Understanding the Angela 35 Tablet: Active Ingredients and Mechanism
Angela 35 Tablet combines two hormonal medicines: cyproterone acetate and ethinyl estradiol. Cyproterone acetate is an anti-androgen that blocks androgen receptors, reducing the effects of male hormones responsible for symptoms like excessive hair growth and acne. Ethinyl estradiol, a synthetic estrogen, supports the anti-androgenic action by increasing SHBG, which binds to androgens. It also helps regulate the menstrual cycle.
Primary Medical Uses of Angela 35 Tablet
Polycystic Ovary Syndrome (PCOS)
Angela 35 Tablet is primarily used to manage symptoms of Polycystic Ovary Syndrome (PCOS), a condition with high androgen levels. Key symptoms treated include excessive hair growth (hirsutism), irregular periods, and severe acne.
Severe Hormonal Acne
The tablet effectively treats moderate to severe acne linked to androgen sensitivity, especially when other treatments fail. It reduces oil production, clearing existing acne and preventing new outbreaks. Improvement is typically seen within a few months.
Contraceptive Action
While Angela 35 Tablet is a highly effective contraceptive by inhibiting ovulation, it is not prescribed solely for birth control due to its specific hormonal profile and risks. Users should not use additional hormonal contraceptives.
Comparison: Angela 35 vs. Standard Oral Contraceptives
| Feature | Angela 35 Tablet | Standard Oral Contraceptive (e.g., Ethinyl Estradiol/Levonorgestrel) |
|---|---|---|
| Primary Indication | Androgen-related conditions (PCOS, severe acne, hirsutism). | Primarily for contraception. |
| Active Ingredients | Cyproterone Acetate and Ethinyl Estradiol. | Ethinyl Estradiol and another progestin (e.g., Levonorgestrel, Norgestimate). |
| Anti-androgenic Effect | Strong anti-androgenic effect due to cyproterone acetate. | Weaker or no anti-androgenic effect, depending on the progestin. |
| Efficacy for Acne/Hirsutism | High efficacy specifically for androgen-sensitive acne and excessive hair growth. | Variable, generally less effective for treating severe androgenic symptoms compared to Angela 35. |
| Risk Profile (Blood Clots) | Increased risk of blood clots, particularly higher than with some standard oral contraceptives, and should not be used just for birth control. | General risk of blood clots, but often lower than anti-androgen combinations. |
Potential Side Effects and Precautions
Angela 35 Tablet can cause side effects. Common ones like nausea, headache, weight gain, breast pain, mood changes, and breakthrough bleeding usually improve over time.
Serious risks include an increased risk of blood clots (VTE), especially with risk factors like obesity or smoking. Rarely, it can cause liver problems or increase blood pressure. Signs of serious issues require immediate medical attention.
Contraindications and Considerations
Angela 35 Tablet is not suitable for everyone. It should not be used during pregnancy or breastfeeding, or by individuals with a history of blood clots, stroke, heart attack, severe liver disease, certain migraines, or estrogen-sensitive cancers. Obesity and smoking, especially in women over 35, also contraindicate its use.
Conclusion
Angela 35 Tablet is a targeted hormonal medication for women with androgen-sensitive conditions such as moderate to severe acne, hirsutism, and PCOS. While it also provides contraception, it is not recommended for this purpose alone due to its higher risk profile. The combination of cyproterone acetate and ethinyl estradiol effectively addresses androgen-related symptoms and regulates the menstrual cycle. A thorough discussion of medical history and risks with a doctor is crucial before starting treatment. For detailed information, consult {Link: Truemeds https://www.truemeds.in/drug-salts/cyproterone-ethinyl-estradiol-10519}.
