Understanding the generic for Solaraze gel
The generic equivalent for Solaraze gel is diclofenac sodium 3% gel. Solaraze was a brand-name topical nonsteroidal anti-inflammatory drug (NSAID) specifically formulated to treat actinic keratosis (AK), a precancerous skin condition resulting from chronic sun exposure. While the brand-name product was discontinued, the generic formulation remains available by prescription. The effectiveness and uses of the generic product are identical to the original brand.
The active ingredient: Diclofenac sodium
Diclofenac sodium is the active ingredient in the gel. It belongs to the class of NSAIDs, which work by blocking certain enzymes (specifically COX-2) in the body responsible for inflammation and the growth of abnormal cells. While the exact mechanism for treating AK is not fully understood, the application of diclofenac sodium 3% gel to the affected skin helps stop the growth of the precancerous cells. It is important to note that this is different from other diclofenac topical products, such as the 1% gel (Voltaren), which are used for pain and arthritis rather than AK.
How to properly use diclofenac sodium 3% gel
Proper application is crucial for the effectiveness and safety of diclofenac sodium 3% gel. The typical regimen involves applying the gel twice daily for a period of 60 to 90 days, or as directed by a healthcare provider.
- Wash your hands before and after applying the gel.
- Apply a small amount of gel (about half a fingertip unit) to the affected areas of skin and gently smooth it over the lesions.
- Avoid applying the gel to open wounds, infected skin, or burns.
- Be careful to keep the gel away from your eyes, mouth, and nose. If accidental contact occurs, rinse thoroughly with water.
- Do not use occlusive dressings or bandages over the treated area unless specifically instructed by your doctor.
- You may not see the full effect of the treatment until up to 30 days after the full 60-90 day course has been completed.
Common and serious side effects
As with any medication, diclofenac sodium 3% gel can cause side effects. Local skin reactions are the most common, while more serious systemic effects are possible but rare due to low systemic absorption.
Common side effects include:
- Application site reactions such as rash, itching, dry skin, scaling, or peeling.
- Sun sensitivity, so it is important to limit sun exposure and wear protective clothing while undergoing treatment.
- Headache, stomach pain, nausea, or diarrhea.
Serious side effects, though rare, can include:
- Cardiovascular issues: NSAIDs, including topical diclofenac, can increase the risk of heart attack and stroke, especially with long-term use.
- Gastrointestinal bleeding: This risk is higher if used with other NSAIDs or for extended periods.
- Kidney or liver problems: Patients with pre-existing conditions should use this medication with caution.
- Severe allergic reactions: Symptoms may include hives, rash, swelling of the face, throat, or difficulty breathing.
Comparing diclofenac topical products and AK treatments
| Feature | Diclofenac Sodium 3% Gel (Generic for Solaraze) | Diclofenac Sodium 1% Gel (Generic for Voltaren) | Other AK Treatments (e.g., Fluorouracil) |
|---|---|---|---|
| Indication | Actinic Keratosis (AK) | Osteoarthritis pain | Actinic Keratosis, some skin cancers |
| Availability | Prescription only | Prescription and over-the-counter (OTC) | Prescription only |
| Concentration | 3% | 1% | Varies by formulation (e.g., 5%, 1%, 0.5%) |
| Duration of Treatment | Typically 60-90 days | Up to 3 weeks for OTC use; longer for prescription | Varies widely, can be several weeks |
| Side Effect Profile | Relatively well-tolerated with local skin reactions; rare systemic risk | Mild side effects; higher systemic risk with long-term/high-dose use | Can cause severe local irritation, redness, and peeling |
Cost and alternatives
The cost of diclofenac sodium 3% gel can vary depending on your insurance coverage and the pharmacy. Since the brand name is discontinued, the generic version is typically a more affordable option. Many insurance plans, including most Medicare plans, cover generic diclofenac sodium. Comparing prices at different pharmacies or using discount cards can help reduce out-of-pocket costs.
Your dermatologist may also discuss other treatment options for AK based on your specific needs, the location and number of lesions, and your tolerance for potential side effects. Other treatments may include cryosurgery, topical fluorouracil (Efudex, Carac), or imiquimod (Aldara, Zyclara).
Conclusion
In summary, the generic for Solaraze gel is diclofenac sodium 3% gel. This topical NSAID is a prescription-only medication used to treat actinic keratosis and is identical to the discontinued brand-name product. Patients should use it as directed for 60 to 90 days, be aware of common and rare side effects, and discuss all options with their healthcare provider. The generic form provides an effective and often more affordable alternative for treating this precancerous condition.
For more clinical information, the National Institutes of Health (NIH) provides reports on the long-term effectiveness of diclofenac sodium 3% gel treatment for actinic keratosis.
