What is the equivalent of Citrucel?: A Guide to Alternatives and Substitutes

October 9, 2025 •

5 min read

Over 70 million Americans suffer from chronic digestive diseases, including constipation. Citrucel, a popular bulk-forming laxative, is often used to manage this, but many seek alternatives. For those asking, 'What is the equivalent of Citrucel?', the answer ranges from direct generic products to other types of fiber supplements and laxatives.

Quick Summary

Citrucel's direct equivalent contains the same active ingredient, methylcellulose, such as Major Fiber Therapy. Other alternatives like Metamucil (psyllium husk) and Benefiber (wheat dextrin) work differently and may cause more gas. Lifestyle and osmotic laxative options also exist for constipation relief.

Key Points

Generic Equivalent: The most direct and affordable generic equivalent to Citrucel is Major Fiber Therapy, as both use the same active ingredient, methylcellulose.
Less Gas and Bloating: Citrucel and its generic are preferred by many with sensitive stomachs because the methylcellulose fiber is non-fermentable and less likely to cause gas compared to psyllium.
Psyllium Alternatives: Fiber supplements containing psyllium husk, like Metamucil, are effective bulk-formers but are fermentable and may cause more gas. Psyllium also offers heart health benefits by lowering cholesterol.
Other Fiber Options: Alternatives like Benefiber (wheat dextrin) dissolve easily and cause less gas, while FiberCon (calcium polycarbophil) is another low-gas fiber available in caplets.
Non-Fiber Alternatives: Osmotic laxatives (MiraLAX) and stool softeners (Colace) work through different mechanisms to relieve constipation and are suitable for those who don't respond well to fiber.
Crucial Lifestyle Changes: For managing constipation, increasing dietary fiber from whole foods, drinking plenty of water, and regular exercise are foundational and often recommended before or in addition to supplements.
Individual Needs: The best alternative depends on personal tolerance for gas, desired format (powder vs. caplet), and whether additional benefits like heart health support are a priority.

Citrucel, with its active ingredient methylcellulose, is a well-known bulk-forming fiber supplement designed to treat occasional constipation and promote regularity. Its appeal lies in using a non-fermentable fiber, which means it is less likely to cause the excess gas and bloating associated with some other fiber types. When availability issues arise, or a more budget-friendly option is desired, it's helpful to understand the landscape of equivalents and alternatives.

The Direct Generic Equivalent

For those who prefer to stick with the exact same active ingredient for consistent, predictable results, the best equivalent is a generic version of methylcellulose.

Major Fiber Therapy: Manufactured by Major Pharmaceuticals, this product is the only true generic equivalent to Citrucel. It provides the same gentle, non-fermentable fiber and is often more affordable than the brand name. It's available in powder form, but note that the standard version contains sugar.

Other Bulk-Forming Fiber Alternatives

While not direct chemical equivalents, other bulk-forming laxatives operate on the same principle of adding bulk and water to the stool. However, they use different types of fiber, which can affect side effects and other benefits.

Metamucil (Psyllium Husk): This is one of the most common fiber supplements and is derived from the Plantago ovata plant. Unlike methylcellulose, psyllium is a fermentable, soluble fiber. It dissolves in the gut to form a gel-like coating, helping to soften stool. The fermentable nature of psyllium means it can cause more gas and bloating for some users. A key benefit of psyllium is its potential to help lower cholesterol and support heart health.
Benefiber (Wheat Dextrin): This is another popular soluble fiber supplement that dissolves completely in liquids, making it easy to add to beverages. It is less likely to cause gas than psyllium but also has a less pronounced bulking effect than Citrucel's insoluble fiber.
FiberCon (Calcium Polycarbophil): Available in caplet form, this fiber is also non-fermentable, similar to methylcellulose, so it is less likely to cause gas and bloating. It absorbs water in the intestinal tract to produce a soft, bulky stool.

Beyond Bulk: Other Types of Laxatives

If fiber supplements aren't the right fit, other laxative classes offer relief through different mechanisms. These are not direct equivalents but serve the same purpose of relieving constipation.

Osmotic Laxatives (e.g., MiraLAX): The active ingredient in MiraLAX is polyethylene glycol 3350. It works by drawing water into the colon to soften the stool, making it easier to pass. It is non-fermentable and generally well-tolerated, with a different mechanism of action than fiber.
Stool Softeners (e.g., Colace): Docusate sodium works by allowing water and fats to penetrate the stool, making it softer and easier to pass. It's suitable for people who need to avoid straining during bowel movements.
Stimulant Laxatives (e.g., Senna, Dulcolax): These products work by stimulating the intestinal muscles to increase bowel movements. They are typically for short-term use and should not be taken for more than a week without a doctor's advice.

Comparison of Citrucel and Alternatives

To help decide which product might be the best equivalent or alternative, consider the following comparison of the most common options.


Feature	Citrucel (Methylcellulose)	Major Fiber Therapy (Methylcellulose)	Metamucil (Psyllium Husk)	Benefiber (Wheat Dextrin)	FiberCon (Calcium Polycarbophil)
Active Ingredient	Methylcellulose	Methylcellulose	Psyllium Husk	Wheat Dextrin	Calcium Polycarbophil
Fiber Type	Non-fermentable, soluble/insoluble mix	Non-fermentable, soluble/insoluble mix	Fermentable, mostly soluble	Fermentable, soluble	Non-fermentable, insoluble
Common Side Effects (Gas)	Minimal gas and bloating	Minimal gas and bloating	More likely to cause gas and bloating	Less likely to cause gas	Less likely to cause gas and bloating
Mechanism	Adds bulk to stool by absorbing water.	Adds bulk to stool by absorbing water.	Forms gel, absorbs water, and softens stool.	Dissolves and provides soluble fiber.	Absorbs water to create bulk.
Other Benefits	Considered gentle for sensitive stomachs.	Cost-effective alternative.	May help lower cholesterol and blood sugar.	Easily dissolves, less bulking feel.	Available in convenient caplets.
Available Forms	Powder, Sugar-Free Powder, Caplets.	Powder (with sugar).	Powder, Sugar-Free Powder, Capsules, Wafers, Gummies.	Powder, On-the-go Sticks, Chewable Tablets, Gummies.	Caplets.

Natural and Lifestyle Alternatives

Before relying on supplements, several natural and lifestyle changes can significantly improve digestive regularity.

Increase Dietary Fiber: Focus on fiber-rich foods like fruits, vegetables, whole grains, nuts, seeds, and legumes. Both soluble and insoluble fibers from food sources are beneficial. Whole foods also provide a wider array of nutrients than supplements.
Stay Hydrated: Drinking plenty of fluids, especially water, is crucial when increasing fiber intake. Fiber absorbs water to create bulk, and without enough liquid, it can worsen constipation.
Exercise Regularly: Physical activity helps stimulate intestinal muscles and supports overall digestive function.

Conclusion: Choosing the Right Option

While Major Fiber Therapy is the only true equivalent of Citrucel, a variety of effective alternatives exist depending on individual needs and sensitivities. For those seeking the same low-gas experience as Citrucel, the generic methylcellulose or calcium polycarbophil (FiberCon) are excellent choices. If gas is not a primary concern and additional benefits like heart health are desired, psyllium-based products like Metamucil are a strong contender. For an easily dissolved supplement, Benefiber works well, and for different mechanisms of action, osmotic laxatives like MiraLAX or stool softeners like Colace are available. Ultimately, discussing options with a healthcare provider is the best way to determine the most suitable solution for long-term digestive health. You can find more information about fiber and digestive health on reliable sources like the Mayo Clinic website: https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/fiber/art-20043983.

How to Choose the Right Citrucel Alternative

Navigating the world of fiber supplements can feel overwhelming. Here's a quick guide to help you decide:

For Minimal Gas: Your best bet is a product with non-fermentable fiber. This includes Citrucel, its generic Major Fiber Therapy, and FiberCon.
For Heart Health Support: Psyllium-based products like Metamucil have soluble fiber that has been shown to help lower cholesterol as part of a healthy diet.
For Easy Mixing: Benefiber (wheat dextrin) dissolves completely in liquid, so it won’t thicken or add a gritty texture to your drink.
If You Dislike Powders: FiberCon and Citrucel are both available in caplet form, offering a convenient, easy-to-swallow alternative.
For a Different Mechanism: If fiber isn't helping or causes discomfort, consider osmotic laxatives like MiraLAX or stool softeners like Colace, which work differently.

Note: Always ensure adequate hydration when taking fiber supplements, regardless of the type, as insufficient fluid intake can worsen constipation. If constipation persists or worsens, seek medical advice.

Frequently Asked Questions

The main difference lies in their active ingredients and fiber types. Citrucel contains non-fermentable methylcellulose, which causes less gas, while Metamucil contains fermentable psyllium husk, which can cause more gas but also offers heart health benefits.

Yes, Major Fiber Therapy is the primary generic equivalent of Citrucel. It contains the same active ingredient, methylcellulose, and provides similar results for occasional constipation relief.

Citrucel is less likely to cause gas and bloating compared to psyllium-based fibers like Metamucil because its methylcellulose fiber is non-fermentable and is not broken down by gut bacteria.

Bulk-forming laxatives like Citrucel and Metamucil typically take between 12 and 72 hours to produce a bowel movement. For more immediate relief, other types of laxatives might be considered.

While fiber supplements are generally considered safe for daily use, it is always best to consult a healthcare provider for prolonged or regular use to ensure it's the right choice for your specific health needs.

Good non-fiber alternatives include osmotic laxatives like MiraLAX (polyethylene glycol), which draws water into the colon, or stool softeners like Colace (docusate sodium), which softens the stool itself.

Yes, several natural methods can help manage constipation. These include increasing dietary fiber from foods like fruits, vegetables, and whole grains, ensuring adequate fluid intake, and engaging in regular exercise.

Benefiber (wheat dextrin) is an alternative but not a direct equivalent. It is a soluble, fermentable fiber that dissolves easily without grit, but it may have a less pronounced bulking effect and can cause some gas.

If constipation persists or worsens after using a fiber supplement for a week, or if you experience severe symptoms, you should contact a healthcare provider. There may be a more serious underlying cause.

No, the Major Fiber Therapy powder equivalent to Citrucel contains sugar. If you require a sugar-free option, you should choose a different product.