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What Not to Take When Having a Stroke: A Critical Guide to Medications and Pharmacology

4 min read

According to the Centers for Disease Control and Prevention, stroke is the fifth leading cause of death in the United States, and quick action is paramount for survival and recovery. Taking the wrong substance during a stroke can cause catastrophic harm, making it critical to know what not to take when having a stroke and to call 911 immediately.

Quick Summary

This guide outlines the critical medications and substances to avoid when a stroke is suspected, explaining the distinct dangers for ischemic and hemorrhagic strokes. It covers the risks of common drugs like aspirin, NSAIDs, and certain other medications, and emphasizes the importance of professional medical intervention over self-treatment. This is for informational purposes and not medical advice.

Key Points

  • Call 911 Immediately: Time is critical in stroke treatment, so immediate professional medical attention is the top priority.

  • Do Not Give Aspirin: Never give aspirin or other blood-thinning medications during a suspected stroke, as it could worsen a hemorrhagic stroke.

  • Avoid All Oral Intake: Do not give the person food, drink, or any medication by mouth due to the risk of impaired swallowing and aspiration.

  • NSAIDs Post-Stroke: Non-steroidal anti-inflammatory drugs like ibuprofen are often avoided after a stroke, especially hemorrhagic, due to the increased risk of bleeding.

  • Caution with Anticoagulants: The use of blood thinners must be carefully managed by a doctor, especially when restarting after a stroke or combining with other drugs.

  • Consult Professionals: All medication adjustments, including over-the-counter drugs, should be made with a healthcare provider's guidance.

  • Recognize Stroke Symptoms: Be aware of the FAST signs (Face drooping, Arm weakness, Speech difficulty, Time to call 911) to act quickly.

In This Article

Immediate Dangers: Why Self-Medication is Forbidden

When a stroke is suspected, the immediate and most crucial action is to call 911. Giving the person any medication, food, or drink is forbidden until a healthcare professional can assess the situation. The primary reason for this is the critical distinction between the two major types of stroke: ischemic and hemorrhagic. Roughly 87% of strokes are ischemic, caused by a blood clot blocking blood flow to the brain. In contrast, hemorrhagic strokes, caused by a ruptured blood vessel and bleeding in the brain, make up the remaining cases. Without a CT scan or MRI, there is no way to determine which type of stroke is occurring, and giving medication for the wrong type can have deadly consequences.

For example, if a hemorrhagic stroke is occurring, giving a blood-thinning medication like aspirin will worsen the bleeding, increasing the damage and potentially causing death. Furthermore, a stroke can impair a person's ability to swallow, and attempting to give anything by mouth could cause them to choke or aspirate. Emergency responders are equipped to provide the correct treatment based on a rapid medical assessment, so waiting for their arrival is the safest course of action.

The Critical Problem with Aspirin and Other Antiplatelets

Aspirin is a non-steroidal anti-inflammatory drug (NSAID) and an antiplatelet agent, meaning it helps prevent blood clots from forming. While a doctor may recommend daily aspirin for some people to prevent future strokes, it is extremely dangerous to take during an active stroke event. The possibility of the stroke being hemorrhagic means the risk of aggravating a brain bleed far outweighs the potential benefit for a clot-based stroke.

After a diagnostic scan confirms an ischemic stroke, a doctor may administer a powerful clot-busting drug like tissue plasminogen activator (tPA). This is a tightly controlled procedure, as tPA can also increase the risk of bleeding. The decision to administer it depends on the time since symptom onset and the patient's individual risk factors.

Medications to Avoid After a Stroke

After a stroke, a healthcare team will carefully manage medication to prevent a recurrence and address other health issues. Certain medications and classes of drugs require careful consideration, and some should be avoided entirely, particularly in the initial recovery period.

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Following a hemorrhagic stroke, NSAIDs like ibuprofen, naproxen, and even certain COX-2 inhibitors are generally avoided because they increase the risk of bleeding. Even after an ischemic stroke, NSAID use is often restricted, especially if combined with other antiplatelet drugs, due to the increased risk of gastrointestinal bleeding. While acetaminophen may be considered for mild pain, it is essential to consult a doctor before taking any over-the-counter pain reliever.

Anticoagulants (Blood Thinners)

For some patients with ischemic stroke (especially those with atrial fibrillation), anticoagulants like warfarin or direct oral anticoagulants (e.g., apixaban) are prescribed for long-term prevention. However, the timing of re-starting these medications after a stroke is a critical decision made by a neurologist, and the combination of anticoagulants and antiplatelet drugs should be avoided if possible. For those with a hemorrhagic stroke, anticoagulants are often stopped to prevent further bleeding.

Comparison of Medication Considerations by Stroke Type

Feature Ischemic Stroke Hemorrhagic Stroke
Emergency Medication (Pre-Hospital) DO NOT GIVE ANY MEDICATION. The type of stroke is unknown and aspirin could be deadly. DO NOT GIVE ANY MEDICATION. Giving blood thinners would worsen the brain bleed.
Aspirin Use Potentially helpful for some after diagnosis, but not safe to give before medical assessment. Contraindicated; would increase bleeding.
NSAID Pain Relievers Avoided initially; risk of gastrointestinal bleeding. Contraindicated due to high risk of bleeding.
Anticoagulants Started later for prevention in high-risk patients (e.g., atrial fibrillation). Often stopped to manage and prevent bleeding.
Narcotic Painkillers May be used for severe pain, but with caution due to sedation and cognitive impairment risk. Caution needed; sedation can further impair cognitive ability affected by stroke.

Other Problematic Substances

Several other substances and medications can pose a risk during or after a stroke:

  • Illicit Drugs: Stimulants like cocaine and amphetamines are known risk factors for stroke, as they can cause a sudden and severe increase in blood pressure.
  • Over-the-Counter Cold Preparations: Some nasal decongestants containing sympathomimetics (e.g., pseudoephedrine) may increase blood pressure and should be used with caution, if at all.
  • Excessive Alcohol: Heavy alcohol consumption increases the risk of both ischemic and hemorrhagic stroke. In the post-stroke period, it should be limited or avoided, especially for those on blood-thinning medications.

The Critical Role of Medical Professionals

Due to the complexities of stroke diagnosis and treatment, it is vital to trust medical professionals. Emergency medical services (EMS) are trained to assess stroke symptoms and transport patients to a stroke-ready hospital where a team of neurologists, neurosurgeons, and other specialists can act quickly. This may involve diagnostic imaging to determine the stroke type, followed by rapid administration of appropriate therapies.

For ongoing care, a doctor or pharmacist should be consulted about any and all medications, including over-the-counter drugs, supplements, and herbal remedies. They can help identify potentially dangerous drug interactions and adjust medication regimens to minimize risk and promote recovery. Never stop or change a prescribed medication without a healthcare provider's guidance, as this can be extremely dangerous. The American Heart Association provides a wealth of resources on stroke prevention and recovery, including medication management (www.stroke.org).

Conclusion: Prioritize Professional Intervention

In summary, the most important rule is to give absolutely nothing to a person suspected of having a stroke until directed by a medical professional. The potential for severe harm from self-medication, especially with common drugs like aspirin, is too great. Immediate action by calling 911 and providing the emergency team with as much information as possible, including the time of symptom onset, is the best course of action. Recovery from stroke is a complex process, and working closely with healthcare providers to manage medications is a crucial step towards preventing future events and ensuring the best possible outcome.

Frequently Asked Questions

It is dangerous to give a person aspirin during a stroke because it can't be determined whether the stroke is ischemic (caused by a clot) or hemorrhagic (caused by a bleed) without a medical scan. Giving aspirin, a blood thinner, during a hemorrhagic stroke will make the brain bleed worse and can be deadly.

The very first and most important thing to do is to call 911 immediately. Providing the emergency dispatcher with the time symptoms began is also critical, as it can influence treatment options.

No, you should not give the person any food, water, or other drink. A stroke can affect the ability to swallow, and attempting to give anything by mouth could cause choking or aspiration pneumonia.

While acetaminophen may be used for mild, non-stroke-related pain, non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen should be avoided. It is crucial to consult a doctor before taking any pain reliever post-stroke to ensure it is safe and does not interact with other prescribed medications.

Anticoagulants, or blood thinners, can increase bleeding. For a person who has had a hemorrhagic stroke (a brain bleed), these medications are often stopped to prevent further bleeding and allow the brain to heal.

Yes, drugs like cocaine and amphetamines significantly increase the risk of stroke by raising heart rate and blood pressure, which can damage blood vessels in the brain. Misusing prescription drugs can also be a risk factor.

The FAST acronym is a simple way to remember the signs of a stroke: Face drooping, Arm weakness, Speech difficulty, and Time to call 911.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.