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What is the price of amoxicillin 500mg? A guide to costs and savings

4 min read

Generic amoxicillin is one of the most widely prescribed and generally affordable antibiotics, and the cash price for a standard course of amoxicillin 500mg can range from as little as $4 to over $30 without insurance, depending heavily on where you shop and if you use a discount program. Understanding the various factors that influence this price can help you secure the best deal.

Quick Summary

The price for a standard course of 21 amoxicillin 500mg capsules typically ranges from $4 to over $30 without insurance. Factors like pharmacy, location, discount programs, and insurance status significantly influence the final cost.

Key Points

  • Price Variability: The cost of amoxicillin 500mg without insurance can range significantly, typically between $4 and $30 for a standard treatment, depending on factors like pharmacy and location.

  • Generic is Cheaper: Always opt for the generic amoxicillin over the brand-name Amoxil to secure a much lower price.

  • Use Discount Programs: Free coupons from services like GoodRx, SingleCare, and BuzzRx can dramatically lower your out-of-pocket cost, sometimes beating insurance co-pays.

  • Compare Pharmacies: Prices are not uniform across retailers. Comparing prices at different pharmacies, including major chains and local stores, can result in significant savings.

  • Explore Mail-Order Options: Online pharmacies, such as Mark Cuban's Cost Plus Drugs and Amazon Pharmacy, can offer competitive pricing and convenience through home delivery.

  • Check Generic Lists: Some retail chains, like Walmart, offer 30-day supplies of generic amoxicillin for as little as $4 as part of their discount lists.

In This Article

Understanding the Cash Price Without Insurance

For those without insurance or whose insurance co-pay is higher than the cash price, the retail cost for amoxicillin can vary dramatically. In 2025, the average retail price for a typical 10-day course (21 capsules of 500mg) is around $11-$12 at many pharmacies. However, this is just an average, and you can find substantially lower prices by using specific strategies. Discount cards from services like GoodRx can bring the price down to as low as $8.10 or even lower at some locations. Mail-order pharmacies, such as Mark Cuban's Cost Plus Drugs, can offer 30 tablets for approximately $7, plus a shipping fee. Comparing costs across different sources is essential to finding the most affordable option.

Key Factors That Influence the Cost

The price you pay for amoxicillin 500mg is not a fixed number. Multiple variables contribute to the final cost:

  • Pharmacy: Prices can differ by as much as $25 between different pharmacy chains due to varying wholesale discounts and mark-up strategies. Big-box retailers like Walmart often have lower prices, with some appearing on their generic lists for as little as $4 for a 30-day supply.
  • Location: Geographic location plays a role, with studies showing that retail drug prices can be higher in rural or less competitive areas. Local demand and cost of living can also influence pricing.
  • Insurance Coverage: For those with insurance, the out-of-pocket cost is determined by their plan's co-pay, deductible, and formulary. The co-pay for generic amoxicillin is typically low, often between $0 and $10, but it is important to compare this with cash prices and coupon costs, as sometimes the latter can be lower.
  • Dosage and Formulation: While this article focuses on the 500mg capsule, different strengths or formulations, such as liquid suspensions for children, will have different price points. Liquid versions are generally more expensive.
  • Quantity: The total cost is directly related to the number of capsules prescribed. A longer treatment plan will result in a higher overall price.
  • Generic vs. Brand Name: The brand name, Amoxil, typically costs much more than the generic amoxicillin, despite having the same active ingredient. Always ask for the generic version to maximize savings.

Price Comparison for Amoxicillin 500mg

Source/Pharmacy Type Est. Cash Price (21 x 500mg capsules) Notes
GoodRx (Coupon) Coupon As low as $8.10 Varies by pharmacy and location. Requires coupon.
Walmart Retail/Generic List $4 (for a 30-day supply) Price may vary by location. Part of generic list.
Cost Plus Drugs Mail-Order ~$7 + shipping (for 30 tablets) Price is for 30 tablets and does not include shipping.
CVS Retail ~$15-$30 Walk-in price. Can vary.
Walgreens Retail ~$15-$35 Walk-in price. Can vary.
SingleCare (Coupon) Coupon ~$3-$12 Varies by pharmacy. Requires coupon.

8 Ways to Save Money on Amoxicillin 500mg

  1. Use Discount Coupons: Services like GoodRx, SingleCare, and BuzzRx offer free coupons that can be shown to your pharmacist for a significant discount. Prices with coupons are often lower than average retail prices.
  2. Compare Pharmacy Prices: Always check prices at different pharmacies in your area. Use online tools or apps from discount services to quickly compare cash prices before you fill your prescription.
  3. Use Mail-Order Pharmacies: Online pharmacies like Mark Cuban's Cost Plus Drugs or Amazon Pharmacy often have lower overhead and can pass those savings on to you. They may offer even better prices than local retailers.
  4. Buy Generic: The brand name drug Amoxil is typically much more expensive. Ensure your doctor or pharmacist knows you want the generic amoxicillin to save money.
  5. Look for a $4 Generic List: Some major retailers like Walmart have a list of common generic medications available for a very low price. Check if amoxicillin is on their list at your local store.
  6. Join Store Savings Clubs: Memberships at stores like Costco or Kroger can unlock lower prices on generic prescriptions through their respective programs.
  7. Check Patient Assistance Programs (PAPs): While generic amoxicillin is inexpensive, non-profit organizations like NeedyMeds or manufacturer programs might offer assistance for those with low income.
  8. Use HSA or FSA Funds: If you have a Health Savings Account or Flexible Spending Account, you can use these tax-advantaged funds to pay for your prescription.

Insurance Coverage vs. Discount Programs

For many, insurance coverage provides the easiest and most cost-effective way to get amoxicillin. However, there are scenarios where a discount coupon might be a better option:

  • High Deductible Plan: If you haven't met your annual deductible, your out-of-pocket cost might be higher than a coupon price. You can ask the pharmacist to run the prescription with and without insurance to see which offers the best deal.
  • High Co-pay: Occasionally, a discount coupon might offer a lower price than your standard co-pay, especially for inexpensive generic drugs. Checking coupon sites is a quick and easy way to compare.
  • No Coverage: If you are uninsured, discount coupons and pharmacy generic lists are your best tools for finding an affordable price.

It is important to remember that using a discount coupon typically means the purchase will not count towards your annual deductible, but for a low-cost medication like amoxicillin, this is often a minor consideration.

Conclusion: Finding the Best Price

The price of amoxicillin 500mg can vary significantly based on your insurance status, your choice of pharmacy, and whether you use discount programs. While the average cash price for a standard course is relatively low, savvy shoppers can find prices at the lowest end of the spectrum by comparing options. Utilizing free coupons from online aggregators, checking generic lists at large retailers, and exploring mail-order pharmacy options are all effective strategies to ensure you get the best possible price. By taking a few extra steps, you can save money without compromising on the quality or effectiveness of your medication.

Frequently Asked Questions

Without insurance, the cash price for a 10-day course (21 capsules) of amoxicillin 500mg can vary. Averages hover around $11-$12, but with discount coupons or at specific pharmacies like Walmart, the cost can be as low as $4 to $8.

Yes, for inexpensive generic drugs like amoxicillin, a discount coupon from services like GoodRx can sometimes offer a lower price than your insurance co-pay. It is always wise to check both options.

Yes, prices can differ significantly between pharmacies due to different pricing policies and wholesale purchasing power. It is highly recommended to compare prices at multiple pharmacies, as well as online, to find the best deal.

Yes, mail-order pharmacies, including insurance-affiliated ones and independent services like Mark Cuban's Cost Plus Drugs, often have lower overhead and can provide more affordable prices, especially for generic medications.

Generic amoxicillin is substantially less expensive than the brand-name version, Amoxil, while containing the same active ingredient. Always ask for the generic to maximize your savings.

Yes, beyond discount coupons, you can look into Patient Assistance Programs (PAPs) offered by drug manufacturers or non-profit organizations. For those with low income, federally qualified health centers may also offer discounted prices.

Yes, buying a larger quantity, such as a 90-day supply instead of a 30-day supply, can often reduce the cost per capsule. This is a common strategy for saving money on long-term medications.

Publix ended its free prescription program on June 1, 2022. While no longer free, generic medications including amoxicillin are now available for a low cost, such as $7.50 for a 14-day supply.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.