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What Is the Best Topical Cream for Arthritis? A Comprehensive Guide

5 min read

According to Voltaren, it is the #1 doctor-recommended over-the-counter topical pain relief brand and is clinically proven to relieve arthritis pain, making it a strong contender for anyone wondering what is the best topical cream for arthritis. The ideal choice, however, depends on your specific symptoms, preferences, and overall health needs.

Quick Summary

This article explores the different types of topical creams for arthritis, including NSAID gels, counterirritants, and capsaicin. It compares their mechanisms of action, effectiveness, and considerations to help you select the most suitable option for your joint pain.

Key Points

  • Diclofenac (Voltaren): A topical NSAID that effectively reduces both pain and inflammation, providing prescription-strength relief for osteoarthritis in hands, wrists, elbows, knees, and feet.

  • Counterirritants (Menthol/Camphor): Provide immediate, temporary relief from minor aches by creating a heating or cooling sensation that distracts from the pain, but do not reduce inflammation.

  • Capsaicin Creams: Work over time by depleting pain-transmitting Substance P, but require consistent use for several weeks and can cause a temporary burning sensation.

  • Lidocaine Creams: Provide temporary, localized numbing by blocking nerve signals and are suitable for surface-level pain, not inflammation.

  • Informed Choice: Selecting the best cream involves assessing your specific pain type, location, tolerance, and consulting a healthcare provider, especially if you have other health conditions or take oral medications.

  • Safety Precautions: Always follow application instructions, wash hands thoroughly after use (especially with capsaicin), and avoid applying to broken or irritated skin.

In This Article

Understanding Topical Treatments for Arthritis Pain

Topical creams, gels, and patches offer a localized approach to managing arthritis pain. Instead of affecting your entire body like oral medications, they deliver active ingredients directly to the source of the pain. This can lead to faster relief for many and may result in fewer systemic side effects, though proper usage and potential interactions should always be considered. The most effective cream for you will depend on the type of pain you experience and the location of the affected joint.

Topical Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

Topical NSAIDs, such as diclofenac, are widely considered the most effective topical treatments for arthritis due to their anti-inflammatory properties. They work by inhibiting enzymes that lead to the production of inflammatory mediators, which reduces swelling, pain, and stiffness.

  • Active Ingredient: Diclofenac sodium (e.g., Voltaren Arthritis Pain Gel).
  • How It Works: It penetrates the skin to treat inflammation directly at the joint. For osteoarthritis of the knee, studies have shown significant improvement within a week of consistent use.
  • Considerations: While the risk of systemic side effects is lower than with oral NSAIDs, it is not zero. It is not recommended to use with other NSAID medication, and individuals with heart, kidney, or liver issues should consult a doctor. Use only on specific joints like hands, wrists, elbows, knees, ankles, and feet.

Counterirritants

Counterirritants create a heating or cooling sensation on the skin to distract the brain from the pain signals of the joint. They provide temporary, superficial relief and do not address the underlying inflammation.

  • Active Ingredients: Common ingredients include menthol, camphor, and methyl salicylate (oil of wintergreen).
  • How They Work: Products like Icy Hot and Biofreeze use menthol for a cooling effect, while Bengay uses a combination that provides a warming sensation. The sensory distraction can be very effective for immediate, short-term comfort.
  • Considerations: The effect wears off as the sensation fades. They can have strong odors and may cause minor skin irritation. Avoid using with heating pads or tight bandages.

Capsaicin Creams

Capsaicin, derived from chili peppers, works by depleting Substance P, a neurotransmitter that sends pain signals to the brain. This means that with repeated applications over time, it can reduce the perception of pain.

  • Active Ingredient: Capsaicin (e.g., Capzasin-HP).
  • How It Works: It causes an initial burning sensation that desensitizes nerve pain with regular use over several weeks.
  • Considerations: It must be used consistently for a few weeks to feel the full effects. The burning sensation can be intense for some, and users must be extremely careful to wash their hands thoroughly after application to avoid contact with eyes, mouth, and sensitive areas.

Lidocaine Creams

Lidocaine is a topical anesthetic that numbs the area by blocking nerve signals. It provides temporary relief from pain, but like counterirritants, it does not reduce inflammation.

  • Active Ingredient: Lidocaine (e.g., Aspercreme with Lidocaine).
  • How It Works: It blocks nerves from transmitting pain signals to the brain, offering targeted numbing relief.
  • Considerations: Relief is temporary and lasts for a few hours. It is most effective for minor joint pain and can be used on larger, flat areas like the back. The strength can vary between over-the-counter (OTC) and prescription versions.

Comparison of Popular Topical Arthritis Creams

Feature Topical NSAID (Diclofenac) Capsaicin Cream Counterirritant (Menthol/Camphor) Lidocaine Cream
Mechanism Inhibits inflammation at the joint level. Depletes Substance P, which transmits pain signals. Creates heating or cooling sensation to distract from pain. Blocks nerve signals to numb pain.
Onset of Relief Weeks of consistent use for full effect, some relief within 7 days. Weeks of consistent use required, initial burning sensation. Immediate, temporary relief. Within 30-60 minutes, temporary relief.
Inflammation Yes, actively reduces inflammation. No, only addresses pain signals. No, only provides sensory distraction. No, only provides numbing.
Side Effects Skin irritation, dry skin; low risk of systemic NSAID effects. Intense burning sensation, skin irritation. Skin irritation, strong odor. Skin irritation; generally considered safe.
Best For Moderate osteoarthritis pain in smaller, accessible joints. Patients who tolerate the burning and use consistently for long-term pain reduction. Immediate, temporary relief of minor aches. Localized, surface-level pain where numbing is desired.

How to Choose the Right Option

Selecting the right topical cream for arthritis involves considering several factors beyond just effectiveness. Your personal health profile, the type and location of your pain, and your preference for how a product feels and smells all play a role.

Consider the Nature of Your Pain

  • If your pain is caused by inflammation, such as with osteoarthritis, a topical NSAID like diclofenac may be the best choice as it addresses the root cause of the swelling and pain.
  • For immediate, short-term relief of minor aches, a counterirritant containing menthol or camphor can be effective at distracting from the pain.
  • If you're seeking a more long-term reduction of nerve-related pain signals and can tolerate an initial burning sensation, a capsaicin cream might be suitable.
  • For localized, surface-level pain where numbing is the priority, a lidocaine cream or patch can provide targeted, temporary relief.

Evaluate the Location of Your Pain

The affected joint's size and location can influence which product is easiest and most effective to apply. Gels and creams are often easier to apply to smaller joints like those in the hands and feet, while patches may be more suitable for a larger area.

Think About Your Sensitivity and Preferences

Some topical creams have strong medicinal odors that might be bothersome. Those with sensitive skin may react to certain active ingredients, so it is important to test a small area first. Consistency is key for some products, so consider if you can commit to applying it multiple times a day for an extended period.

Prioritize Safety and Medical Advice

Before starting any new medication, even an OTC topical, it is important to consult with your doctor or pharmacist. This is especially true if you have underlying health conditions, are pregnant or breastfeeding, or are taking other medications, particularly oral NSAIDs.

Conclusion

While many topical creams can provide relief, there is no single best option for everyone, and the best topical cream for arthritis is often a personalized choice. For targeted, anti-inflammatory relief, Voltaren (diclofenac gel) is a highly recommended and effective option. However, other products containing capsaicin, menthol, or lidocaine offer alternative mechanisms of action that may better suit certain types of pain or individual preferences. The decision should be based on the type of pain, joint location, personal tolerance, and safety considerations. Always consult a healthcare provider to ensure you are selecting the safest and most appropriate treatment for your needs. For more comprehensive information on arthritis and treatments, you can visit the Arthritis Foundation website.

Frequently Asked Questions

For moderate osteoarthritis pain and inflammation in accessible joints, Voltaren (diclofenac gel) is a highly recommended and clinically proven option. However, the best cream is personal, depending on your symptoms and preferences. Other effective ingredients include capsaicin, menthol, and lidocaine.

The time varies by product. Counterirritants like Icy Hot provide immediate, temporary relief. Topical NSAIDs like diclofenac (Voltaren) may require up to seven days of consistent use for significant pain reduction. Capsaicin creams typically need regular, consistent application over a period of weeks to be effective.

Generally, yes. Diclofenac is a topical NSAID that reduces both pain and inflammation, making it highly effective for arthritis. Lidocaine is a numbing agent that blocks pain signals but does not treat the underlying inflammation.

Common side effects are typically limited to the application site and can include skin irritation, redness, or dryness. Capsaicin can cause a burning sensation. Topical NSAIDs, while safer than oral versions, can still pose risks for individuals with heart, kidney, or liver issues. Always review the product's safety information and consult a doctor.

You should not use multiple NSAID creams at the same time and should avoid combining a topical NSAID with oral NSAIDs unless directed by a doctor. Using creams with different active ingredients (e.g., a counterirritant and a capsaicin cream) is possible, but caution should be exercised, and a healthcare provider should be consulted first.

Yes, some natural options include capsaicin (derived from chili peppers) and essential oils like peppermint and eucalyptus, which act as counterirritants. Turmeric and ginger have anti-inflammatory properties and can be consumed, but their effectiveness as topical treatments is less studied. Consult a doctor before trying natural remedies.

Apply only to intact skin, never to open wounds or irritated areas. Use disposable gloves or wash your hands thoroughly after applying, especially with capsaicin, to prevent irritation elsewhere. Avoid using with heating pads or tight bandages, which can increase absorption and risk.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.