Musely’s estrogen creams: Different formulas for different needs
Musely offers several compounded, prescription-strength topical creams that contain estrogen. However, the specific type and concentration of estrogen differ based on the product's intended purpose. Two of the most relevant products are 'The Estrogen Boost' for systemic menopause symptoms and 'The Aging Repair Cream' for facial rejuvenation. Since Musely is a telehealth provider using compounding pharmacies, the final formula is tailored to the patient and prescribed by a doctor after an online consultation.
Before using any Musely product containing estrogen, it is essential to consult with a healthcare provider. This information is for general knowledge and does not constitute medical advice.
The Estrogen Boost formulas for menopause
'The Estrogen Boost' is designed to help alleviate menopause symptoms such as hot flashes, night sweats, and sleep disturbances by increasing systemic estrogen levels. This product uses a combination of two bioidentical hormones: estriol and estradiol.
- Estriol (E3): This is a weaker form of estrogen, often used in topical treatments.
- Estradiol (E2): This is the most potent form of estrogen and a primary active ingredient in many hormone therapies.
Musely provides two main formulas for 'The Estrogen Boost':
- Duo Formula: Contains Estriol 0.4% and Estradiol 0.1%. This formula is for individuals without a uterus, as it does not include progesterone.
- Trio Formula: Contains Estriol 0.4%, Estradiol 0.1%, and Progesterone 20%. The addition of progesterone is often used for individuals with a uterus to help mitigate risks associated with estrogen-only therapy.
The Aging Repair Cream for facial rejuvenation
Musely's 'The Aging Repair Cream' is formulated specifically for the face to address signs of aging. This product uses estriol, a milder form of estrogen, which some believe can help plump the skin and improve elasticity.
- Aging Repair Cream Formula: Contains Estriol 0.3%, along with other skincare ingredients like Vitamin C and Hyaluronic Acid. The concentration is lower than the estriol used in 'The Estrogen Boost' and is intended for a localized effect on the skin rather than systemic absorption for menopausal symptoms.
Comparison of Musely Estrogen Creams
To clarify the differences in estrogen content, the following table compares Musely's main estrogen-containing products.
| Feature | The Estrogen Boost (Duo/Trio) | The Aging Repair Cream | Commercially Available HRT (e.g., Gels) |
|---|---|---|---|
| Primary Purpose | Alleviates systemic menopause symptoms (hot flashes, night sweats) | Addresses facial signs of aging (fine lines, skin elasticity) | Varies; treats systemic menopause symptoms |
| Estrogen Type | Bioidentical Estriol (0.4%) and Estradiol (0.1%) | Bioidentical Estriol (0.3%) | Typically Estradiol only, in varying strengths |
| Other Active Ingredients | Progesterone (in Trio formula) | Vitamin C, Hyaluronic Acid, Aloe | None or minimal |
| Prescription Required | Yes | Yes | Yes, for most estrogen-based products |
| Compounded | Yes | Yes | No, manufactured in standard formulations |
| Absorption | Intended for systemic absorption through the skin | Intended for localized, low-level skin absorption | Intended for systemic absorption through the skin |
Considerations and safety
While Musely's products are generally considered for use under the supervision of a healthcare provider, there are important safety considerations to keep in mind, particularly regarding estrogen.
Hormonal side effects: Since estrogen can be absorbed systemically even from topical applications, it can potentially cause hormonal side effects, such as breast tenderness or irregular bleeding. One social media user reported significantly elevated estrogen levels after using an estriol face cream, highlighting the importance of medical supervision.
Risk of complications: The risks associated with systemic estrogen, such as endometrial cancer, breast cancer, blood clots, stroke, and dementia, are well-documented. This is why the addition of progesterone in the Trio formula for women with a uterus is noted and why medical consultation is generally considered mandatory.
Patch testing: Musely recommends a patch test for new users, especially those with sensitive skin, to check for skin irritation, redness, or itching.
Conclusion
Understanding the estrogen content in Musely's compounded medications requires knowing that different products serve different purposes and contain varying concentrations of estrogen hormones. 'The Estrogen Boost' for menopause symptoms contains a combination of the more potent estradiol (0.1%) and the weaker estriol (0.4%), while 'The Aging Repair Cream' for facial aging uses a lower concentration of estriol (0.3%). As with any prescription hormone therapy, it is important to use these products under the guidance of a healthcare professional to ensure appropriate use and to manage any potential risks.
For more information on the use of topical estriol for cosmetic purposes, you can review expert commentary in the journal Practical Dermatology, which has covered Musely's product.
Disclaimer: Information provided is for general knowledge and is not a substitute for professional medical advice. Always consult with a healthcare provider before starting any new treatment or medication.
