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What is the pill that stops coughing?: An Overview of Antitussives and Expectorants

4 min read

Coughs account for nearly 30 million clinical visits a year, making them one of the most common reasons people seek medical care. This high demand for relief often leads to the question, 'What is the pill that stops coughing?', but the answer depends on the type of cough and the underlying cause.

Quick Summary

Different medications are used to treat dry versus productive coughs. Antitussives, like dextromethorphan, suppress the cough reflex, while expectorants, like guaifenesin, thin mucus. Prescription-strength options, such as benzonatate, are also available for more severe cases.

Key Points

  • Antitussives suppress the cough reflex: Medications like dextromethorphan and benzonatate are used to quiet a dry or irritating cough by acting on the brain or nerves.

  • Expectorants help with productive coughs: Guaifenesin is an expectorant that thins mucus, making a wet cough more effective at clearing airways.

  • Match the medicine to the cough: Choose a suppressant (dextromethorphan) for a dry cough or an expectorant (guaifenesin) for a wet cough.

  • Be aware of prescription options and risks: Stronger medications like benzonatate and codeine are available by prescription but carry significant safety warnings and side effects.

  • Consider combination products carefully: Many multi-symptom cold medicines exist; ensure the ingredients target only your active symptoms to minimize risks.

  • Natural remedies offer soothing relief: Home remedies such as honey, steam, and proper hydration can help ease a cough naturally.

  • Seek medical advice for persistent coughs: If your cough lasts for weeks or is accompanied by other serious symptoms, consult a healthcare provider.

In This Article

Understanding the Different Types of Cough Medications

When seeking relief for a cough, it's crucial to first determine the type of cough you have. Coughs are generally categorized into two types: a dry, non-productive cough and a wet, productive cough. The medication you choose should align with your specific symptoms to be most effective.

Antitussives: Suppressing the Cough Reflex

Antitussives are medications designed to suppress the urge to cough by acting on the cough center in the brain. They are most effective for dry, hacking coughs that don't produce mucus and can interrupt sleep. The most common over-the-counter (OTC) antitussive is dextromethorphan.

Dextromethorphan (DM)

  • How it works: Dextromethorphan (DM) is a synthetic analogue of codeine that works centrally to elevate the cough threshold. It does not have the same addictive properties as opioids when used at recommended doses.
  • Common brands: Delsym, Robitussin DM, and Mucinex DM (often in combination products) contain dextromethorphan.
  • Use cases: Best for dry coughs caused by minor throat and bronchial irritation, such as from the common cold or flu.

Expectorants: Loosening and Thinning Mucus

Expectorants, on the other hand, are for wet or productive coughs where you are bringing up mucus. Their purpose is not to stop the cough but to make it more effective in clearing the airways. Guaifenesin is the only FDA-approved OTC expectorant.

Guaifenesin

  • How it works: Guaifenesin works by thinning and loosening the mucus in the lungs and airways. This makes it easier to clear phlegm through coughing, relieving chest congestion.
  • Important note: It is crucial to drink plenty of fluids while taking guaifenesin to help the thinning process.
  • Common brands: Mucinex, Robitussin Chest Congestion, and many combination products.

Prescription Options: For Severe and Persistent Coughs

When OTC medications are not sufficient, a doctor may prescribe a stronger cough treatment. These are typically reserved for more severe or chronic coughs.

Benzonatate (Tessalon Perles)

  • How it works: Benzonatate is a non-narcotic prescription cough suppressant that acts peripherally by anesthetizing the stretch receptors in the lungs and airways. This reduces the cough reflex at its source.
  • Important warnings: The capsules must be swallowed whole, as chewing or sucking them can cause dangerous and life-threatening reactions, including local anesthesia of the mouth and throat, potentially leading to choking or laryngospasm.
  • Safety concerns: There are significant safety concerns regarding accidental ingestion by children, which can be fatal.

Opioid-Based Medications (Codeine, Hydrocodone)

  • How they work: Opioid agonists like codeine and hydrocodone are potent cough suppressants that act on the brain's cough center.
  • Serious risks: These carry risks of sedation, respiratory depression, and dependence. The FDA has restricted their use in children and adolescents under 18 due to these concerns.

Comparison of Common Cough Medications

Feature Dextromethorphan (DM) Benzonatate (Tessalon) Guaifenesin (Mucinex) Codeine/Hydrocodone
Category Antitussive (Suppressant) Antitussive (Suppressant) Expectorant Antitussive (Suppressant)
Cough Type Dry, non-productive Severe, persistent Wet, productive Severe, dry (last resort)
Availability Over-the-Counter Prescription Only Over-the-Counter Prescription Only
Primary Mechanism Acts centrally on the brain to raise cough threshold Acts peripherally by numbing respiratory tract stretch receptors Thins and loosens mucus for easier expectoration Acts centrally on the brain's cough center; opioid effects
Key Risks Drowsiness, dizziness, nausea. Abuse potential at high doses Fatal overdose if chewed or ingested by children; sedation, confusion Nausea, vomiting. Few significant risks at recommended doses Sedation, respiratory depression, constipation, dependence

How to Choose the Right Pill to Stop Coughing

Choosing the correct medication requires a careful assessment of your symptoms and health history.

1. Identify your cough type: Is it dry and hacking, or wet and productive? If it's a dry cough, an antitussive like dextromethorphan may be appropriate. If it's wet with mucus, an expectorant like guaifenesin is a better choice.

2. Read labels for combination products: Many OTC cold and flu medications contain multiple active ingredients, such as a suppressant, expectorant, decongestant, and pain reliever. Avoid taking medications for symptoms you don't have to minimize side effects.

3. Consider non-medicinal remedies: For mild coughs, a warm beverage with honey and lemon can be soothing. A cool-mist humidifier can also help relieve a dry, irritating cough.

4. Consult a healthcare provider: If your cough is severe, persistent, or accompanied by other concerning symptoms, such as fever, chest pain, or shortness of breath, consult a doctor. Never stop taking prescribed medication without a doctor's advice.

Conclusion: The Right Medication for the Right Cough

There is no single definitive pill that stops coughing for everyone. Effective treatment depends on matching the right medication to the type of cough you are experiencing. Over-the-counter options like dextromethorphan for dry coughs and guaifenesin for wet coughs are readily available. For severe cases, a healthcare provider might prescribe benzonatate or, in rare instances, a controlled substance like codeine. Always read labels carefully, follow dosage instructions, and seek professional medical advice for persistent or severe symptoms to ensure safe and effective relief. For more information on drug safety, visit MedlinePlus.

Frequently Asked Questions

For a dry, non-productive cough, an over-the-counter antitussive containing dextromethorphan (DM) is often recommended. This medication helps to suppress the cough reflex in the brain.

For a wet or productive cough with mucus, an expectorant like guaifenesin is a better choice. It works by thinning the mucus, making it easier to cough up and clear your airways.

Cough suppressants, such as dextromethorphan, can help quiet a dry cough that keeps you awake. Some nighttime products also include an antihistamine that can cause drowsiness.

Benzonatate (brand name Tessalon Perles) is a prescription non-opioid cough suppressant that works by numbing the stretch receptors in your lungs and airways. It is used for severe coughs and has specific safety warnings.

Combination products containing both a suppressant (dextromethorphan) and an expectorant (guaifenesin) are common, such as Mucinex DM. However, using a suppressant for a productive cough can hinder the body's natural clearing process.

Yes, for mild coughs, especially at night, honey can be very effective and soothing. It is not recommended for children under one year old due to the risk of botulism.

You should see a doctor if your cough lasts more than a week, is severe, or is accompanied by fever, chest pain, wheezing, or bloody phlegm.

The American Academy of Family Physicians advises against giving OTC cough medicines to children under 6 due to potential risks and lack of proven effectiveness. Natural remedies like honey (for children over one) and hydration are safer alternatives.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.