Tag: Manufacturing

Did you know that a single batch of medicine can contain millions of tablets, making batch-by-batch testing impractical? This is why understanding **what is GMP in pharmacology** is crucial, as it mandates a system of controls to ensure quality is built into every step of the manufacturing process, from raw materials to final product.

Developed by Japanese researchers in 1962, tranexamic acid is a synthetic drug created in a laboratory, not a naturally occurring substance found in plants or animals. Its source begins with a precursor molecule derived from the amino acid lysine.

According to the company, most Nature Made products are manufactured in the United States at their own facilities in Southern California and Alabama. While the finished products are primarily made domestically, this does not answer the question of where the raw ingredients are sourced, which is a common concern when asking, "Are Nature Made supplements made in China?".

According to data from IQVIA, the number of prescriptions for popular GLP-1 medications, like Zepbound and Wegovy, quadrupled over two years, creating unprecedented demand. This surge, combined with numerous supply chain and market factors, explains why many patients still find it so hard to get Zepbound at their local pharmacy.

Over 12% of US adults have used a GLP-1 drug, such as semaglutide, highlighting its widespread use. The complex process of how is semaglutide manufactured involves a multi-step journey, combining advanced biotechnology with precise chemical modifications to create a stable and effective therapeutic peptide.

The average cost to bring a new drug to market can range from under $1 billion to over $2 billion, a major factor contributing to **why is capsule so expensive**. The price tag is influenced by far more than just the physical shell, encompassing a web of factors from research to market exclusivity.

As of mid-2025, the U.S. is grappling with over 250 active drug shortages, a crisis impacting hundreds of thousands of patients [1.6.1, 1.6.3]. This raises a critical question for patients nationwide: why are pharmacies struggling to get medication?

With a history spanning over a century, the humble tablet press has evolved from a simple manual device into a sophisticated machine capable of high-speed, automated production. A tablet press is used for the critical process of compressing powdered or granulated materials into a solid, uniform tablet, ensuring consistent dosage and quality across millions of products.

Prior to the development of anti-D immune globulin in the 1960s, hemolytic disease of the fetus and newborn (HDFN) was a significant risk in Rh-incompatible pregnancies. This groundbreaking medication, widely known as RhoGAM, comes from a highly specialized process utilizing donated human plasma containing crucial anti-D antibodies.

With over 140 medical products in shortage as of mid-2024, the unavailability of Kenalog has become a significant concern for both patients and healthcare providers. Understanding **why is there a shortage of Kenalog** involves examining a complex web of manufacturing challenges, supply chain pressures, and shifting market dynamics.