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What medication is used to stop lactation after stillbirth?: A Guide to Pharmacological and Non-Drug Options

4 min read

A study found that stillbirth was the main reason for lactation inhibition in over 50% of patients who received Cabergoline for this purpose. Navigating the physical process of milk production after such a profound loss is often traumatic. Understanding what medication is used to stop lactation after stillbirth? can provide clarity during this difficult time. This guide explores the options available, focusing on medication and alternative methods.

Quick Summary

Cabergoline is a dopamine agonist prescribed to stop lactation after a stillbirth by inhibiting the hormone prolactin. This article details its potential effects, side effects, precautions, and alternative non-pharmacological methods for lactation suppression.

Key Points

  • Cabergoline is the preferred medication: Cabergoline is a dopamine agonist that inhibits prolactin to stop milk production and is generally favored over older medications due to a better safety profile.

  • Timing can be crucial: Dopamine agonists are often more effective when administered early after delivery to prevent the onset of lactation.

  • Older medication, Bromocriptine, is not recommended: Bromocriptine is an older dopamine agonist that has been largely withdrawn for lactation suppression due to its association with more severe cardiovascular and neurological side effects.

  • Medication is not for everyone: Dopamine agonists are contraindicated in women with uncontrolled hypertension, pre-eclampsia, and certain cardiovascular or psychiatric conditions.

  • Natural methods are an alternative: Non-pharmacological options like supportive bras, cold compresses, cabbage leaves, and expressing milk for comfort can help manage discomfort and gradually reduce milk supply.

  • Professional medical advice is essential: The decision to use medication or natural methods should always be made in consultation with a healthcare provider to ensure safety and account for individual circumstances.

In This Article

Navigating Lactation After Loss

After a stillbirth, a woman's body will still undergo the hormonal changes of postpartum. The placenta is delivered, causing a rapid drop in progesterone and estrogen, while prolactin—the hormone responsible for milk production—remains high. This often leads to milk production and breast engorgement, a physically and emotionally painful experience for a grieving mother. Lactation suppression is the medical process of stopping milk production and is a critical part of postpartum care after a stillbirth. The decision to suppress lactation is a personal one, and options range from medication to natural methods. Discussion with a healthcare provider is essential to determine the safest and most suitable approach based on a woman's individual health history and circumstances.

Cabergoline: The Preferred Medication

Cabergoline (brand name Dostinex) is a long-acting dopamine agonist that is the preferred pharmacological agent for lactation suppression in many countries. It works by mimicking the effect of dopamine, which naturally inhibits the release of prolactin from the pituitary gland. By directly stimulating the D2-dopamine receptors, Cabergoline effectively and quickly reduces prolactin levels, thereby preventing or suppressing milk production.

Administration The administration of Cabergoline depends on whether lactation has already been established and should always follow the guidance of a healthcare professional.

The Older Alternative: Bromocriptine

In the past, Bromocriptine was commonly used for lactation suppression. However, its use for this purpose has been withdrawn or heavily restricted in many countries, including the US, due to reports of rare but serious adverse effects.

Risks Associated with Bromocriptine

  • Cardiovascular Events: Studies have linked Bromocriptine use for lactation suppression to serious cardiovascular issues, such as heart attack, stroke, and hypertension.
  • Neurological and Psychiatric Effects: Rare but potentially serious side effects like seizures and psychiatric disturbances have been reported.
  • Poorer Tolerability: Cabergoline has been shown to have a more favorable side-effect profile and better tolerability than Bromocriptine in head-to-head trials.

Comparison of Pharmacological and Non-Pharmacological Methods

Feature Pharmacological Method (Cabergoline) Non-Pharmacological Method (Natural)
Effectiveness High, especially when started early. Variable; depends on individual and consistency.
Onset of Action Rapid, often within a day or two. Gradual, may take several days to a few weeks.
Physical Discomfort Minimizes or prevents severe engorgement and pain. Can cause significant breast engorgement, pain, and leakage.
Convenience Typically involves a short course of oral medication. Requires consistent self-management over a longer period.
Side Effects Potential for mild side effects like dizziness, nausea; rare serious risks exist. No systemic drug-related side effects; local discomfort possible.
Contraindications Avoided in cases of uncontrolled hypertension or pre-eclampsia. Generally safe for most women, but managing discomfort is key.

Non-Pharmacological Methods for Lactation Suppression

For women who prefer to avoid medication or for whom it is contraindicated, several non-drug options can help manage the symptoms of lactation suppression:

  • Supportive Bra: Wearing a firm, supportive bra, both day and night, can help reduce discomfort from engorgement.
  • Cold Compresses: Applying cold compresses or gel packs to the breasts for 15-20 minutes at a time can reduce swelling and pain.
  • Cabbage Leaves: Cooled, crushed green cabbage leaves can be placed inside the bra and are a traditional remedy for reducing engorgement discomfort.
  • Pain Relievers: Over-the-counter pain medications like ibuprofen can help manage pain and inflammation associated with engorgement.
  • Expressing for Comfort Only: To avoid stimulating further milk production, expressing or pumping should be minimized. However, if engorgement becomes unbearable, expressing just a small amount to relieve pressure can provide relief without encouraging more milk production.
  • Herbal Teas: Some sources mention herbal teas like sage or peppermint may help, though evidence is limited and consultation with a doctor is advised.

Risks, Precautions, and Contraindications

While Cabergoline is generally well-tolerated, it is not without risks and is not suitable for everyone. Key precautions and contraindications include:

  • Hypertensive Disorders: Cabergoline is contraindicated in patients with uncontrolled hypertension, pre-eclampsia, or postpartum hypertension due to the risk of serious adverse events.
  • Cardiovascular History: It should be used with caution in patients with a history of heart conditions.
  • Monitoring Blood Pressure: Blood pressure should be carefully monitored, especially during the first few days of treatment.
  • Psychiatric History: Women with a history of severe psychiatric disorders may be at higher risk for side effects.
  • Early vs. Established Lactation: Medication is most effective when taken soon after delivery to inhibit lactation. Once milk is established, it may still be effective but may be more complex to manage.

The Importance of Medical Consultation and Support

Every mother's experience after a stillbirth is unique, and the decision regarding lactation suppression is deeply personal. For some, medication offers a swift path to physical relief, while for others, non-pharmacological methods provide a gentler, more natural transition. The emotional toll of a stillbirth can be compounded by the physical discomfort of lactation, making open and honest communication with healthcare providers crucial. A doctor or midwife can provide a comprehensive review of risks and benefits based on a woman's medical history and guide her toward a decision that best suits her needs. Support groups, counselors, and resources like the Stillbirth and Neonatal Death Charity can also offer invaluable emotional support during this time.

Conclusion

In summary, Cabergoline is the primary medication prescribed to stop lactation after a stillbirth, working as a dopamine agonist to inhibit prolactin release. It is generally more effective and better tolerated than the older medication, Bromocriptine, which is associated with more serious risks. For those preferring or needing to avoid medication, non-pharmacological methods like breast support, cold compresses, and gradual milk expression for comfort are also viable options. Ultimately, a candid discussion with a healthcare provider is the most important step to ensure a safe and supportive journey through this challenging experience.

Frequently Asked Questions

Medications like Cabergoline are dopamine agonists, meaning they mimic the effects of dopamine. This inhibits the release of prolactin from the pituitary gland, which is the hormone responsible for milk production, thereby preventing or suppressing lactation.

Common side effects include dizziness, headache, nausea, and fatigue. More serious side effects, such as cardiovascular events, are rare but have been reported, especially in women with pre-existing conditions.

Yes. Cabergoline should be avoided in women with pre-eclampsia, uncontrolled hypertension, or a history of severe cardiovascular or psychiatric disorders. Close monitoring of blood pressure is necessary.

Yes, many women successfully manage lactation suppression with non-pharmacological methods. These include wearing a supportive bra, applying cold compresses, using cabbage leaves, and expressing milk only for comfort.

When Cabergoline is taken as directed by a healthcare professional soon after delivery, it can potentially prevent significant milk production from starting. If lactation is already established, the timeline for suppression can vary and should be discussed with a healthcare provider.

With natural methods, the process is more gradual. It can take anywhere from a few days to several weeks for the milk supply to dry up completely, depending on how established lactation was and the consistency of the methods used.

For mothers who express milk after stillbirth and wish to continue doing so for a time, milk donation is a possible option to be discussed with a healthcare provider and a human milk bank. Medication to suppress lactation is generally not compatible with continued milk production or donation.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.