What is Dios Tablet?
Dios Tablet is a phlebotonic agent, which means it is a drug used to improve the health of veins. It is most commonly composed of a micronized purified flavonoid fraction (MPFF), which includes about 90% diosmin and 10% hesperidin. These active ingredients are bioflavonoids, which are plant chemicals naturally found in citrus fruits. Diosmin was first isolated in 1925 and has been used therapeutically since 1969 as a vascular-protecting agent. The micronization process reduces the particle size of the compounds, which can lead to better absorption and bioavailability. While available as a dietary supplement in the United States, it is prescribed as a medication in many European countries.
Mechanism of Action: How Does It Work?
The effectiveness of Dios Tablet stems from its multi-faceted mechanism of action on the circulatory system. The combination of diosmin and hesperidin works synergistically to:
- Improve Venous Tone: It enhances the strength and elasticity of blood vessels and prolongs the vasoconstrictor effect of norepinephrine on the vein walls. This action reduces venous stasis, the pooling of blood in the veins.
- Reduce Inflammation: The flavonoids have anti-inflammatory properties that inhibit inflammatory messengers. This helps reduce swelling, pain, and discomfort associated with venous disorders.
- Enhance Lymphatic Drainage: It improves lymphatic flow by decreasing intralymphatic pressure, which helps reduce edema (swelling caused by excess fluid).
- Support Capillary Health: The tablet strengthens capillary walls and normalizes their permeability, which helps prevent leakage and fragility that can lead to skin changes or ulcers.
Primary Uses of Dios Tablet
Due to its effects on blood vessels, Dios Tablet is primarily indicated for two main conditions:
Chronic Venous Insufficiency (CVI)
CVI occurs when the veins in the legs are unable to efficiently send blood back to the heart, leading to blood pooling. Dios Tablet is effective in managing CVI symptoms, which include:
- Varicose veins
- Leg pain and heaviness
- Swelling (edema)
- Nighttime cramps
- Skin changes and venous ulcers
Studies have shown that treatment with diosmin can lead to a significant reduction in leg circumference and pain intensity in patients with CVI. While it helps manage symptoms and improve quality of life, it is not a permanent cure for varicose veins, which may require procedural intervention for complete removal.
Hemorrhoidal Disease
Hemorrhoids are swollen veins in the lower rectum and anus. Dios Tablet is widely used for both acute hemorrhoid attacks and long-term management. It helps alleviate symptoms such as pain, bleeding, itching, and discharge. For acute episodes, the administration may involve varying quantities over a specified period.
Dosage and Administration
The appropriate administration depends on the condition being treated and should always be determined by a healthcare professional. It is generally recommended to take the tablet with meals to improve absorption and minimize potential gastrointestinal discomfort.
Potential Side Effects and Precautions
Dios Tablet is generally well-tolerated, with most side effects being mild and infrequent. The most common adverse reactions include:
- Abdominal pain
- Nausea
- Diarrhea
- Headache
There is insufficient data on its safety during pregnancy and breastfeeding, so it should be avoided unless recommended by a doctor. Patients with bleeding disorders or those taking anticoagulant (blood-thinning) medications should consult their doctor, as diosmin might slow blood clotting and increase the risk of bleeding.
Dios Tablet vs. Other Treatments for CVI
| Treatment Option | Invasiveness | Typical Use Case | Key Benefit |
|---|---|---|---|
| Dios Tablet | Non-invasive (Oral) | Mild to moderate CVI symptoms, leg heaviness, pain, edema. | Systemic oral therapy, improves vein tone and reduces inflammation. |
| Compression Stockings | Non-invasive (External) | All stages of CVI, prevention, post-procedure care. | Provides external pressure to aid blood flow, reduces swelling. |
| Lifestyle Changes | Non-invasive (Behavioral) | Foundational for all CVI patients. | Leg elevation, exercise, and weight management can reduce venous pressure. |
| Sclerotherapy | Minimally invasive | Spider veins and small varicose veins. | Injects a solution to close targeted veins. |
| Vein Ablation/Surgery | Invasive | Severe varicose veins, significant reflux. | Permanently removes or closes the malfunctioning vein. |
Conclusion
Dios Tablet, a formulation of the flavonoids diosmin and hesperidin, serves as an effective oral therapy for managing the symptoms of chronic venous insufficiency and hemorrhoidal disease. By improving venous tone, reducing inflammation, and supporting microcirculation, it provides significant relief from pain, swelling, and other discomforts associated with these vascular conditions. Although generally safe, it is essential to use this supplement under the guidance of a healthcare professional to ensure appropriate administration and to avoid potential interactions, especially for individuals with pre-existing conditions or those taking other medications.
For more in-depth scientific information, you can review this article from the National Institutes of Health: Potential and Therapeutic Roles of Diosmin in Human Diseases
Disclaimer: This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare professional before starting any new supplement regimen.
