Tag: Endocannabinoid system

The sensation commonly described as a 'body high' is a complex physiological response, often associated with a feeling of deep relaxation and physical euphoria. Understanding the specific pharmacological pathways helps clarify what gives more of a body high, differentiating the effects of various substances that interact with the central nervous system to alter physical sensations.

Studies show that a significant percentage of patients seeking pain management explore cannabis-based options. As interest grows, many are asking: can Delta 9 be used for pain relief effectively and safely? This article examines the science behind Delta 9's role in pharmacology.

According to a 2021 CDC estimate, 51.6 million adults in the U.S. live with chronic pain, leading many to explore alternatives like THC variants. When considering **which delta is best for pain relief?**, it’s crucial to understand the distinct properties, potencies, and potential effects of Delta-8, Delta-9, and Delta-10 THC.

With the global CBD market projected to reach nearly $20 billion by 2025, more people are asking: what does a CBD high feel like? [1.8.1] Unlike its cousin THC, the experience is non-intoxicating, often described as a subtle sense of calm and relaxation [1.2.1].

In 2019, an estimated 50.2 million adults in the U.S. experienced chronic pain, with millions turning to opioids for relief [1.7.2, 1.7.3]. Amidst the opioid crisis, many are asking: Is CBD considered an opioid? The answer is a definitive no; they are pharmacologically distinct compounds [1.2.1].

A 2016 study published in a prominent pharmacology journal found that oral administration of cannabigerol (CBG) stimulated appetite in rats, significantly increasing their food intake without causing adverse neuromotor side effects. This discovery directly challenges the common, albeit unsubstantiated, claim that **is CBG an appetite suppressant** and instead positions it as a potential non-intoxicating appetite stimulant.

Delta 9 THC binds more strongly to the body's CB1 receptors than delta 10 THC, making it significantly more potent and responsible for the more intense 'high'. When asking what gets you higher, delta 9 or 10?, pharmacological evidence and anecdotal reports clearly indicate that delta 9 delivers a much stronger psychoactive effect.

Chronic pain affects millions of Americans, with the CDC reporting that over 51 million adults suffered from it in 2021. For those exploring alternatives, Delta 8 and Delta 9 THC offer potential pain relief by interacting with the body's endocannabinoid system, but understanding their distinct properties is crucial for effective pain management.

By 2024, an estimated 35% of all US citizens will have tried CBD [1.9.1]. A common question among new users is: can you get a buzz off CBD? The straightforward answer is no, as CBD is not intoxicating in the way THC is [1.2.5].

While the appetite-stimulating effect of THC is well-known, with research showing it activates specific hunger neurons in the brain, other cannabinoids have been found to have the opposite effect. This article explores which cannabinoid reduces appetite by examining how different cannabis compounds modulate the body's hunger signals through the endocannabinoid system.