use) on prescriptions and medication records.

Conclusion

What is tall man lettering? It is an established and recommended technique in pharmacology that utilizes mixed-case lettering to reduce medication errors associated with confusing drug names. Endorsed by major patient safety organizations like the FDA and ISMP, it serves as an important visual cue to draw attention to the key differences between similar drug names. While it is a proven strategy for reducing visual-based errors, it is most effective when used as part of a broader, multi-layered medication safety system. The implementation of TML, alongside technologies like barcode scanning and clinical decision support, remains a critical and proactive measure to protect patients from potentially devastating errors.

For more information on recommended drug names using TML, you can consult the official FDA Name Differentiation Project list.

Frequently Asked Questions

Tall man lettering is necessary because many medications have names that are visually and phonetically similar. This can lead to potentially harmful mix-ups, especially in busy, high-stress environments. TML serves as an immediate visual cue to differentiate these names and prevent errors.

The concept of tall man lettering was developed and promoted by medication safety advocates, most notably the Institute for Safe Medication Practices (ISMP). In 2001, the FDA officially launched a name differentiation project and began recommending TML for certain drug name pairs.

Examples of drug pairs that use tall man lettering include acetoHEXAMIDE and acetaZOLAMIDE, buPROPion and busPIRone, and predniSONE and prednisoLONE. Lists of these pairs are maintained by the FDA and ISMP.

Yes, tall man lettering is used for generic, brand-name, and brand-generic drug name pairs to minimize confusion. Both the FDA and ISMP lists include examples across these categories.

No, tall man lettering is a visual aid and a single strategy within a larger medication safety system. It does not eliminate all risk and must be used in conjunction with other safety protocols like barcode scanning, electronic alerts, and sound prescription practices.

Healthcare facilities can ensure consistent use by implementing policies based on the FDA and ISMP recommendations. This includes updating computer systems, automated dispensing cabinets, and medication labels to use the standardized TML formatting.

The FDA initiated its Name Differentiation Project in 2001 and maintains a list of established generic drug names for which TML is recommended. The agency requests that manufacturers voluntarily incorporate TML on their product labels.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.