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Is there an OTC version of azelastine? Understanding Astepro Allergy's Availability

4 min read

In 2021, the FDA approved the first-ever antihistamine nasal spray for nonprescription use, officially answering the question: is there an OTC version of azelastine? This approval made the active ingredient, azelastine, widely available over-the-counter for millions of allergy sufferers under the brand name Astepro Allergy.

Quick Summary

Astepro Allergy contains azelastine and is available over-the-counter for treating seasonal and year-round allergies. It's the first OTC nasal antihistamine and works quickly to provide relief, but it differs from nasal steroid sprays.

Key Points

  • OTC Availability Confirmed: Azelastine is available over-the-counter (OTC) under the brand name Astepro Allergy.

  • Astepro Allergy (0.15% strength): The specific OTC product contains a 0.15% strength of azelastine hydrochloride and was approved by the FDA in 2021.

  • Fast-Acting Relief: As a nasal antihistamine, Astepro works quickly—within 15 to 30 minutes—to relieve allergy symptoms, which is faster than many nasal steroids.

  • Drowsiness and Bitter Taste: Astepro can cause side effects like a bitter taste in the mouth and drowsiness, and caution should be used when driving or operating machinery.

  • Alternative to Steroids: Astepro offers a non-steroid alternative to products like Flonase, providing a different mechanism for allergy relief.

  • Rx vs. OTC Availability: Lower-strength azelastine (0.1%) remains prescription-only, and generic versions of the prescription product may offer lower costs.

In This Article

Yes, OTC Azelastine Is Available as Astepro Allergy

For many years, the direct-to-consumer question, is there an OTC version of azelastine?, was a simple 'no.' The antihistamine nasal spray was only accessible by prescription. However, that changed in 2021 when the Food and Drug Administration (FDA) approved a version for nonprescription use. This product is known as Astepro Allergy, and it contains the same active ingredient, azelastine hydrochloride, as its prescription counterparts. The OTC version is the 0.15% strength of azelastine hydrochloride nasal spray, which is approved for use in adults and children 6 years of age and older for the treatment of seasonal and perennial allergic rhinitis.

The move marked a significant shift in the landscape of over-the-counter allergy medications. While consumers previously had access to nasal steroid sprays (like Flonase) and oral antihistamines, Astepro Allergy was the first and only antihistamine nasal spray available without a prescription. This provides a new option for those who prefer targeted, nasal-specific antihistamine relief that acts much faster than oral tablets.

The Difference Between OTC and Prescription Azelastine

While Astepro Allergy makes azelastine accessible over-the-counter, a prescription version of the medication still exists and may be relevant for some users.

Prescription Azelastine:

  • Available in different strengths.
  • Can often be purchased as a lower-cost generic with a prescription.
  • Sometimes indicated for non-allergic nasal symptoms, a use not approved for the OTC product.
  • Certain strengths are not available over-the-counter.

OTC Astepro Allergy:

  • Contains a specific strength of azelastine hydrochloride.
  • Available directly from pharmacy shelves without a doctor's visit.
  • Can be a brand-name product, but generic options for OTC products may also exist.

For many, the convenience of purchasing Astepro Allergy without a prescription outweighs the potential cost savings of a generic prescription. However, those with ongoing or more severe allergy issues should consult a healthcare provider to determine the best treatment strategy and to explore all available options.

How Azelastine Compares to Other OTC Allergy Sprays

Azelastine is a nasal antihistamine, which works by blocking histamine receptors in the nose, a primary chemical responsible for allergic reactions. This is a different mechanism of action than corticosteroid nasal sprays, which target inflammation. Understanding these differences is crucial when choosing a medication.

Here's a comparison of Astepro Allergy with other popular OTC nasal allergy treatments:

Feature Astepro Allergy (Azelastine) Flonase (Fluticasone) / Nasacort (Triamcinolone) Oral Antihistamines (e.g., Zyrtec, Allegra) Nasal Decongestants (e.g., Afrin)
Drug Class Nasal Antihistamine Nasal Corticosteroid Oral Antihistamine Nasal Decongestant
Mechanism Blocks histamine receptors to prevent allergic reactions. Reduces inflammation in the nasal passages. Blocks histamine throughout the body. Constricts blood vessels to reduce swelling.
Onset of Action Fast, within 15-30 minutes. Slow, can take several days to reach full effect. Varies, typically within 1-3 hours. Fast, within minutes.
Primary Symptoms Treated Sneezing, itchy nose, runny nose, and nasal congestion. Nasal congestion, sneezing, runny nose, itchy nose. Sneezing, itching, watery eyes, and hives. Nasal congestion only.
Side Effects Bitter taste, nasal discomfort, drowsiness. Nosebleeds, nasal irritation, potential for slower growth in children with long-term use. Drowsiness (varies by product), dry mouth. Rebound congestion if used for more than 3 days.
Usage As directed by label or healthcare provider. As directed by label or healthcare provider. As directed by label or healthcare provider. Short-term use only (typically max 3 days).

Proper Usage and Potential Side Effects

Proper use of Astepro Allergy is essential for effectiveness and to minimize side effects. Users should shake the bottle gently before each use and follow the priming instructions for new or unused bottles. The correct technique involves spraying the medication into each nostril while avoiding spraying directly onto the nasal septum (the middle part of the nose). Always follow the specific instructions provided on the product packaging or by a healthcare professional.

Key considerations for using Astepro Allergy include:

  • Follow the age-specific instructions on the product label for the number of sprays and frequency of use.
  • Avoid exceeding the maximum recommended usage within a 24-hour period.
  • Avoid drinking alcohol or using other CNS depressants, as azelastine can cause drowsiness.

As with any medication, side effects can occur. The most common with azelastine include a bitter taste, nasal discomfort, and mild nosebleeds. Manufacturers have added sweeteners to help mask the bitter taste, but it may still be noticeable. Less common side effects can include headaches and drowsiness, so it's wise to understand how the medication affects you before driving or operating machinery.

Choosing the Right OTC Allergy Relief

Determining the best course of treatment for your allergies often depends on your specific symptoms and preferences. For those who experience primarily nasal symptoms and want fast relief, an antihistamine nasal spray like Astepro Allergy can be an excellent option. For others with more persistent inflammation, a nasal steroid like Flonase might be more effective in the long run. Combination therapy, such as using Astepro and Flonase together, is also an option that should be discussed with a healthcare professional.

Always read the product labels, follow the usage instructions carefully, and consult a pharmacist or doctor if you have questions or concerns about potential side effects or drug interactions. Choosing the right medication, whether it's a nasal spray, oral tablet, or a combination, can significantly improve your quality of life during allergy season.

Conclusion

In summary, the answer to the question is there an OTC version of azelastine? is a resounding yes, in the form of Astepro Allergy, a fast-acting nasal antihistamine. This option provides targeted relief for nasal allergy symptoms like sneezing, runny nose, and congestion, and is distinct from other over-the-counter options such as nasal steroids and oral antihistamines. Users should be aware of potential side effects, including a bitter taste and drowsiness, and follow usage instructions carefully. With the availability of OTC azelastine, consumers now have an expanded toolkit for managing their allergies effectively.

Authoritative outbound Markdown link: What You Need to Know About Astepro Nasal Spray - GoodRx

Frequently Asked Questions

The over-the-counter (OTC) brand name for azelastine is Astepro Allergy.

OTC Astepro is available in a 0.15% strength, while prescription azelastine is available in both 0.1% and 0.15% strengths. Generic azelastine is also typically only available with a prescription, which may be a lower-cost option.

No, azelastine is not a steroid. It is a nasal antihistamine that blocks the effects of histamine to relieve allergy symptoms, unlike corticosteroids such as fluticasone (Flonase).

Astepro Allergy can start providing relief from allergy symptoms within 15 to 30 minutes, making it a fast-acting option.

The over-the-counter version of Astepro Allergy is approved for use in adults and children aged 6 years and older.

Common side effects of Astepro Allergy include a bitter taste in the mouth, nasal discomfort, mild nosebleeds, headache, and drowsiness.

Yes, Astepro (a nasal antihistamine) and Flonase (a nasal corticosteroid) can be used together. They work via different mechanisms, and a doctor or pharmacist can advise if combination therapy is right for you.

Unlike nasal decongestants like Afrin, Astepro is not known to cause rebound congestion (worsening congestion) with prolonged or continuous use.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.