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Understanding the Connection: Can Steroid Injections Cause Headaches?

4 min read

According to research, headaches are a known side effect of corticosteroid injections, though their frequency can vary depending on the type of injection received. If you've been wondering, "Can steroid injections cause headaches?", the answer is yes, and understanding why is key to managing this potential side effect.

Quick Summary

Steroid injections can cause headaches through different mechanisms, including systemic side effects, insomnia, and temporary blood sugar fluctuations. Epidural injections carry a rare but serious risk of a post-dural puncture headache (PDPH) from a cerebrospinal fluid leak.

Key Points

  • Headaches can be a side effect: Steroid injections, both local and epidural, can potentially cause headaches, but the mechanism and severity can differ.

  • Epidural injections carry specific risks: A rare but distinct post-dural puncture headache (PDPH) can occur after an epidural injection due to a spinal fluid leak.

  • Identify the type of headache: PDPH is a positional headache (worse when upright), while systemic steroid-induced headaches are typically non-positional.

  • Other contributing factors: Steroids can cause insomnia and blood sugar fluctuations, which can also trigger headaches.

  • Contact a doctor for severe symptoms: Any severe positional headache, fever, or new neurological symptoms after an injection warrants immediate medical evaluation.

  • Rest and hydration are key for mild cases: For less severe, systemic headaches, simple measures like rest, fluids, and caffeine can provide relief.

In This Article

The Link Between Steroid Injections and Headaches

While steroid injections are highly effective at reducing inflammation and relieving localized pain, they are not without potential side effects. A throbbing head after a procedure might leave you asking, can steroid injections cause headaches? The answer is a definitive yes, with several possible culprits depending on the type of injection and individual patient factors. Understanding the different mechanisms can help you identify the cause and seek appropriate treatment.

Systemic Side Effects and Generalized Headaches

Even when injected locally into a joint, such as the knee or shoulder, some of the corticosteroid medication can be absorbed systemically into the bloodstream. This can lead to a range of side effects that affect the entire body. A temporary, generalized headache that is not positional (meaning it doesn't change with head position) is one such possibility. The steroid can also cause temporary insomnia or blood sugar fluctuations, both of which can trigger a headache. These types of headaches are generally short-lived and resolve on their own as the medication wears off.

Post-Dural Puncture Headache (PDPH) Following an Epidural

For those who receive an epidural steroid injection (ESI) for back or neck pain, a specific and more severe type of headache is a rare but possible complication. An ESI involves injecting the steroid into the epidural space, the area just outside the protective sac (dura) that surrounds the spinal cord. If the needle inadvertently punctures this sac, cerebrospinal fluid (CSF) can leak out. This fluid leak decreases the pressure around the brain, causing it to sag slightly when a person sits or stands, stretching surrounding nerves and causing a distinct positional headache.

Key characteristics of a PDPH include:

  • Positional pain: The headache is typically severe when sitting or standing and significantly improves or resolves when lying down.
  • Delayed onset: It may not appear immediately but can start anywhere from 24 to 48 hours, or even up to 12 days, after the procedure.
  • Other symptoms: Accompanying symptoms can include nausea, dizziness, sensitivity to light, and ringing in the ears.

Other Potential Contributors

Besides systemic effects and CSF leaks, other factors can cause or contribute to headaches after a steroid injection. For instance, increased blood pressure is a known side effect that can trigger headaches. While a less common cause, some individuals may also experience headaches as part of a more generalized nervous system response, leading to symptoms like flushing and sleeplessness.

Comparison of Headache Types After Steroid Injections

Feature Systemic Headache (Non-Positional) Post-Dural Puncture Headache (PDPH)
Cause Systemic absorption of the steroid, insomnia, or blood sugar fluctuations. Accidental puncture of the dura during an epidural injection, causing a cerebrospinal fluid (CSF) leak.
Timing Typically occurs within 1–5 days after the injection. Starts within 24–48 hours, but can be delayed up to 12 days.
Pain Characteristics Generalized, steady, or throbbing pain that is not dependent on body position. Severe pain when sitting or standing; relieved when lying down.
Associated Symptoms Facial flushing, sleeplessness, mood swings, increased appetite. Nausea, dizziness, sensitivity to light, ringing in the ears.
Treatment Rest, hydration, over-the-counter pain relievers. Rest, fluids, caffeine intake, and, in severe cases, an epidural blood patch.

What to Do If You Get a Headache

For a mild headache suspected to be from systemic steroid effects, home care is often sufficient. Ensure you are well-hydrated, get adequate rest, and use over-the-counter pain medication like acetaminophen, but consult your doctor before using NSAIDs like ibuprofen, especially if you have other health conditions.

If you have received an epidural injection and suspect a PDPH, contact your doctor immediately. They can advise on initial management steps, such as staying hydrated and drinking caffeinated beverages. For persistent or severe cases, a specialized procedure called an epidural blood patch may be required to seal the leak.

When to Seek Immediate Medical Care

While many side effects are benign, certain symptoms require immediate medical attention. Contact your healthcare provider or seek emergency care if you experience:

  • A severe headache that worsens when you sit or stand and improves when you lie down.
  • A fever of 101°F or higher.
  • Signs of infection at the injection site (increased swelling, redness, severe pain).
  • Sudden weakness, numbness, or tingling in your arms or legs.
  • Changes in vision or hearing.

Conclusion

While a headache is a known and potential side effect, most instances are mild and temporary. Severe, positional headaches, such as a post-dural puncture headache, are rare but can occur after epidural injections and require prompt medical attention. If you experience a headache following a steroid injection, monitor your symptoms and communicate with your healthcare provider to determine the appropriate course of action.

For more information on the side effects of cortisone shots, you can visit a trusted resource such as the Cleveland Clinic.

Frequently Asked Questions

Headaches are not the most common side effect of cortisone shots. One study of corticosteroid injections to the ankle reported no headaches, suggesting it's less common for joint injections. For epidural steroid injections, a post-dural puncture headache (PDPH) is uncommon, affecting less than 1% of patients, though incidence can vary depending on needle size.

A PDPH is characterized by a severe headache that worsens when sitting or standing and improves when you lie down. It can also be accompanied by nausea, dizziness, and visual or hearing changes.

A PDPH can start within 24 to 48 hours after the injection, but its onset can be delayed for up to 12 days.

Systemic headaches from cortisone shots are generally temporary, lasting only a few days. For PDPH, symptoms can resolve on their own within one to two weeks, but may require specific medical intervention.

Yes, insomnia is a known side effect of steroids and can contribute to or trigger a headache or migraine episode.

Initial treatments include rest, adequate hydration, and consuming caffeine. If the headache persists or is severe, a procedure called an epidural blood patch may be needed to seal the leak.

You should contact your doctor if you experience a severe positional headache, fever, intense pain, or worsening swelling at the injection site.

Yes, in some cases, steroid injections (like occipital nerve blocks) can be used to treat certain headache disorders, such as cluster headaches. However, this is a distinct use and does not negate the risk of a headache as a potential side effect in other situations.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.