Skip to content

What is the best medicine to stop a cold? A Symptom-Based Guide

4 min read

Over 200 viruses can cause the common cold, and no single medication can cure it. So, what is the best medicine to stop a cold? The most effective approach is to treat your specific symptoms with the right over-the-counter (OTC) products and support your body's natural recovery process.

Quick Summary

The common cold has no cure, but various over-the-counter medications can effectively manage symptoms. Learn which types of medicine target specific ailments like congestion, cough, fever, and aches, along with the importance of rest and hydration.

Key Points

  • No Cure Exists: There is no medication that can cure the common cold; treatment focuses on managing symptoms to make you more comfortable.

  • Target Specific Symptoms: The best approach is to identify and treat your primary symptoms individually (e.g., pain, congestion, cough) rather than using a multi-symptom product with unnecessary ingredients.

  • Rest and Hydration are Key: Adequate rest and plenty of fluids, such as water and clear broth, are crucial for supporting your body's immune response and speeding up recovery.

  • Differentiate Cough Type: Choose a cough suppressant (dextromethorphan) for a dry cough or an expectorant (guaifenesin) to help clear a wet, mucus-producing cough.

  • Avoid Antibiotics: The common cold is a viral infection, making antibiotics completely ineffective. Do not request them from your doctor.

  • Consult Before Treating Children: OTC cold medicines are not recommended for children under 4 years old. Focus on proven home remedies like saline nasal spray and honey for older kids.

  • Use Caution with Combination Products: Be vigilant when taking combination cold and flu products to avoid accidentally overdosing on active ingredients also found in single-ingredient medicines.

In This Article

No medication can cure the common cold, as it is a viral infection that must run its course. However, an array of over-the-counter (OTC) medicines and home remedies can provide significant relief from bothersome symptoms. The key to successful treatment is to identify your primary symptoms and choose a product designed to target them. Rest and staying hydrated are also crucial components of recovery.

How to Treat Cold Symptoms with OTC Medications

Targeting specific symptoms is the most effective way to use cold medicine. Instead of reaching for a single multi-symptom product, consider treating each ailment individually to avoid taking unnecessary medication.

Pain and Fever Reducers

For headaches, body aches, and fever, pain relievers are your best option.

  • Acetaminophen (Tylenol): An effective pain reliever and fever reducer that is gentle on the stomach.
  • NSAIDs (Ibuprofen, Naproxen): Nonsteroidal anti-inflammatory drugs like ibuprofen (Advil) and naproxen (Aleve) can reduce inflammation, fever, and body aches. However, those with kidney issues or stomach ulcers should avoid NSAIDs.

Nasal Decongestants

These medications help clear a stuffy nose by reducing swelling in the nasal passages.

  • Oral Decongestants: Pseudoephedrine (Sudafed) is a very effective oral decongestant but is kept behind the pharmacy counter due to regulations. Phenylephrine, another common oral decongestant, has been found by an FDA panel to be ineffective for congestion when taken by mouth, though it may work in nasal sprays.
  • Nasal Sprays: Topical decongestants like oxymetazoline (Afrin) can offer fast, temporary relief. Use for no more than three days to avoid rebound congestion.

Cough Medications

For coughs, the right medicine depends on whether your cough is productive (with mucus) or dry.

  • Expectorants (Guaifenesin): An ingredient like guaifenesin (Mucinex) thins and loosens mucus, making it easier to clear from your airways. This is for productive, or "wet," coughs.
  • Suppressants (Dextromethorphan): Medications containing dextromethorphan (Delsym, Robitussin DM) help suppress the cough reflex in the brain. These are best for dry, nonproductive coughs that interfere with sleep.

Antihistamines

Antihistamines are most effective for allergy symptoms, but older, first-generation versions can help with cold symptoms like sneezing and a runny nose due to their drying effect.

  • Diphenhydramine (Benadryl): This first-generation antihistamine causes drowsiness and can help with sleep while drying up a runny nose.
  • Second-generation antihistamines: Newer, non-drowsy antihistamines like cetirizine (Zyrtec) and loratadine (Claritin) are not effective for common cold symptoms.

Home Remedies and Self-Care

Sometimes, the best approach doesn't involve medication at all. These strategies can help your body recover and alleviate symptoms naturally.

  • Get plenty of rest. Sleep is when your body repairs itself, and sufficient rest is vital for a speedy recovery.
  • Drink plenty of fluids. Staying hydrated thins mucus and prevents dehydration. Water, juice, broth, and warm lemon water with honey are excellent choices. Avoid alcohol and caffeine.
  • Use saline nasal spray or a neti pot. Saltwater rinses can moisten nasal passages and help flush out mucus, providing relief from stuffiness. Always use sterile or distilled water for nasal irrigation.
  • Gargle with salt water. For a sore throat, gargling with warm salt water can temporarily reduce pain and swelling.
  • Use a humidifier. Adding moisture to the air can soothe irritated nasal passages and ease congestion and coughing, especially at night.
  • Try honey. A spoonful of honey can help soothe a cough in adults and children over one year old.

Comparison of Cold Medications by Symptom

Symptom Best Active Ingredient(s) Common Brand Examples Important Note
Aches/Fever Acetaminophen, Ibuprofen Tylenol, Advil Avoid aspirin in children due to Reye's syndrome risk.
Stuffy Nose Pseudoephedrine (Oral), Oxymetazoline (Nasal Spray) Sudafed (Oral), Afrin (Spray) Limit nasal sprays to 3 days to avoid rebound congestion.
Runny Nose/Sneezing Diphenhydramine (First-Gen Antihistamine) Benadryl, NyQuil Can cause drowsiness; not for daytime use.
Dry Cough Dextromethorphan (Suppressant) Delsym, Robitussin DM Suppresses the cough reflex.
Wet Cough (with Mucus) Guaifenesin (Expectorant) Mucinex Helps thin mucus to make coughs more productive.

What to Avoid When You Have a Cold

  • Antibiotics: Antibiotics are ineffective against the common cold because it is caused by a virus, not bacteria. Using antibiotics unnecessarily contributes to antibiotic resistance.
  • OTC Medications for Young Children: The CDC and FDA do not recommend OTC cough and cold medicines for children under 4 years old due to potential for serious side effects. For children, focus on natural remedies like rest, fluids, and saline drops.
  • Mixing Medications: Be careful when using combination products to ensure you don't double up on active ingredients by also taking single-ingredient medicines. Read all labels carefully.

Conclusion

While there is no cure for the common cold, a well-informed approach to managing symptoms can help you feel better and recover faster. Identifying and treating specific symptoms with targeted over-the-counter medications, alongside consistent self-care measures like rest and hydration, is the most effective strategy. Always read product labels, follow dosing instructions, and consult a healthcare provider if symptoms worsen or persist beyond 7 to 10 days. For many, simple home remedies combined with a targeted OTC product offer the best relief.

Mayo Clinic's Guide to Cold Remedies

Frequently Asked Questions

The common cold typically lasts for about 7 to 10 days, though lingering symptoms like a cough may persist for longer. If symptoms do not improve after 10 days, you should see a healthcare provider.

No. The FDA and CDC recommend against giving over-the-counter cough and cold medicines to children under 4 years old due to potential for serious side effects. For younger children, safe remedies include saline nasal drops and plenty of fluids.

No. Antibiotics only treat bacterial infections and are ineffective against the common cold, which is caused by a virus. Misuse of antibiotics can contribute to drug resistance.

Some studies suggest that zinc lozenges or syrup may slightly shorten the duration of a cold if taken within 24 hours of symptom onset. However, other studies have shown mixed results, and nasal zinc sprays carry the risk of permanent loss of smell.

For a sore throat, gargling with warm salt water can provide temporary relief. You can also suck on throat lozenges, ice chips, or hard candies (for adults and children over 6) to soothe the irritation.

You can, but it's important to read the label carefully. Many combination products contain several active ingredients. If you also take a single-ingredient medicine, you could accidentally take too much of a specific drug, such as acetaminophen.

Yes. While some OTC medications relieve symptoms common to both (e.g., pain relievers), only antiviral prescriptions like oseltamivir (Tamiflu) can treat the flu virus directly. Antibiotics are not effective for either illness.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.