Tag: Anthraquinones

In 2002, the U.S. Food and Drug Administration (FDA) issued a final ruling that reclassified cascara sagrada, stating the ingredient was not "generally recognized as safe and effective" for over-the-counter use, effectively banning its sale in OTC laxatives. This decision was based on a lack of crucial safety data from manufacturers, not conclusive evidence of harm.

In May 2002, the U.S. Food and Drug Administration (FDA) issued a final rule removing cascara sagrada from the over-the-counter (OTC) drug market. This regulatory action prompted questions about the safety of the long-standing herbal remedy and why was Cascara sagrada banned from being sold as an OTC laxative. The decision highlights the rigorous standards required to prove a product is both safe and effective for public consumption, even for natural substances.