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What is the drug menovazin used for? A Guide to Its Pharmacology

4 min read

The global topical pain relief market was valued at approximately $11.1 billion in 2024, with non-opioid solutions making up the majority of sales. This article answers, 'What is the drug menovazin used for?', delving into its role as a topical combination medication for localized pain and itching.

Quick Summary

Menovazin is a topical solution used for its local anesthetic and pain-relieving properties. It is primarily indicated for nerve pain, muscle pain, joint pain, and itchy skin conditions.

Key Points

  • Primary Use: Menovazin is a topical solution used for local pain relief (analgesic) and itch relief (antipruritic).

  • Active Ingredients: It contains a combination of menthol, procaine (novocaine), and benzocaine in a 70% ethanol base.

  • Mechanism of Action: Menthol provides a cooling sensation while procaine and benzocaine act as local anesthetics, blocking pain signals in nerve fibers.

  • Key Indications: It is officially indicated for neuralgia (nerve pain), myalgia (muscle pain), arthralgia (joint pain), and itchy skin conditions.

  • Application: Apply externally to intact, painful areas as directed; do not use on broken skin, the face, or mucous membranes.

  • Safety: Not recommended for children under 12 or those with hypersensitivity to its components. Long-term use may cause dizziness or low blood pressure.

  • Systemic Absorption: When applied externally as directed, the drug's components are generally not absorbed into the systemic bloodstream.

In This Article

Introduction to Menovazin

Menovazin is a combination drug intended for external use, recognized for its analgesic (pain-relieving) and antipruritic (anti-itching) properties. It is most commonly available as an alcohol-based solution, though spray forms also exist for convenient application over larger areas. The solution is a clear, colorless liquid with a distinct menthol aroma. While primarily produced and used in Eastern European countries like Ukraine and Russia, it is available online in other regions. Menovazin's effectiveness stems from its unique combination of active ingredients that work together to provide targeted relief without being systemically absorbed into the bloodstream, making it a relatively safe option when used as directed.

The Pharmacology Behind Menovazin: Active Ingredients

The therapeutic effects of Menovazin are due to its three primary active substances suspended in a 70% ethanol base.

  • Menthol: When applied to the skin, menthol irritates nerve endings and stimulates cold receptors, creating a cooling sensation. This action acts as a counter-irritant, distracting from the sensation of pain. It also causes dilation of superficial blood vessels and enhances the effects of the other anesthetic components.
  • Procaine Hydrochloride (Novocaine): Procaine is a local anesthetic with moderate activity. It functions by blocking sodium channels in nerve fibers. This blockage prevents the generation of pain impulses at the sensory nerve endings and stops their transmission to the brain.
  • Benzocaine (Anesthesin): Benzocaine is another local anesthetic, primarily used for surface anesthesia. Like procaine, it blocks sodium channels to interrupt the pain signaling pathway, effectively numbing the skin.

Together, these components create a multi-faceted approach to pain and itch relief. Menthol provides an immediate cooling and distracting sensation, while procaine and benzocaine work to block the pain signals at their source.

Primary Indications and Uses

According to official instructions and common usage, Menovazin is primarily prescribed for the following conditions:

  • Neuralgia: Pain arising from a damaged or irritated nerve, such as sciatica or intercostal neuralgia (pain between the ribs).
  • Myalgia: Muscle pain, whether from physical exertion, injury, or hypothermia.
  • Arthralgia: Joint pain, which is not necessarily accompanied by inflammation. It helps improve mobility and reduce discomfort.
  • Pruritic Dermatoses: Skin conditions characterized by itching. Menovazin helps to relieve the itch and provide a soothing sensation.

Beyond these primary uses, it is also popularly used off-label for tension headaches (applied to temples), the initial symptoms of a common cold (rubbed on the chest), bruises, and insect bites to reduce itching and swelling.

How to Use Menovazin Safely

Menovazin is intended for external use only. The solution should be applied to the painful or itchy area of the skin and gently rubbed in as directed by a healthcare professional or the product instructions. The duration of treatment depends on the condition and the therapeutic effect achieved. It is crucial to follow these safety measures:

  • Do not apply to damaged, broken, or inflamed skin.
  • Avoid contact with the face, eyes, and mucous membranes (mouth, nose).
  • Do not use if you have a known hypersensitivity to any of its components (menthol, procaine, benzocaine).
  • The drug is not recommended for children under 12 years of age.
  • Use during pregnancy or breastfeeding is only advised if the expected benefit to the mother outweighs the potential risk to the fetus or child, and should be done with caution after consulting a healthcare provider.

While generally safe, long-term use can potentially lead to side effects such as dizziness, general weakness, and a drop in blood pressure. If any allergic reactions like skin redness, rash, or increased itching occur, use should be stopped immediately.

Comparison Table: Menovazin vs. Other Topical Analgesics

Feature Menovazin Capsaicin Cream Diclofenac Gel Lidocaine Patch
Mechanism Counter-irritant & Local Anesthetic (blocks sodium channels) Depletes Substance P (neurotransmitter for pain) NSAID (inhibits prostaglandin synthesis) Local Anesthetic (blocks sodium channels)
Sensation Cooling and numbing Warming or burning Generally neutral Numbing
Primary Use Nerve pain, muscle aches, itching Neuropathic pain, arthritis Arthritis, inflammation, sprains Post-herpetic neuralgia, localized pain
Active Ingredients Menthol, Procaine, Benzocaine Capsaicin Diclofenac Lidocaine
Prescription Needed Generally Over-the-Counter Over-the-Counter & Prescription Over-the-Counter & Prescription Over-the-Counter & Prescription

Conclusion

Menovazin is a versatile and effective topical medication used for relieving various types of localized pain and itching, including neuralgia, myalgia, and arthralgia. Its combination of a cooling counter-irritant (menthol) and two local anesthetics (procaine and benzocaine) allows it to provide rapid relief by creating a cooling sensation and blocking pain signals from reaching the brain. While it is widely used and considered safe for external application on intact skin, it is important to be aware of its contraindications, particularly avoiding use on damaged skin, the face, or in individuals with allergies to its components. As with any medication, consulting a healthcare professional for proper diagnosis and treatment guidance is always recommended.


For more information on the efficacy of topical anesthetics, you can review this study from the National Center for Biotechnology Information: Comparing the Efficacy of a Compound Topical Anesthetic Versus Benzocaine: A Pilot Study.

Frequently Asked Questions

Menovazin is primarily used as a topical local anesthetic for conditions like neuralgia (nerve pain), myalgia (muscle pain), arthralgia (joint pain), and to relieve itching from skin conditions.

The active ingredients are menthol, procaine hydrochloride (also known as novocaine), and benzocaine, typically in a 70% ethanol solution.

Menthol creates a cooling sensation that distracts from pain, while procaine and benzocaine block sodium channels in nerve endings, which stops pain signals from being sent to the brain.

No, it is strictly advised not to apply Menovazin to the face, mucous membranes, or on broken or damaged skin, as it can cause significant irritation.

Menovazin is not recommended for use in children under 12 years of age, according to official instructions.

Possible side effects include allergic reactions like skin redness, itching, and rashes. With prolonged use, some may experience dizziness, weakness, and lowered blood pressure.

It is sometimes used off-label for tension headaches by rubbing a very small amount into the temples. However, extreme care must be taken to avoid contact with the eyes.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.