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Can a steroid injection cause a headache?

4 min read

While not the most common side effect, headaches are a known possibility following a steroid injection. In one study involving nearly 1,700 people receiving injections for ankle issues, headaches were not reported, suggesting a low incidence for local joint procedures. However, a specific and distinct type of severe headache can occur after an epidural steroid injection.

Quick Summary

Headaches can be a side effect of a steroid injection, stemming from either the medication's systemic effects or, more rarely, a procedural complication like a post-dural puncture headache (PDPH) after an epidural. Symptoms and severity vary depending on the cause. Treatment options range from rest and hydration to specific medical procedures.

Key Points

  • Headaches are a known side effect: Although not the most frequent, headaches can occur after a steroid injection.

  • Two main types of headaches exist: One is a general, non-positional headache from the steroid's systemic effects, and the other is a severe, positional headache (PDPH) resulting from a rare complication of epidural injections.

  • Epidural injections carry a risk of PDPH: An accidental dural puncture during an epidural steroid injection can cause a leak of cerebrospinal fluid, resulting in a low-pressure headache that worsens when upright.

  • Management depends on the type of headache: Mild systemic headaches often respond to rest, hydration, and caffeine, while a persistent PDPH may necessitate an epidural blood patch.

  • Consult a doctor for severe symptoms: Severe or persistent headaches, particularly with additional symptoms like vision problems or weakness, warrant immediate medical attention.

In This Article

Understanding the Link Between Steroid Injections and Headaches

Steroid injections, also known as corticosteroid or cortisone shots, are powerful anti-inflammatory treatments used to manage pain and swelling in various joints and the spine. While effective for conditions like arthritis, back pain, and tendonitis, they can produce unwanted side effects, with a headache being one of the potential, though not inevitable, reactions. The mechanism behind the headache depends largely on the type and location of the injection.

Two primary pathways can lead to a headache following a steroid injection:

  • Systemic Side Effects: After an injection, the medication is absorbed into the body's circulation. This can cause a range of systemic effects, including insomnia, facial flushing, mood changes, and a temporary increase in blood sugar levels. Any of these systemic reactions can trigger a non-positional headache. The steroid's impact on blood pressure can also contribute. This type of headache is generally temporary, lasting anywhere from one to three days, and is a result of the body's adjustment to the medication.

  • Post-Dural Puncture Headache (PDPH): This is a specific and potentially more severe complication associated with epidural steroid injections (ESIs), which are administered into the space around the spinal cord. During the procedure, the needle can accidentally puncture the dura mater, the protective outer membrane surrounding the spinal cord. This can cause a leak of cerebrospinal fluid (CSF), leading to a drop in pressure around the brain. The result is a characteristic postural headache that worsens when sitting or standing and improves when lying down. Although considered rare, occurring in less than 1% of ESIs, the incidence can increase with larger needle sizes. A PDPH can sometimes manifest days after the procedure.

Comparing Headache Types from Steroid Injections

Feature Systemic Headache Post-Dural Puncture Headache (PDPH)
Cause Systemic absorption of the steroid medication and hormonal shifts. Accidental puncture of the spinal cord's protective membrane (dura mater) during an epidural injection, causing CSF leakage.
Associated Injection Type Common with any steroid injection (joint, muscle, epidural). Exclusively occurs after an epidural steroid injection.
Symptoms Non-positional head pain, possibly accompanied by insomnia, flushing, or mood swings. Distinctly positional head pain (worse when upright, better when lying down). May include neck pain, nausea, and light sensitivity.
Timing Typically within 1 to 3 days after the injection. Can start within 24 to 48 hours, but sometimes days later (up to 12 days reported).
Severity Usually mild to moderate; can feel like a tension headache or migraine. Can be severe and debilitating.

Managing Headache Symptoms

For mild headaches resulting from systemic effects, simple strategies can be effective:

  • Rest and Hydration: Lying down and ensuring adequate fluid intake can help alleviate discomfort.
  • Caffeine: Consuming caffeinated beverages like coffee or tea can provide relief, especially for headaches caused by low pressure.
  • Over-the-Counter Pain Relievers: Medications like acetaminophen can help manage the pain. Consult a doctor before taking NSAIDs like ibuprofen, especially if you have high blood pressure, as both can raise blood pressure.

For PDPH, the approach is more targeted and often requires medical intervention if symptoms are severe or persistent. Initial recommendations include rest, lying flat, fluids, and caffeine, but if the headache persists, a procedure called an epidural blood patch may be necessary. This involves injecting a small amount of the patient's own blood into the epidural space to seal the CSF leak.

When to Consult a Healthcare Provider

It is crucial to contact your doctor if a headache following a steroid injection is severe, lasts for more than a few days, or is accompanied by other concerning symptoms. These can include:

  • Vision changes or loss of vision
  • Tingling or numbness in the arms or legs
  • Dizziness or severe weakness
  • Fever or worsening swelling at the injection site
  • Seizures

While the prospect of a headache may be unsettling, it is important to remember that most steroid injections, particularly those into a joint, do not cause headaches. For epidural injections, while a PDPH is a documented risk, it is uncommon. The benefits of a steroid injection, especially for chronic and severe pain, often outweigh the manageable side effects. Being informed about the potential risks and understanding the different types of headaches that can occur allows for prompt and appropriate action if a headache does develop. Always discuss the risks and benefits of any procedure with your healthcare provider to make an informed decision.

Conclusion

To summarize, while a steroid injection can indeed cause a headache, it is a relatively uncommon side effect. The cause and severity of the headache depend on the injection type. Mild, non-positional headaches can arise from systemic steroid effects and typically resolve quickly with rest and over-the-counter pain relief. In the rare event of a post-dural puncture during an epidural injection, a severe, positional headache can occur, which may require specific medical treatment like an epidural blood patch. Patients should always be aware of the symptoms to watch for and seek medical advice for any persistent or severe headaches following a steroid injection, especially an epidural. Communicating with your doctor is key to balancing the benefits of pain relief with the risks of potential side effects.

Visit the Mayo Clinic for more information on managing cortisone shots.

Frequently Asked Questions

Yes, but the cause depends on the injection type. Joint or muscle injections can cause a systemic headache from the steroid entering the bloodstream, while epidural injections carry a small risk of a more severe post-dural puncture headache (PDPH).

A PDPH is a specific type of severe headache that can occur after an epidural steroid injection if the needle accidentally punctures the dura mater (the spinal cord's protective membrane), causing a CSF leak and a drop in pressure around the brain.

A PDPH is a distinctive postural headache that worsens significantly when sitting or standing and feels better when lying down. It may be accompanied by neck stiffness, nausea, or sensitivity to light.

A systemic headache from steroid absorption may start within a day or two. A PDPH can begin within 24 to 48 hours, but some cases have been reported to start days after the procedure.

For mild headaches, rest, hydration, and caffeine can help. If it is a PDPH and persists, a doctor may recommend an epidural blood patch procedure to seal the leak.

General headaches from systemic effects are possible but not among the most common side effects. The more severe PDPH is a rare complication of epidural steroid injections.

You should seek immediate medical attention for a severe or persistent headache, especially if it is accompanied by vision changes, numbness, severe weakness, seizures, or fever.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.