What is Zidoval and How Does It Work?
Zidoval is a brand name for a vaginal gel containing the antibiotic metronidazole. It's primarily used to treat bacterial vaginosis (BV), a vaginal infection caused by an overgrowth of anaerobic bacteria. Zidoval is applied directly to the vagina, delivering the antibiotic locally to fight the infection.
Metronidazole, the active ingredient, is a nitroimidazole antibiotic that disrupts bacterial DNA, preventing bacterial growth and eliminating the microorganisms causing BV. This helps restore the natural balance of vaginal bacteria and alleviates symptoms like abnormal discharge and odor. The topical application means less medication is absorbed into the bloodstream, potentially reducing systemic side effects compared to oral treatments.
How to Use Zidoval Vaginal Gel
Effective use of Zidoval requires following specific instructions. The gel includes single-use applicators for hygienic and accurate dosing. The typical treatment is one applicatorful daily, usually at bedtime, for five days.
Application steps include:
- Washing hands before use.
- Attaching an applicator to the tube and squeezing to fill it with a 5g dose.
- Lying down and gently inserting the applicator into the vagina.
- Pushing the plunger to release the gel.
- Disposing of the applicator after use.
It is recommended to use a panty liner for potential leakage and avoid tampons. Completing the full five-day course is essential to ensure the infection is fully treated and reduce the risk of recurrence.
Zidoval vs. Oral Metronidazole: A Comparison
Both Zidoval and oral metronidazole treat bacterial vaginosis but differ in administration and effects.
| Feature | Zidoval (Topical Gel) | Oral Metronidazole Tablets |
|---|---|---|
| Administration | Applied intravaginally. | Swallowed orally. |
| Dosage | 5g once daily for 5 days. | Typically 500mg twice daily for 7 days. |
| Systemic Absorption | Low. | High. |
| Common Side Effects | Local irritation, headache, nausea. | Metallic taste, nausea, vomiting, stomach cramps. |
| Alcohol Interaction | Avoid for at least 24 hours after treatment. | Strong adverse reaction. |
| Site of Action | Localized in the vagina. | Systemic. |
Common Side Effects and Contraindications
Zidoval is generally well-tolerated, with side effects often localized and milder than oral metronidazole.
Potential common side effects:
- Vaginal irritation, burning, or itching
- Headache
- Nausea and stomach cramps
- Unusual taste or furry tongue sensation
- Vaginal thrush (yeast infection)
Do not use Zidoval if you are allergic to metronidazole or other nitroimidazoles, or any of the gel's ingredients. Consult a doctor if you have blood or central nervous system disorders.
Important Precautions and Advice
Always inform your doctor about your medical history and current medications before using Zidoval.
Possible Interactions: Zidoval may interact with certain medications like blood thinners and lithium. Consult with your doctor about potential interactions.
Pregnancy and Breastfeeding: Discuss using Zidoval with a healthcare provider if pregnant or breastfeeding. It should only be used if medically recommended.
Sexual Activity: Avoid sexual intercourse during treatment and until the infection is cleared. Avoid using tampons.
Recurrence: BV can recur. If symptoms return, see a doctor. For more information on BV treatment, refer to resources like the CDC's STI Treatment Guidelines.
Conclusion
Zidoval is an effective prescription gel for bacterial vaginosis, delivering the antibiotic metronidazole directly to the infection site to eliminate harmful bacteria and restore vaginal flora. It offers a topical alternative to oral antibiotics, potentially with fewer systemic side effects. Following dosage instructions, completing the full course, and being aware of potential interactions are important. Always consult a healthcare professional for diagnosis and treatment advice.
