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What is the Martindale used for? Understanding the Complete Drug Reference

4 min read

First published in 1883, Martindale: The Complete Drug Reference is a time-tested, essential tool used by healthcare professionals worldwide. This comprehensive pharmaceutical reference provides unbiased, evidence-based, and clinically evaluated information, detailing the characteristics and uses of drugs from across the globe.

Quick Summary

Martindale: The Complete Drug Reference is an authoritative international resource for healthcare professionals, offering encyclopaedic information on drugs, medicines, and proprietary preparations worldwide. It is used for drug identification, verifying clinical uses, assessing adverse effects, and comparing global drug information. The reference includes data on prescription, over-the-counter, herbal, and veterinary medicines.

Key Points

  • Global Drug Information: Martindale provides evaluated, unbiased information on thousands of drugs and medicines used throughout the world, with coverage of over 40 countries and regions.

  • Drug Identification: It is invaluable for identifying and understanding foreign medications, as it includes details on numerous proprietary preparations from around the globe.

  • Comprehensive Monographs: Detailed drug entries cover pharmacology, pharmacokinetics, indications, adverse effects, contraindications, and interactions, making it a robust reference tool.

  • Broad Substance Coverage: The reference extends beyond prescription drugs to include herbals, complementary medicines, investigational drugs, veterinary drugs, and toxic substances.

  • Evidence-Based and Respected: Martindale is highly respected for its objectivity, basing its content on published literature and providing extensive references for further research.

  • Digital Access: The resource is now primarily available digitally through MedicinesComplete, offering enhanced search functionality and regular updates for current drug data.

  • Clinical and Academic Standard: It is used widely by pharmacists, physicians, students, and researchers in both clinical and academic settings for both quick look-ups and in-depth study.

In This Article

What is Martindale: The Complete Drug Reference?

Martindale: The Complete Drug Reference is a foundational publication in the world of pharmacy and medicine, published by Pharmaceutical Press, the knowledge arm of the Royal Pharmaceutical Society. First published in 1883 under the name The Extra Pharmacopoeia, it has evolved over more than a century to become an indispensable resource. While its name has changed, its core purpose remains the same: to provide healthcare professionals with unbiased, comprehensive, and evaluated information on drugs and medicines used globally.

Unlike drug references with a limited national scope, Martindale stands out for its international coverage, making it a critical tool for professionals working across borders or treating patients who have received treatment abroad. The reference is now available in both digital and print formats, with the digital version providing up-to-date information via the MedicinesComplete platform.

The Primary Uses of Martindale

Martindale serves a wide range of practical purposes for healthcare professionals, including pharmacists, physicians, medical students, and researchers. Its comprehensive nature makes it suitable for both quick verification and in-depth study.

Identifying and Understanding Foreign Drugs

One of the most valuable uses of Martindale is its ability to help identify and understand medicines from other countries. With thousands of proprietary products listed from dozens of countries, it enables a practitioner to confirm the active ingredients, dosage forms, and equivalent alternatives for a patient arriving from overseas. This is crucial for ensuring continuity of care and avoiding potential drug-related issues.

Comprehensive Drug Information

For each drug, Martindale provides a detailed monograph that includes a wealth of data essential for safe and effective practice. This encyclopaedic information covers:

  • Chemical names, synonyms, and identifiers (e.g., CAS numbers, ATC codes)
  • Pharmacokinetics, including absorption, distribution, and metabolism
  • Pharmacodynamics and mechanism of action
  • Therapeutic indications, including approved and off-label uses
  • Adverse effects, contraindications, and precautions
  • Drug-drug, drug-food, and other interactions
  • Dosage and administration guidance for various populations

Accessing Disease Treatment Reviews

Beyond specific drug information, Martindale also provides extensive reviews on the treatment of various diseases. These reviews offer an overview of the condition and the drugs used in its treatment, supported by key literature references. This feature is invaluable for medical and pharmacy students and for clinicians needing a detailed refresher on a particular therapeutic area.

Information on Other Substances

Martindale's scope extends far beyond conventional prescription drugs. It is a source of reliable information on a broad spectrum of substances, including:

  • Herbal and complementary medicines
  • Investigational and veterinary drugs
  • Radiopharmaceuticals and contrast media
  • Vaccines and nutritional agents
  • Toxic substances, disinfectants, and pesticides
  • Drugs of abuse and recreational drugs, often with their 'street names'

A Standard for Academic and Clinical Settings

Martindale is a standard reference in health sciences libraries, hospitals, and pharmacies globally. Academics use it as a starting point for further research, while clinicians rely on its regularly updated, evidence-based content to inform daily decision-making.

Martindale vs. Other Drug References: A Comparison

While other valuable drug references exist, such as the British National Formulary (BNF), their focus and scope differ significantly. The comparison below highlights why Martindale is uniquely suited for international and comprehensive information needs.

Feature Martindale: The Complete Drug Reference British National Formulary (BNF)
Scope International, covering drugs worldwide Primarily focused on the United Kingdom
Information Depth Encyclopaedic, with detailed monographs, chemical structures, and extensive references Concise, practical, and user-friendly for immediate UK prescribing
Evidence Interpretation Reflects published literature and highlights varying opinions Offers its own recommendations based on licensed prescribing information and expert opinion in the UK
Coverage Includes herbals, toxins, investigational drugs, and proprietary preparations from many countries Limited to medicines used in the UK, with some exceptions
Ideal Use Case In-depth research, verifying foreign drugs, comparative studies Quick look-up of prescribing guidelines in the UK

Using Martindale in the Digital Age

With the final print edition released, Martindale's future is primarily digital, accessed via the MedicinesComplete platform. This evolution has brought several advantages, including faster updates, enhanced search capabilities, and the ability to link to other resources seamlessly. Users can search by drug name, chemical structure, therapeutic class, or manufacturer, making information retrieval highly efficient. Regular quarterly updates ensure that healthcare professionals have access to the most current drug data.

Conclusion: The Enduring Value of Martindale

Martindale: The Complete Drug Reference remains a gold standard in pharmaceutical literature for its unparalleled comprehensiveness and global scope. It is a tried-and-true resource that provides healthcare professionals with the practical, evidence-based, and unbiased guidance necessary for making informed clinical decisions. While other resources serve specific, regional, or specialized needs, Martindale continues to fill the crucial role of an exhaustive, internationally-focused drug information encyclopedia. Its transition to a digital-first format ensures its relevance and utility will continue to serve the global healthcare community for years to come. For anyone needing to research or validate decisions concerning drugs, herbals, and other pharmaceutical substances from around the world, Martindale remains the definitive answer to the question, what is the Martindale used for? It is used as a cornerstone of reliable pharmaceutical knowledge.

For more information on Martindale and to access the digital version, visit the MedicinesComplete website.

Frequently Asked Questions

Martindale is used by a broad range of healthcare professionals, including pharmacists, physicians, nurses, and medical students. It is also an important resource for researchers, academics, and regulatory professionals.

Martindale provides a global perspective, covering drugs and preparations from many countries, while the BNF is focused primarily on prescribing guidelines and recommendations within the UK. Martindale offers deeper, encyclopaedic information, while BNF is more concise for everyday UK prescribing.

Yes, Martindale is widely used for this purpose. It includes details on thousands of proprietary preparations from numerous countries and provides information on foreign names, ingredients, and alternatives.

Yes, Martindale includes extensive information on herbal medicines, traditional remedies, and complementary therapies, in addition to its coverage of conventional drugs.

Drug monographs in Martindale are very detailed, including chemical data, pharmacological properties, pharmacokinetics, approved indications, adverse effects, contraindications, drug interactions, dosage, and administration.

The 41st edition was announced as the final print version. Updates and future access are available exclusively through its digital platform, MedicinesComplete.

The digital version of Martindale, available via MedicinesComplete, is updated quarterly to ensure the information remains current and accurate.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.