Can LINZESS Cause Heartburn? Understanding the Connection
•
3 min read
In clinical trials for irritable bowel syndrome with constipation (IBS-C), gastroesophageal reflux disease (GERD), the chronic cause of heartburn, was reported as an uncommon side effect [1.5.1, 1.3.1]. This raises the question for many patients: **Can LINZESS cause heartburn** despite not being one of its most common side effects?