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What's the difference between steroid and cortisone shots?

4 min read

In the United States, an estimated 68% of people seeking care for hip or knee osteoarthritis receive a corticosteroid injection [1.8.4]. But what's the difference between steroid and cortisone shots, two commonly used terms for this treatment?

Quick Summary

Clarifying a common point of confusion, cortisone is a specific type of corticosteroid, and 'cortisone shot' is a popular term for a corticosteroid injection, often called a 'steroid shot' [1.2.6, 1.2.3].

Key Points

  • No Real Difference: 'Steroid shot' and 'cortisone shot' both refer to corticosteroid injections used to reduce inflammation and pain [1.2.1].

  • How They Work: These injections deliver a concentrated dose of anti-inflammatory medication that mimics the body's natural hormone, cortisol, to a specific area [1.2.2].

  • Conditions Treated: They are commonly used for arthritis, tendonitis, bursitis, carpal tunnel syndrome, and back pain [1.3.4].

  • Duration of Relief: The effects can last from several weeks to a few months, depending on the individual and the condition being treated [1.6.4].

  • Limited Use Recommended: Due to risks like tendon weakening or cartilage damage, healthcare providers typically limit injections to 3-4 times per year in the same area [1.5.4, 1.6.4].

  • Not Anabolic Steroids: The corticosteroids in these shots are different from the anabolic steroids used for building muscle [1.2.6].

In This Article

Unraveling the Terminology: Steroid vs. Cortisone

When discussing anti-inflammatory injections for joint pain, the terms "steroid shot" and "cortisone shot" are often used interchangeably, and for good reason: there is essentially no difference [1.2.1]. A "cortisone shot" is a common name for a corticosteroid injection, and "steroid shot" is a broader term for the same treatment [1.2.2, 1.2.6]. Cortisone itself is a specific type of corticosteroid, a class of drugs that mimics the effects of cortisol, a hormone naturally produced by the adrenal glands to suppress inflammation [1.2.2, 1.4.5]. These therapeutic steroids are distinct from anabolic steroids, which are synthetic forms of testosterone used for muscle building [1.2.6].

What Are Corticosteroid Injections?

Corticosteroid injections deliver a powerful, manufactured anti-inflammatory medication directly to a specific area of inflammation in the body, such as a joint or tendon [1.2.4, 1.2.7]. By calming the immune system's response in that localized area, the injection effectively reduces swelling and alleviates pain [1.2.2, 1.7.1]. This targeted approach allows for a high concentration of the drug at the problem site with minimal systemic (full-body) effects [1.2.5]. While cortisone is a well-known corticosteroid, healthcare providers may use other types, including triamcinolone (Kenalog), methylprednisolone (Depo-Medrol), and betamethasone (Celestone) [1.4.2, 1.4.4, 1.7.4].

Conditions Treated

Providers use corticosteroid injections to manage a wide array of musculoskeletal conditions characterized by pain and inflammation. Common applications include:

  • Arthritis: Including osteoarthritis and inflammatory types like rheumatoid arthritis [1.3.6].
  • Tendonitis: Inflammation of a tendon, such as in the shoulder, knee, or elbow (tennis elbow) [1.3.1, 1.3.4].
  • Bursitis: Inflammation of the bursae, which are fluid-filled sacs that cushion joints [1.3.1].
  • Back and Neck Pain: Used for conditions like sciatica or pain from a herniated disc by injecting near the pinched nerve [1.3.1].
  • Nerve Entrapment Syndromes: Such as Carpal Tunnel Syndrome or Cubital Tunnel Syndrome [1.3.2].
  • Other Conditions: Including gout, plantar fasciitis, and certain autoimmune diseases [1.3.4, 1.3.6].

The Injection Procedure

A cortisone shot is a quick procedure typically performed in a doctor's office [1.7.4]. The provider will first clean the skin over the target area. They may apply a numbing spray to the skin [1.3.3]. The injection itself often contains a local anesthetic (like lidocaine) mixed with the corticosteroid [1.3.6]. This anesthetic provides immediate pain relief that lasts for a few hours, while the steroid medication typically takes several days—usually 5 to 7—to begin working and reduce inflammation [1.3.5, 1.6.3]. To ensure precise placement, especially for deeper joints like the hip or spine, the doctor may use ultrasound or X-ray (fluoroscopy) to guide the needle [1.7.1, 1.3.6].

Benefits, Risks, and Duration

The primary benefit of a steroid shot is potent, localized pain and inflammation relief, which can improve mobility and allow a patient to engage more effectively in physical therapy [1.3.2]. The duration of relief varies widely among individuals and depends on the condition being treated, lasting anywhere from a few weeks to several months or longer [1.6.2, 1.6.4].

However, there are risks and potential side effects:

  • Short-Term Effects: The most common issues include a temporary "cortisone flare" (a brief increase in pain and inflammation), pain or bruising at the injection site, facial flushing, insomnia, and a temporary rise in blood sugar levels, which is a key consideration for people with diabetes [1.5.1, 1.5.3].
  • Long-Term/Repeated Use Effects: Frequent injections in the same spot are generally discouraged as they can lead to more serious side effects, including weakening or rupture of tendons, cartilage damage, thinning of the skin, and loss of bone density [1.5.1, 1.5.4, 1.5.6]. Because of these risks, providers often limit the number of injections to about three per year in a single area and recommend waiting at least three months between injections [1.3.4, 1.6.4].

Terminology Comparison Table

Feature Steroid Shot (General Term) Cortisone Shot (Specific/Common Term)
Medication Class Corticosteroid [1.2.2] Corticosteroid [1.2.6]
Mechanism of Action Reduces inflammation by suppressing local immune response [1.2.2]. Reduces inflammation by suppressing local immune response [1.3.4].
Common Usage A broad medical term for any corticosteroid injection [1.2.4]. A widely used, popular term for a corticosteroid injection [1.2.5].
Specific Drug(s) Can be various types, e.g., Triamcinolone, Methylprednisolone [1.4.2]. Refers to injections containing a corticosteroid, which may be cortisone or other types [1.4.5].
Primary Purpose To treat localized pain and swelling from conditions like arthritis or tendonitis [1.3.1]. To treat localized pain and swelling from conditions like arthritis or tendonitis [1.3.6].

Conclusion

Ultimately, there is no functional difference between what people call a "steroid shot" and a "cortisone shot"—both refer to a corticosteroid injection aimed at relieving inflammation and pain [1.2.1]. The term "cortisone shot" has become a common shorthand for this effective and widely used treatment. While these injections can provide significant temporary relief and help facilitate rehabilitation, they are not a permanent cure for underlying conditions and must be used judiciously due to potential side effects from repeated use [1.3.3, 1.5.2].


For further reading, you may find information from the Cleveland Clinic useful: https://my.clevelandclinic.org/health/treatments/cortisone-shots-steroid-injections

Frequently Asked Questions

Yes, for practical purposes, they are the same. A 'cortisone shot' is a common term for a corticosteroid injection, often referred to more broadly as a 'steroid shot' [1.2.1, 1.2.6].

While any included local anesthetic provides immediate but temporary relief, the steroid medication itself typically begins to reduce inflammation and pain within a few days, often taking up to 5-7 days to take full effect [1.3.5].

The duration of pain relief varies but generally lasts from a few weeks to several months. Some people may experience relief for up to six months or longer, while for others it may be shorter [1.6.2, 1.6.6].

You may feel a sting or pressure when the needle is inserted, but the injection often includes a numbing agent to minimize discomfort. The area might be sore for a day or two afterward [1.5.5, 1.7.1].

Common, temporary side effects include pain at the injection site, facial flushing, difficulty sleeping, and a temporary increase in blood sugar levels. More serious side effects are rare but can occur with repeated injections [1.5.1, 1.5.3].

To minimize the risk of side effects like tendon or cartilage damage, most healthcare providers limit injections to no more than three or four times per year in the same location, with at least three months between shots [1.3.4, 1.6.4].

They are used to treat a variety of inflammatory conditions, including osteoarthritis, rheumatoid arthritis, bursitis, tendonitis, gout, carpal tunnel syndrome, and sciatica [1.3.1, 1.3.6].

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.