Understanding Valtoco and Its Purpose
Valtoco® is a brand name for diazepam nasal spray, a prescription medicine used for the short-term treatment of seizure clusters, also known as acute repetitive seizures. It is not a daily anti-seizure medication but rather a 'rescue' therapy intended for immediate use when a person with epilepsy experiences a bout of frequent seizure activity that is different from their usual pattern. The active ingredient, diazepam, belongs to a class of drugs called benzodiazepines, which work by slowing down the central nervous system to calm abnormal overactivity in the brain. Because it is administered through the nose, it gets absorbed into the bloodstream quickly to stop a seizure episode, often within minutes. Valtoco is approved for use in adults and children two years of age and older.
Primary Feelings and Sensations from Valtoco
The primary goal of Valtoco is to stop seizure activity. The medication acts as a central nervous system (CNS) depressant. This action leads to several distinct feelings for the user. Because it enhances the effect of GABA, a natural calming chemical in the brain, a person will likely feel a sense of calm as the abnormal electrical activity subsides.
The most commonly reported feelings associated with Valtoco are sleepiness or drowsiness (somnolence), dizziness, reduced alertness, and a sense of calm. For many patients and caregivers, the most significant feeling is relief and a sense of regained control due to having an effective rescue medication available.
Common and Serious Side Effects
Beyond the intended calming and sedating effects, Valtoco has a range of potential side effects.
Common Side Effects (affecting at least 4% of users):
- Somnolence (sleepiness)
- Headache
- Nasal Discomfort (including irritation, altered taste, or runny nose)
Less Common but Possible Side Effects:
- Euphoria
- Loss of coordination (ataxia)
- Rash
- Diarrhea
Serious Adverse Reactions: Valtoco carries boxed warnings from the FDA for several serious risks. Serious effects can include central nervous system (CNS) depression, risks when combined with opioids and alcohol, abuse, misuse, addiction, dependence, withdrawal, and suicidal thoughts or behavior.
Comparison of Rescue Medications
Valtoco is one of several rescue medications available for seizure clusters. Understanding how it compares to others, like Nayzilam® (midazolam) and Diastat® (diazepam rectal gel), can be helpful.
| Feature | Valtoco® (diazepam) | Nayzilam® (midazolam) | Diastat® (diazepam) |
|---|---|---|---|
| Administration | Nasal Spray | Nasal Spray | Rectal Gel |
| Active Ingredient | Diazepam | Midazolam | Diazepam |
| Age Approval | 2 years and older | 12 years and older | 2 years and older |
| Common Side Effects | Sleepiness, headache, nasal discomfort | Sleepiness, headache, nasal discomfort, throat irritation | Sleepiness, headache, diarrhea |
| Dosing | Weight and age-based; single or double spray | Single 5 mg dose per spray | Weight-based; rectal syringe |
| Social Convenience | High; less invasive than rectal administration | High; similar to Valtoco | Lower; rectal administration can be socially difficult |
Conclusion
What Valtoco makes you feel like is primarily a state of calmness and significant sleepiness as it works to stop seizure activity in the brain. While common side effects include drowsiness, headache, and nasal discomfort, many users also feel relief and confidence in managing seizure clusters. However, as a potent benzodiazepine, Valtoco carries serious risks, such as dependence and dangerous interactions. It is crucial to use Valtoco exactly as prescribed and have a Seizure Action Plan discussed with a healthcare provider.
For more detailed information, consult the official VALTOCO® Prescribing Information.
