Which is more effective, estriol or estradiol? Understanding Estrogen Therapy
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5 min read
Estradiol (E2) is considered the most potent of the three major endogenous estrogens, significantly influencing the reproductive system and systemic bodily functions, while estriol (E3) is its much weaker counterpart. Understanding the fundamental difference in potency and how they interact with the body is key to determining which is more effective, estriol or estradiol, for specific therapeutic applications like hormone replacement therapy (HRT).