What is mupirocin cream used for?
Mupirocin cream is a topical antibiotic prescribed to treat bacterial skin infections caused by susceptible organisms, such as Staphylococcus aureus and Streptococcus pyogenes. It is approved for treating secondary infections associated with traumatic skin lesions, such as abrasions or small lacerations. Mupirocin works by inhibiting the bacteria's ability to produce the proteins they need to grow and multiply. The cream formulation is specifically indicated for infected wounds, distinguishing it from the ointment, which is commonly used for impetigo.
Before you begin treatment
Before applying mupirocin cream, it is important to take a few preparatory steps to ensure the medication is used safely and effectively. Always follow the specific instructions from your prescribing doctor, as the application frequency and duration may vary depending on your specific infection.
Here is what you need to do before application:
- Verify your prescription: Confirm you have the cream formulation of mupirocin, as there are different products for different uses (e.g., nasal ointment).
- Wash your hands: Always wash your hands thoroughly with soap and water both before and after handling the medication to prevent the spread of infection.
- Read the label: Review the medication label for any specific instructions or warnings from your pharmacist.
- Prepare the affected area: Gently clean the infected skin with mild soap and water, then pat it dry with a clean cloth. This removes any crust or debris that might prevent the cream from working effectively.
Step-by-step application guide
For proper and effective treatment, follow these steps every time you apply the cream:
- Wash and dry: Clean the affected skin area as instructed above, then wash your hands thoroughly.
- Apply a small amount: Squeeze a small amount of cream onto a clean fingertip, cotton swab, or gauze pad. A thin film is generally sufficient to cover the infected area.
- Rub in gently: Gently massage the cream into the infected area. It is important to cover the entire lesion completely.
- Cover if advised: If your healthcare provider has advised it, you may cover the treated area with a sterile gauze dressing. Do not use an airtight bandage unless specifically directed to do so, as this can trap moisture and worsen the infection.
- Wash hands again: Wash your hands again after application to prevent spreading the bacteria to other areas of your body or to other people.
Application frequency and duration
Mupirocin cream is typically applied as directed by a healthcare professional. It is crucial to use the medication for the entire prescribed course, even if your symptoms begin to clear up earlier. Stopping treatment prematurely can lead to a resurgence of the infection or contribute to the development of antibiotic resistance. If there is no clinical improvement within a few days of starting treatment, you should contact your doctor for re-evaluation.
Mupirocin cream vs. mupirocin ointment
While both mupirocin cream and ointment contain the same active ingredient, they are formulated differently and approved for different uses. The cream's water-miscible base is often perceived as less greasy and more patient-friendly than the ointment's polyethylene glycol base.
| Feature | Mupirocin Cream | Mupirocin Ointment |
|---|---|---|
| Indication | Secondarily infected traumatic skin lesions (cuts, abrasions) | Impetigo, nasal carriage of MRSA (using the specific nasal formulation) |
| Approved Age | Typically approved for children and adults | Typically approved for children and adults, with specific age guidance for impetigo |
| Vehicle | Water-miscible base | Polyethylene glycol-based base (standard ointment) |
| Precaution | Can be used on moderately or severely damaged skin as directed by a professional | Should be used with caution on large, damaged areas due to risk of polyethylene glycol absorption, especially with kidney problems |
Safety precautions and side effects
To minimize risks and potential adverse reactions, it is important to be aware of the following safety measures:
- External use only: Mupirocin cream is not for internal use. Avoid getting it in your eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse the area thoroughly with water.
- Local irritation: Some people may experience mild side effects like burning, stinging, itching, or redness at the application site. If these symptoms become severe, stop using the cream and contact your healthcare provider.
- Allergic reactions: Although rare, severe allergic reactions, including anaphylaxis (a potentially life-threatening reaction), can occur. Seek immediate medical attention if you experience symptoms like hives, swelling of the face or tongue, or difficulty breathing.
- Clostridium difficile diarrhea: Antibiotic-associated diarrhea can rarely occur, even with topical antibiotics like mupirocin. If you develop severe, watery diarrhea, especially weeks or months after treatment, contact your doctor immediately and do not take anti-diarrhea medication.
- Drug interactions: Do not mix mupirocin cream with other topical preparations, as this can decrease its effectiveness. Inform your doctor of all medications, supplements, and herbal products you are taking.
Conclusion
Following proper application techniques and safety guidelines is essential for the successful treatment of bacterial skin infections with mupirocin cream. Always remember to use the cream for the full duration prescribed by your doctor to prevent antibiotic resistance, even if your symptoms improve quickly. Adherence to these instructions will help you achieve the best therapeutic outcome while minimizing the risk of adverse effects. If you have any concerns or your condition does not improve, consult with your healthcare provider for further guidance. For more detailed prescribing information, you can consult sources like Drugs.com.
