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What medication is Elon Musk using? A Closer Look at His Prescriptions and Reported Substance Use

4 min read

In a March 2024 interview, Elon Musk publicly disclosed that he has a prescription for ketamine to treat depression. The question of what medication is Elon Musk using has generated significant public interest and scrutiny, particularly regarding reports of additional substance use and conflicts with his companies' policies.

Quick Summary

Elon Musk has acknowledged using prescription ketamine for depression, though multiple reports allege he has used it and other substances more frequently and for recreational purposes. Concerns exist regarding this drug use and his corporate and governmental responsibilities. The reports contrast with Musk's public denials and shared drug test results.

Key Points

  • Prescription Ketamine: Elon Musk has a confirmed prescription for ketamine, which he uses to treat depression.

  • Broader Substance Use Allegations: Multiple reports from investigative journalists allege he uses illicit substances, including ecstasy and psychedelic mushrooms, in addition to ketamine.

  • Conflicting Narratives: Musk's statements and shared drug tests often conflict with media reports that claim more intense and frequent substance use, sometimes mixing drugs.

  • Corporate and Regulatory Scrutiny: Concerns about his drug use have been raised by executives at his companies and are relevant to SpaceX's government contracts and security clearances.

  • Associated Health Conditions: Musk has revealed he has Asperger's syndrome and has spoken about experiencing periods of depression and high stress.

  • Other Reported Medications: He has also publicly mentioned or been reported to use other medications, including Wegovy for weight loss and Ambien for sleep.

In This Article

Elon Musk's Stated Use of Ketamine for Depression

Elon Musk first publicly addressed his use of ketamine during a March 2024 interview with journalist Don Lemon. During the conversation, Musk confirmed he has a prescription for ketamine, administered under the supervision of a physician, to help manage what he described as a "negative chemical state in my brain," which he equated to depression. He portrayed his use as occasional, stating he takes a "small amount" about once every two weeks.

Musk has also used his social media platform, X, to advocate for ketamine as an alternative to traditional antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), which he claims can 'zombify' people. This public stance positioned him as a proponent of ketamine therapy, drawing further attention to his personal health choices and challenging conventional mental health treatment narratives.

Allegations of Broader and More Frequent Drug Use

Despite Musk's public portrayal of controlled, infrequent ketamine use, several investigative reports from major media outlets have painted a different picture. Citing anonymous sources close to the billionaire, these reports allege a more intense and frequent pattern of substance use. Reports from The Wall Street Journal and The New York Times claim that Musk has used illicit drugs such as LSD, ecstasy (MDMA), and psychedelic mushrooms at private parties. The Times further alleged that his ketamine use was more frequent than disclosed, at times nearing a daily habit, and that he even confessed to experiencing bladder issues, a known side effect of chronic ketamine use.

The Corporate and Governmental Implications

The reported drug use has raised significant concern among board members and executives at Musk's companies, including Tesla and SpaceX. As a major government contractor, SpaceX is required to maintain a drug-free workplace, and concerns were raised about the potential impact of Musk's alleged drug use on his security clearance and contracts. In response, Musk has denied the allegations and publicly posted drug test results, including one following a May 2025 New York Times report. However, sources have also alleged that Musk received advance warning of drug tests, undermining the validity of a negative result as proof of abstinence.

Contrasting Claims: A Comparison of Reported Substance Use

The public discourse surrounding Elon Musk's medication and substance use is often a study in contrasts. The following table summarizes the different claims reported in the media and from Musk himself.

Substance Elon Musk's Claims Media Reports & Sources Implications
Ketamine Prescription use for depression; small amount, occasionally (e.g., every two weeks). More frequent use, sometimes daily; used for recreation; caused bladder issues. Concerns about addiction and professional behavior; potential violation of controlled substance laws.
Psychedelics (Ecstasy, Mushrooms) Never publicly acknowledged use; denies widespread drug use. Used recreationally at private gatherings according to anonymous sources. Raises questions about judgment and safety, particularly concerning companies with federal contracts.
Adderall No public statement acknowledging use. Pills with Adderall markings were reportedly seen in his daily medication box. Potential for performance-enhancing effects; raises questions about medical supervision.
Ambien Admitted to taking the sleep medication in a 2018 interview. Concerns raised by board members about his use. Sleep-related side effects and potential for misuse; could affect daytime performance.
Weight-loss Medication (Wegovy) Publicly advocated for fasting and using Wegovy to stay fit. Confirmed by people familiar with his habits. Uncontroversial medication use, but reflects a broader pattern of reported medical interventions.

The Medical and Legal Context of Ketamine

From a medical perspective, it's important to distinguish between FDA-approved uses and off-label applications. While the FDA has approved esketamine, a derivative of ketamine, for treatment-resistant depression under strict clinical supervision, the general use of ketamine for depression remains largely unregulated. Off-label use, though legal under a doctor's care, carries risks and often requires careful monitoring, which may not align with reported unsupervised use. Chronic or heavy misuse of ketamine can lead to serious health problems, including cognitive impairment, memory issues, and urinary tract damage, which media reports suggest Musk experienced.

The Broader Picture of Elon Musk's Health

Beyond medication, Elon Musk's health profile includes other factors. He has publicly stated that he has Asperger's syndrome, a neurodevelopmental condition on the autism spectrum. He has also spoken about experiencing significant stress and mood swings. His history of admitted Ambien use for sleep, coupled with his promotion of ketamine and other reported lifestyle habits, paints a complex picture of a high-achieving individual using various methods to manage health challenges. It's a situation that combines legitimate medical concerns with public speculation and corporate scrutiny, amplified by his high-profile status.

Conclusion: A Contentious and Evolving Narrative

The question of what medication is Elon Musk using is complex and mired in controversy. While he has publicly acknowledged and even advocated for the use of prescription ketamine for depression, media reports from sources like The New York Times and The Wall Street Journal suggest a history of more extensive and recreational drug use. Musk has refuted these allegations, citing negative drug tests, but the conflicting accounts and concerns from company executives and government regulators persist. His disclosed Asperger's diagnosis, along with reported stress and anxiety, may provide context for his exploration of alternative mental health treatments. Ultimately, the full extent of his medication use remains a subject of debate, with his public statements and media reports offering vastly different narratives.

For more information on the distinctions between medical and recreational ketamine, visit the National Institute on Drug Abuse website.

Frequently Asked Questions

Yes, Elon Musk stated in a March 2024 interview that he has a prescription from a doctor for ketamine, which he uses to treat bouts of depression.

In addition to acknowledging his depression, Musk revealed during a 2021 appearance on Saturday Night Live that he has Asperger's syndrome.

Yes, investigative reports from sources like The New York Times and The Wall Street Journal have cited anonymous sources claiming Musk has used other substances, including ecstasy, psychedelic mushrooms, and marijuana, in private settings.

As the head of major corporations like Tesla and SpaceX, which has government contracts, his substance use raises concerns among board members and regulators about his judgment, reliability, and potential security risks.

Musk has publicly denied allegations of heavy drug use and, following a May 2025 report, posted a screenshot of a negative drug test on X. He has often criticized the media reports as dishonest.

Musk and his attorney have said he is regularly and randomly drug tested at SpaceX. However, reports have also suggested he received advance warning for some of these tests.

The FDA has approved a specific form of ketamine, esketamine nasal spray, for treatment-resistant depression in a clinical setting. General ketamine is used off-label for depression, which is legal but not FDA-approved for that specific use, and carries significant risks if not medically supervised.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.