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What is the tablet that pilots use? Understanding the Pharmacology of 'Go Pills' and Strict FAA Rules

5 min read

In a 2011 study, 42% of fatal aviation accidents involving pilots tested positive for drugs or medications, most often over-the-counter types. This statistic underscores the strict regulations governing what is the tablet that pilots use and highlights the significant distinction between military and civilian aviation pharmacology.

Quick Summary

The idea of a single tablet that pilots use is a misconception. Military aviators may use prescription 'go pills' and 'no-go pills' for fatigue management, while civilian pilots operate under highly restrictive FAA rules that prohibit stimulants and limit many other substances.

Key Points

  • Different Rules: Military and civilian pilots operate under fundamentally different rules regarding medication, with military aviators permitted controlled use of specific stimulants and sleep aids under strict protocols.

  • Military 'Go' and 'No-Go' Pills: Military personnel on long missions may use 'go pills' (e.g., Modafinil, Dextroamphetamine) to combat fatigue and 'no-go pills' (e.g., Zolpidem, Temazepam) for scheduled rest.

  • FAA Prohibition for Civilian Pilots: The FAA strictly prohibits civilian pilots from using stimulants and most sedating medications due to safety concerns, and the underlying condition may also be disqualifying.

  • Strict Oversight and Ground-Testing: All military use of these pharmacological agents is supervised by a flight surgeon and requires prior 'ground-testing' to assess individual reactions.

  • Non-Pharmacological Focus: Both military and civilian protocols emphasize exhausting non-medication strategies (rest, scheduling) for managing fatigue before considering medication.

  • Risk of OTC Medications: Over-the-counter medications, including sedating antihistamines, can impair pilot performance and are restricted by the FAA.

  • Caution with New Medications: The FAA recommends a 48-hour wait after taking any new medication for the first time to ensure no adverse side effects occur.

In This Article

The concept of a single "tablet that pilots use" is a common point of public curiosity, often sensationalized in media or misunderstood in context. In reality, the world of aviation medicine is complex and highly regulated, with stark differences between military and civilian protocols. The medication, if any, that an aviator is permitted to take is not a performance-enhancing boost, but a carefully managed safety countermeasure, or, in the case of civilian pilots, an off-limits substance entirely.

The Myth of a Single Pill

Unlike an over-the-counter remedy that a person might take for a headache, pilots' use of medication is not a casual decision. The question of what pilots can take is less about what they do take and more about what they are allowed to take under highly controlled circumstances. For military pilots, this involves specific stimulants and sedatives used to manage fatigue during combat operations. For civilian pilots, Federal Aviation Administration (FAA) regulations are so strict that most medications carrying a warning about operating machinery are prohibited, even if the user feels no side effects.

Military Aviation: Controlled Use of 'Go' and 'No-Go' Pills

Military pilots, particularly those involved in long-endurance missions and combat operations, operate under protocols developed to combat severe fatigue and circadian rhythm disruption. In these situations, sleep deprivation is often unavoidable, necessitating pharmacological countermeasures. The use of these medications is not a casual practice but is governed by strict protocols and supervised by a flight surgeon.

Approved Stimulants

To help maintain alertness and performance, military aviators may use "go pills," which are stimulants. The two primary medications are Modafinil (brand name Provigil) and Dextroamphetamine (brand name Dexedrine).

  • Modafinil: This wakefulness-promoting drug has been shown to be effective in sustaining alertness and improving cognitive function in sleep-deprived individuals. It is often preferred over older stimulants due to its lower abuse potential and less disruptive effect on subsequent sleep.
  • Dextroamphetamine: Historically used by the military, Dextroamphetamine is a stronger stimulant that is also effective in maintaining alertness and performance. Its use is typically more strictly controlled than Modafinil.

Approved Sleep Aids

After a long mission on stimulants, military pilots may require assistance in getting a full night's rest to reset their internal clock. For this purpose, they may use "no-go pills," which are sedatives.

  • Approved Sedatives: Common examples include Zolpidem (Ambien), Temazepam (Restoril), and Zaleplon (Sonata).
  • Ground-Testing: All military aircrew members are required to undergo a "ground-test" for these medications before operational use. This ensures they do not have any adverse reactions and can perform normally after the drug's effects have worn off.

Civilian Aviation: Navigating Strict FAA Regulations

In stark contrast to military practice, civilian pilots are subject to stringent regulations from the Federal Aviation Administration (FAA). The primary guiding principle is flight safety, which can be degraded by both the medication itself and the underlying medical condition requiring treatment. The FAA generally prohibits the use of most psychoactive medications, especially those that can cause sedation or impair cognitive function.

FAA Prohibition of Performance-Enhancing Drugs

According to Federal Aviation Regulations (FAR) 61.53 and 91.17, a pilot cannot fly if they know they have a medical condition or are taking medication that could compromise safety. This means that civilian pilots cannot use stimulants like Modafinil or Dextroamphetamine. It is also important to remember that these rules are designed to protect against both the drug's effects and the condition it's treating.

The 48-Hour and Five-Dosing-Interval Rule

The FAA has specific guidelines regarding the use of new medications. Pilots should never fly after taking any new medication for the first time until at least 48 hours have passed and they have confirmed no adverse side effects. For potentially sedating over-the-counter medications, the wait time is even longer: five times the maximum dosage interval.

Over-the-Counter Medication Risks

Many seemingly innocuous over-the-counter (OTC) remedies, such as antihistamines and some cough syrups, contain sedating ingredients like diphenhydramine. These can have a lingering effect, or "hangover," that impairs a pilot's performance and is a documented risk factor in general aviation accidents.

Non-Pharmacological Fatigue Management

Civilian aviation relies heavily on non-pharmacological methods to combat fatigue, such as regulated rest periods, strategic nap opportunities during long-haul flights, and optimized flight schedules. Healthy lifestyle choices, including proper diet and exercise, are strongly encouraged as the primary line of defense.

Military vs. Civilian Pilot Medication Comparison

Feature Military Pilot (Under Operational Orders) Civilian Pilot (FAA Regulated)
Stimulant Use Permitted under strict flight surgeon supervision for specific missions. Prohibited. Considered a disqualifying substance due to safety risks.
Sedative Use Permitted under flight surgeon supervision to ensure restful sleep (e.g., "no-go pills"). Prohibited while on flight duty. The underlying condition requiring sleep aid may also be disqualifying.
Approval Process Requires commander and flight surgeon approval, including ground-testing. All medication and underlying conditions must be reported to an Aviation Medical Examiner (AME).
Oversight Monitored by a flight surgeon, with ground-testing of reactions. Self-monitoring is required. Pilots must ground themselves if taking a medication that could impair faculties.
Primary Fatigue Management Exhausts non-pharmacological methods first; medication is a last resort. Relies exclusively on non-pharmacological methods like controlled rest and optimized scheduling.
OTC Medication Restricted. All medications must be cleared by a flight surgeon. Many common OTC drugs (e.g., sedating antihistamines) are prohibited due to side effects.

The Importance of Ground-Testing and Physician Consultation

Whether in the military or civilian sector, the principle of testing one's reaction to medication is paramount. For military aviators, this is a formal ground-testing protocol, while for civilians, it is a personal responsibility to ensure no adverse effects exist before flying. Ultimately, a pilot should always consult with an Aviation Medical Examiner (AME) to determine if a condition or treatment is compatible with safe flight.

Conclusion

The notion of a single "tablet that pilots use" is a vast oversimplification of a highly regulated aspect of aviation. While military pilots, under specific operational duress, may use controlled stimulants and sedatives, civilian pilots are governed by strict FAA rules that prohibit such substances due to their potential to impair judgment and compromise safety. The cornerstone of aviation pharmacology is the exhaustive management of fatigue through non-pharmacological means first, with medication only entering the equation under rigorous, medically supervised protocols in the military, and with severe restrictions for civilian airmen. For civilian pilots, safety demands abstaining from a wide range of medications and understanding that their underlying medical condition is just as important as the medication prescribed to treat it.

For further details on FAA regulations regarding medications, visit the Aircraft Owners and Pilots Association (AOPA) website.

Frequently Asked Questions

For military pilots, yes, under strict medical supervision and for specific operational needs. For civilian pilots, no, the FAA prohibits the use of stimulants and has strict rules against flying while using most medications that affect safety.

'Go pills' are stimulants like Modafinil or Dextroamphetamine used by military pilots to maintain alertness during prolonged missions. 'No-go pills' are sedatives like Zolpidem or Temazepam used to ensure restful sleep before a mission.

Due to the unique demands of combat and extended operations that disrupt normal sleep cycles, the military has approved the highly controlled use of stimulants for maintaining performance in critical, high-stakes situations.

The FAA warns against this. Many common cold remedies contain sedating ingredients that can impair judgment. Pilots should not fly while taking medications that cause drowsiness and must observe a waiting period.

The FAA recommends that pilots wait at least 48 hours after taking any new medication for the first time before flying. This allows them to monitor for any unexpected adverse side effects while on the ground.

If a pilot experiences any side effects from a medication, even one typically allowed by the FAA, they are prohibited from flying. They must also report any adverse reactions to their supervisor and flight surgeon.

Pilots primarily rely on non-pharmacological methods for fatigue management, such as proper rest, strategic naps, adherence to duty time limits, and a healthy diet and exercise.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.