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What Not To Do Before A General Anaesthetic: A Guide to Medications and Pharmacology

4 min read

Studies show that ignoring pre-operative instructions increases the risk of complications during general anaesthetic, particularly due to pulmonary aspiration of stomach contents. Knowing what not to do before a general anaesthetic, especially concerning medications and consumption, is vital for patient safety and a smooth recovery.

Quick Summary

This guide outlines crucial preparatory steps for patients undergoing a general anaesthetic, detailing the importance of adhering to fasting guidelines and restrictions on specific medications, supplements, alcohol, and nicotine to prevent dangerous drug interactions and serious complications like aspiration.

Key Points

  • Fast Completely Before Surgery: Do not eat solid food for 6-8 hours and only consume clear liquids for up to 2 hours before your arrival time to prevent dangerous pulmonary aspiration during anaesthesia.

  • Stop Specific Medications and Supplements: Cease taking blood-thinning medications (including NSAIDs and aspirin) and many herbal supplements weeks before surgery, as they can increase bleeding risk or interfere with anaesthetic drugs.

  • Disclose All Substance Use: Inform your anaesthetist about all substance use, including alcohol, nicotine, and recreational drugs, as these can impact the effectiveness and safety of anaesthesia.

  • Discuss Diabetes Medications: If you take diabetes medications like GLP-1 agonists (e.g., Ozempic), you must follow specific, customized fasting and medication instructions from your care team due to their effect on gastric emptying.

  • Remove Personal Items: On the day of surgery, remove all makeup, nail polish, jewelry, and piercings, as they can interfere with vital monitoring equipment.

  • Follow All Instructions: Adhere strictly to the pre-operative instructions given by your anaesthesia and surgical teams to avoid procedural delays or cancellations and minimize risks.

In This Article

Preparing for general anaesthesia is a critical process that ensures your safety during surgery. Your anaesthetist is responsible for your well-being throughout the procedure, and their ability to do so depends heavily on the information you provide and the instructions you follow. Failure to comply with these guidelines can lead to serious, life-threatening complications, potentially resulting in the delay or cancellation of your surgery. This guide addresses the most common things to avoid in the hours and days leading up to your anaesthetic.

Fasting: The Critical Rule

One of the most important pre-operative rules is to avoid eating or drinking. When you are under general anaesthesia, your body's protective reflexes, such as coughing and swallowing, are suppressed. Aspiration occurs when stomach contents enter the lungs, and an empty stomach is the best defense against this dangerous and potentially fatal complication.

Food and Liquids

The standard instruction is to have no solid food for a minimum of six to eight hours before surgery. For clear liquids, modern guidelines from the American Society of Anesthesiologists (ASA) often permit consumption up to two hours prior for healthy patients, though many facilities still follow a stricter timeline. Clear liquids include water, apple juice, black coffee, or tea without milk or cream. Individual circumstances and the time of the procedure will dictate the exact fasting schedule provided by your care team.

Special Dietary Considerations

For patients with diabetes or those taking certain medications like GLP-1 agonists (e.g., Ozempic, Wegovy), special instructions are necessary. These medications can slow gastric emptying, meaning the stomach may not be empty even after the standard fasting period, increasing aspiration risk. It is crucial to discuss these with your anaesthetist well in advance.

Medication Management Before Anaesthesia

Certain medications, both prescription and over-the-counter, can have dangerous interactions with anaesthetic agents or increase the risk of complications like bleeding. Your care team must have a complete and accurate list of everything you are taking.

Medications to Discontinue

  • Blood Thinners and NSAIDs: Drugs such as aspirin, warfarin (Coumadin), clopidogrel (Plavix), ibuprofen (Advil, Motrin), and naproxen (Aleve) interfere with blood clotting and must be stopped one to two weeks before surgery, depending on the specific medication.
  • Herbal Supplements and Vitamins: Many popular supplements, including ginseng, ginkgo biloba, St. John's Wort, vitamin E, and fish oils, can increase bleeding risk or interact with anaesthesia. These should typically be stopped one to two weeks before surgery.
  • Diabetes Medications: As mentioned, GLP-1 agonists and other diabetes medications must be discussed with your physician. They may need to be held for a specific period before surgery to prevent complications.

Medications to Continue

It is important to note that not all medications should be stopped. Some, like certain blood pressure medications (e.g., beta-blockers), may need to be taken with a small sip of water on the day of surgery. Your anaesthetist will provide precise instructions regarding which medications to continue and which to hold.

Substances to Avoid

Beyond prescribed and over-the-counter medications, other substances can profoundly impact your body's reaction to anaesthesia.

Alcohol

Consuming alcohol in the 24 to 48 hours before surgery is strongly discouraged. Alcohol can thin your blood, interfere with anaesthetic drugs, and increase dehydration. For chronic drinkers, withdrawal symptoms during or after surgery pose a significant risk, and a higher dose of anaesthesia may be required to achieve the desired effect.

Smoking and Nicotine

Ideally, you should stop smoking several weeks before surgery, but stopping at least 24 hours beforehand offers immediate benefits. Smoking compromises heart and lung function, increases the risk of blood clots, and impairs wound healing, making post-operative recovery more difficult.

Recreational Drugs

Use of recreational drugs must be disclosed to your anaesthetist. Stimulants like cocaine and methamphetamine can cause cardiac instability during surgery. Cannabinoids, including marijuana, can increase the need for anaesthetic and heighten pain perception after surgery. The effects of recreational drugs, combined with anaesthesia, can be toxic and potentially fatal.

Other Pre-Surgical Precautions

Your care team will provide a detailed checklist of things to avoid on the day of your surgery. These often include:

  • Makeup and Nail Polish: Remove all makeup, nail polish (especially from fingers), and lotions. These can interfere with monitoring devices that measure blood oxygen levels.
  • Jewelry and Piercings: Remove all jewelry and piercings to prevent infection and avoid potential burns from medical equipment like electrosurgical units.
  • Dental Appliances: Notify the anaesthetist of any loose teeth, dentures, or bridges, as these can pose a risk during intubation.

Comparing Safe vs. Prohibited Actions Before Anaesthesia

Activity Prohibited (Most Cases) Allowed (with Doctor's Approval)
Eating/Drinking Solid food, dairy products, non-clear liquids, alcohol within 6-8+ hours Clear liquids up to 2 hours before arrival
Medications Blood thinners (NSAIDs, aspirin, Plavix, Xarelto), many diabetes and weight-loss drugs Certain heart and blood pressure medications with a small sip of water
Supplements Ginseng, ginkgo, St. John's Wort, vitamin E, fish oil within 1-2 weeks Generally none unless explicitly approved by your anaesthetist
Lifestyle Smoking, vaping, alcohol consumption within 24+ hours None
Personal Items Makeup, nail polish, jewelry, body piercings None

Conclusion: The Importance of Communication and Compliance

Your personal health history, daily habits, and medication list are crucial pieces of information for your anaesthesia team. By following the prescribed instructions on what not to do before a general anaesthetic, particularly regarding medications and substances, you play an active and vital role in minimizing risks and ensuring a safe surgical experience. Always be completely transparent and do not hesitate to ask questions. Remember, these rules are in place for your safety.

For additional guidance and patient resources, consult authoritative sources like the American Society of Anesthesiologists (ASA).

Frequently Asked Questions

Eating or drinking before general anaesthesia is prohibited because the medications relax your body's protective reflexes, including swallowing. This increases the risk of pulmonary aspiration, where stomach contents enter the lungs, which can lead to serious complications or even death.

You should stop taking medications that can increase bleeding risk, such as blood thinners (e.g., warfarin, Eliquis, Plavix), NSAIDs (ibuprofen, naproxen, aspirin), and many herbal supplements (e.g., ginkgo, ginseng). It is essential to discuss your full medication list with your anaesthetist for specific guidance.

You should avoid drinking alcohol for at least 24-48 hours before surgery due to potential interactions with anaesthesia and dehydration. Smoking should be stopped as early as possible, but at a minimum, 24 hours before the procedure to reduce respiratory complications.

In many cases, modern guidelines allow for clear liquids up to two hours before your arrival time at the hospital. However, some institutions still enforce stricter rules. Always follow the specific instructions provided by your healthcare provider.

Removing nail polish, particularly from your fingers, allows anaesthesia providers to use a monitor called a pulse oximeter on your fingertip to accurately measure your blood oxygen saturation. Makeup, lotions, and jewelry can also interfere with monitoring or cause burns from medical equipment.

If you fail to follow the fasting instructions, your surgery may be delayed or cancelled. Depending on what and when you consumed it, the risk of aspiration is significantly increased, making the procedure unsafe.

Some blood pressure medications (like beta-blockers) are often continued and can be taken with a small sip of water on the day of surgery, while others (like ACE inhibitors) may need to be held. Your anaesthetist will provide clear instructions on which to take.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.