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Does AUSTELL Tramadol Make You Sleep? Unpacking the Side Effects

4 min read

According to national surveys, approximately 1.6 to 1.8 million Americans have reported misusing oral tramadol [1.8.4]. A primary question for many users is, Does AUSTELL tramadol make you sleep? While it can cause drowsiness, its effect on sleep is complex and can even lead to insomnia [1.5.4].

Quick Summary

AUSTELL tramadol, a synthetic opioid, commonly causes drowsiness and sleepiness in users [1.2.1, 1.2.3]. However, this sedation may not lead to restorative sleep and can disrupt normal sleep cycles, sometimes causing insomnia [1.5.2, 1.5.4].

Key Points

  • Drowsiness is a Common Side Effect: Drowsiness and dizziness are among the most common side effects of tramadol, stemming from its sedative effects on the brain [1.2.1].

  • Paradoxical Insomnia: While tramadol can cause sleepiness, its long-term use is more associated with insomnia and disturbances to healthy sleep patterns [1.2.3, 1.5.4].

  • Disrupted Sleep Quality: Tramadol can disrupt sleep architecture by reducing the amount of restorative deep sleep and REM sleep, leaving users feeling tired even after sleeping [1.5.2].

  • Dosage Matters: The likelihood and severity of side effects, including sleepiness, generally increase with higher doses of tramadol [1.2.4].

  • Risk of CNS Depression: Combining tramadol with other central nervous system (CNS) depressants like alcohol or benzodiazepines significantly increases the risk of extreme sedation and respiratory depression [1.7.1, 1.7.2].

  • Avoid Driving: Due to the risk of drowsiness and impaired coordination, you should not drive or operate machinery until you know how tramadol affects you [1.2.3, 1.6.5].

  • Withdrawal Symptom: Insomnia is a common symptom experienced during withdrawal from tramadol as the brain's chemistry rebalances [1.5.1, 1.5.3].

In This Article

Understanding AUSTELL Tramadol and Its Purpose

Tramadol, marketed under various brand names including those by AUSTELL, is a synthetic opioid analgesic prescribed to manage moderate to severe pain [1.9.1, 1.9.2, 1.10.5]. It is often considered when other non-opioid pain relievers have proven ineffective [1.10.3]. Tramadol works through a dual mechanism: it acts as a weak µ-opioid receptor agonist and also inhibits the reuptake of serotonin and norepinephrine, two neurotransmitters involved in pain modulation [1.4.1, 1.4.5]. This complex action changes how the brain and nervous system respond to pain signals [1.10.1]. Due to its potential for misuse and dependence, tramadol is classified as a Schedule IV controlled substance in the United States [1.8.2, 1.9.4].

The Direct Answer: Does Tramadol Cause Sleepiness?

Drowsiness and sleepiness are among the most frequently reported side effects of tramadol [1.2.1, 1.2.4]. Studies show that a significant percentage of users experience these sedative effects, which are linked to the drug's action as a central nervous system (CNS) depressant [1.2.3, 1.2.4]. The likelihood of feeling sleepy can increase with higher doses [1.2.4]. For this reason, patients are strongly advised to avoid driving or operating heavy machinery until they understand how tramadol affects them [1.2.3, 1.6.5]. Combining tramadol with other CNS depressants, such as alcohol, benzodiazepines, or sleep aids, can dangerously amplify these effects, leading to profound sedation, respiratory depression, coma, and even death [1.7.1, 1.7.2].

The Paradox: Tramadol-Induced Insomnia

While tramadol can make you feel sleepy, it has a paradoxical relationship with sleep quality. Many users report that while the medication causes daytime drowsiness, it can disrupt nighttime sleep and even lead to insomnia [1.5.4]. This disruption occurs because tramadol can interfere with normal sleep architecture. Specifically, it can shorten the restorative stages of sleep, such as deep sleep (stage 4) and rapid eye movement (REM) sleep [1.2.3, 1.5.2]. REM sleep is crucial for memory consolidation, mood regulation, and feeling rested [1.5.2]. By reducing these vital sleep stages, tramadol-induced sedation does not equal healthy, restorative sleep. Over time, this lack of quality sleep can result in daytime fatigue, anxiety, and depression [1.5.2]. Furthermore, insomnia is a common symptom of tramadol withdrawal, as the brain readjusts to functioning without the drug's influence on neurotransmitters that regulate sleep-wake cycles [1.5.1, 1.5.3].

Comparison: Tramadol-Induced Drowsiness vs. Natural Sleep

It is crucial to distinguish between the sedation caused by tramadol and the natural sleep process. Sedation is a generalized slowing of the central nervous system, which may not cycle through the necessary sleep stages for physical and mental restoration [1.5.2].

Feature Tramadol-Induced Drowsiness Natural, Restorative Sleep
Sleep Architecture Often disrupts or shortens deep sleep and REM stages [1.5.2]. Follows a cyclical pattern of distinct stages (light, deep, REM) [1.5.2].
Feeling Upon Waking May still feel tired or groggy due to lack of quality sleep [1.5.2]. Typically feel refreshed and well-rested.
Daytime Impact Can cause excessive daytime sleepiness and impair cognitive function [1.5.1, 1.10.1]. Promotes daytime alertness and optimal functioning.
Underlying Mechanism A side effect of CNS depression caused by the medication [1.7.1]. A natural biological process regulated by the body's internal clock.

Managing Tramadol-Related Sleep Issues

If you are experiencing drowsiness or sleep disturbances while taking tramadol, several strategies can help manage these side effects. Many side effects, including drowsiness, may lessen or disappear within a week or two as your body adjusts to the medication [1.2.2].

To manage drowsiness:

  • Avoid Alcohol: Alcohol is also a CNS depressant and will worsen sleepiness and increase the risk of serious side effects [1.2.2, 1.7.1].
  • Use Caution: Avoid activities that require mental alertness, like driving, until you know how the medication affects you [1.6.5].
  • Talk to Your Doctor: If drowsiness is severe or persistent, your doctor might adjust your dose or suggest an alternative medication [1.2.2, 1.6.1].

To combat insomnia:

  • Establish a Routine: Stick to a consistent sleep schedule and create a relaxing bedtime routine, such as taking a warm bath or reading [1.5.3].
  • Optimize Your Environment: Ensure your bedroom is dark, quiet, and cool [1.5.3].
  • Avoid Stimulants: Avoid caffeine and nicotine, especially in the hours leading up to bedtime [1.5.3].

Conclusion

So, does AUSTELL tramadol make you sleep? The answer is a nuanced yes and no. It frequently causes drowsiness and sleepiness as a common side effect by depressing the central nervous system [1.2.1, 1.2.3]. However, this chemically induced sedation is not the same as restorative sleep. Long-term use or higher doses can disrupt sleep architecture, reduce vital REM and deep sleep stages, and paradoxically lead to insomnia [1.5.2, 1.5.4]. Anyone taking tramadol should be aware of its potent effects on both alertness and sleep quality and must avoid combining it with other depressants like alcohol [1.7.1]. Always consult a healthcare provider to manage side effects and ensure the safe use of this medication.


For more detailed information, consult the patient information provided by the U.S. Food and Drug Administration (FDA): https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020281s041lbl.pdf

Frequently Asked Questions

Yes, it's possible. In clinical studies, about 8% of people taking 100 mg of extended-release tramadol reported sleepiness, compared to just 2% of those taking a placebo [1.2.4]. However, effects can vary by individual.

For many people, drowsiness and other side effects may lessen or wear off within a week or two as their body gets used to the medication [1.2.2]. If it persists, you should consult your doctor.

Tramadol can do both. It commonly causes initial drowsiness and sleepiness [1.2.3]. However, it can also disrupt sleep patterns, particularly REM sleep, and lead to insomnia or a feeling of being awake at night [1.5.4].

No, it is not safe. Both alcohol and tramadol are central nervous system depressants. Combining them can lead to extreme drowsiness, dangerously slowed breathing (respiratory depression), coma, and even death [1.7.1].

Tramadol can cause insomnia by disrupting the natural sleep cycle, specifically by reducing the amount of deep sleep and REM sleep [1.5.2, 1.5.4]. It also affects neurotransmitters like serotonin and norepinephrine, which play a role in regulating sleep [1.4.1, 1.5.2].

No. The sedation caused by tramadol is not the same as natural, healthy sleep. It often fails to provide the restorative benefits because it can interfere with the brain cycling through the necessary sleep stages [1.5.2].

If you experience significant drowsiness, avoid driving or operating machinery. Do not drink alcohol, as it will make it worse. If the side effect persists or is bothersome, talk to your healthcare provider, who may adjust your dose or recommend a different medication [1.2.2, 1.6.1].

References

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  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.