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Is it better to take glycinate or citrate before bed?: A Pharmacological Look at Magnesium for Sleep

3 min read

An estimated 75% of U.S. adults do not meet the recommended daily intake of magnesium, a vital mineral for over 600 bodily functions. For those seeking to improve sleep, a common question arises: is it better to take glycinate or citrate before bed? The answer depends largely on your specific health goals.

Quick Summary

Magnesium glycinate is typically the superior choice for sleep due to its calming properties and gentle effect on the digestive system. Magnesium citrate is also highly bioavailable but is primarily used for constipation relief because of its strong laxative effect.

Key Points

  • Magnesium Glycinate is for Relaxation: Glycinate is the superior choice for promoting relaxation and improving sleep quality due to its calming effects on the nervous system.

  • Magnesium Citrate is for Constipation: Citrate is primarily used as a laxative and can cause stomach issues, making it a poor choice for consistent nighttime sleep support.

  • Gentle vs. Potent Digestive Effect: Glycinate is gentle on the stomach, whereas citrate's osmotic effect actively draws water into the bowels, causing a bowel movement.

  • High Bioavailability for Both: Both magnesium glycinate and citrate are considered to have high bioavailability, meaning they are well-absorbed by the body. The key difference lies in their side effects and intended purpose, not their absorption rate.

  • Timing Matters for Sleep: Taking magnesium glycinate before bed is a common recommendation to potentially aid sleep.

  • Consider Your Goal: Choose glycinate for sleep enhancement and citrate for digestive regularity, or speak with a doctor about a combined approach.

In This Article

The Foundation of Magnesium and Sleep

Magnesium, a crucial mineral, plays a central role in regulating the body's nervous system and promoting relaxation, two factors essential for a good night's sleep. The mineral accomplishes this through several mechanisms, including regulating GABA receptors, aiding muscle relaxation, supporting melatonin production, and reducing anxiety and stress.

Magnesium Glycinate: The Calming Sleep Aid

Magnesium glycinate, formed by binding magnesium to the amino acid glycine, is particularly beneficial for sleep. Glycine itself is an inhibitory neurotransmitter that enhances the calming effects. This form offers enhanced relaxation, high bioavailability, minimal digestive impact, and reduced anxiety. For those prioritizing sleep quality without digestive issues, glycinate is generally recommended for use before bed.

Magnesium Citrate: The Bowel Regulator

Magnesium citrate combines magnesium with citric acid and is known for its high bioavailability. However, its defining characteristic is its osmotic, or laxative, effect, which draws water into the bowels and can cause diarrhea. This form is primarily used for constipation relief and is generally not recommended before bed due to the potential for sleep disruption caused by its laxative effects. While it offers some muscle relaxation, its digestive impact makes it less suitable as a primary sleep aid.

Comparison Table: Glycinate vs. Citrate for Bedtime Use

Attribute Magnesium Glycinate Magnesium Citrate
Primary Purpose Relaxation, anxiety reduction, and sleep support Constipation relief and promoting bowel movements
Effect on Sleep Direct sleep enhancement through calming neural activity and relaxing muscles Secondary effect on relaxation; potentially disruptive due to laxative action
Digestive Impact Gentle on the stomach; low risk of gastrointestinal distress Significant laxative effect; high risk of stomach cramping and diarrhea
Bioavailability Very high High
Best for Bedtime Yes, excellent choice for promoting restful sleep Generally not recommended for sleep, unless constipation is the issue

How to Choose for Your Needs

The choice between magnesium glycinate and citrate depends on your goal. For sleep and relaxation, glycinate is the better choice due to its calming properties. For constipation relief, citrate is more appropriate due to its laxative effect, but it should not be taken right before bed. If addressing both concerns, a healthcare professional may suggest taking citrate earlier in the day and glycinate in the evening.

Important Considerations and Safety

When taking any magnesium supplement, adherence to usage guidelines is important to avoid side effects like nausea or diarrhea. Those with kidney issues or on certain medications should consult a doctor. Taking the supplement before sleep is often recommended for those seeking its calming effects. Safety measures include starting with a conservative amount, monitoring total intake, consulting a healthcare provider, and practicing good sleep hygiene.

Conclusion: The Best Choice is Based on Your Need

Both magnesium glycinate and citrate are well-absorbed but serve different purposes for bedtime use. For promoting restful sleep without digestive issues, magnesium glycinate is the better choice before bed due to its calming nature. Magnesium citrate is a strong laxative and is best for managing constipation. Understanding these differences helps in making an informed decision for your health and sleep goals. For more information on magnesium, refer to the National Institutes of Health fact sheet.

Frequently Asked Questions

You can, but it is not recommended if sleep is your only goal. Magnesium citrate is a strong laxative and can cause diarrhea and nighttime trips to the bathroom, disrupting your rest.

Magnesium glycinate works for sleep by calming the nervous system. The mineral itself helps regulate neurotransmitters like GABA, while the amino acid glycine adds to the relaxing effect, helping you fall asleep more easily.

The effects vary by individual, but many people report feeling more relaxed within a few hours. Taking it before bed is a common recommendation to align with the start of its calming effects.

The most common side effects of magnesium citrate are diarrhea, nausea, and abdominal cramping. These digestive issues can be disruptive and are counterproductive for a restful night.

Both magnesium glycinate and magnesium citrate are considered to have high bioavailability, meaning they are well-absorbed by the body. The key difference lies in their side effects and intended purpose, not their absorption rate.

Yes, some people strategically combine them, taking citrate earlier in the day for digestive health and glycinate at night for sleep. However, always consult with a healthcare professional to determine the appropriate use and timing for your needs.

Magnesium glycinate is often recommended for RLS because its muscle-relaxing properties may help alleviate the symptoms that interfere with sleep. However, more research is needed to confirm its effectiveness specifically for this condition.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.