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What drugs are used for men's power? A Guide to Prescription Medications

4 min read

According to the American Academy of Family Physicians, at least 12 million U.S. men aged 40 to 79 experience erectile dysfunction (ED), a condition often tied to what people refer to as 'men's power'. Fortunately, safe, effective, and medically supervised treatments exist for this and other male sexual health concerns. This article details what drugs are used for men's power and performance, covering a range of scientifically-backed options available today.

Quick Summary

This guide explains the medical treatments for men's sexual health issues, including FDA-approved oral and injectable drugs for erectile dysfunction (ED), off-label antidepressant and topical therapies for premature ejaculation (PE), and hormone replacement for low testosterone.

Key Points

  • Variety of Treatments: Medications for 'men's power' address specific issues like erectile dysfunction, premature ejaculation, and low testosterone, each with different therapeutic approaches.

  • PDE5 Inhibitors for ED: The most common oral treatments for erectile dysfunction are PDE5 inhibitors, including sildenafil (Viagra), tadalafil (Cialis), and avanafil (Stendra), which increase blood flow to the penis.

  • PE Therapies: For premature ejaculation, options include topical numbing agents and off-label use of certain SSRI antidepressants or tramadol, which help delay climax.

  • Low T Treatment: Testosterone Replacement Therapy (TRT) is an option for men with clinically low testosterone levels and can improve libido and energy, but it requires a medical diagnosis.

  • Danger of Supplements: Unregulated 'male enhancement' supplements can be dangerous, often containing hidden prescription drug ingredients. Always stick to FDA-approved, prescription medications.

  • Consult a Doctor: It is critical to consult a healthcare provider for a proper diagnosis and to discuss potential risks, side effects, and drug interactions, particularly with heart medications.

In This Article

Addressing Men's "Power": A Medical Perspective

In casual conversation, the term "men's power" often refers to sexual performance, including the ability to achieve and maintain an erection, control ejaculation, and have a healthy libido. Medically, these are distinct issues with different pharmacological treatments. This guide focuses on the evidence-based, FDA-approved medications available by prescription, differentiating them from unproven or potentially dangerous over-the-counter supplements often marketed with misleading claims.

Oral Medications for Erectile Dysfunction (ED)

The most widely used pharmacological treatments for erectile dysfunction are phosphodiesterase-5 (PDE5) inhibitors. These drugs work by relaxing the muscles and widening the blood vessels in the penis, which helps increase blood flow during sexual stimulation, facilitating a firm erection. They do not cause an erection on their own; sexual arousal is still required.

Here are the most common PDE5 inhibitors:

  • Sildenafil (Viagra): Often the first line of treatment due to its long history and effectiveness. It typically takes effect in 30 to 60 minutes and lasts for about 4 to 5 hours. It is most effective when taken on an empty stomach. Generic sildenafil is significantly cheaper than the brand-name version.
  • Tadalafil (Cialis): Known for its long duration, lasting up to 36 hours in some cases, earning it the nickname "the weekend pill". It can be taken as needed or in a lower daily dose for more spontaneity. Unlike sildenafil, its absorption is not affected by food.
  • Avanafil (Stendra): A newer PDE5 inhibitor known for its fast onset, sometimes working in as little as 15 minutes. It has a lower risk of certain side effects compared to older medications.
  • Vardenafil (Levitra, Staxyn): Acts similarly to sildenafil, with effects lasting around 4 to 5 hours. It is available as a traditional tablet (Levitra) or a fast-dissolving tablet that can be placed under the tongue (Staxyn).

Treatments for Premature Ejaculation (PE)

For men who experience premature ejaculation, several medications can help delay climax, though some are used off-label.

  • Selective Serotonin Reuptake Inhibitors (SSRIs): A side effect of certain antidepressants is delayed orgasm, making them an effective treatment for PE. These include paroxetine, sertraline, and fluoxetine. The SSRI dapoxetine is specifically designed for PE and is available in some countries but not the U.S.. Treatment can be daily or on-demand.
  • Topical Anesthetic Agents: Creams or gels containing a numbing agent like lidocaine or prilocaine can reduce penile sensitivity and help delay ejaculation. They are applied 10 to 15 minutes before intercourse and can be purchased over-the-counter.
  • Phosphodiesterase-5 (PDE5) Inhibitors: Medications like sildenafil and tadalafil, while primarily for ED, can also be used in combination with SSRIs for PE, especially when ED is also a factor.
  • Tramadol: This opioid pain reliever also has side effects that can delay ejaculation and may be prescribed off-label when other options are ineffective.

Hormone Therapy for Low Testosterone

For men with clinically diagnosed low testosterone (hypogonadism) that contributes to symptoms like reduced libido, fatigue, and sometimes ED, Testosterone Replacement Therapy (TRT) may be prescribed. TRT is available in various forms, including injections, topical gels, patches, and pellets. It is important to note that TRT is only for men with confirmed low testosterone levels, as more is not necessarily better and can cause side effects. It is not a treatment for ED when testosterone levels are normal.

Comparison of Common Oral ED Medications

Feature Sildenafil (Viagra) Tadalafil (Cialis) Avanafil (Stendra)
Onset 30–60 minutes 30–45 minutes 15–30 minutes
Duration 4–5 hours Up to 36 hours 6–12 hours
Effect of Food Can be delayed by a fatty meal Not significantly affected Not significantly affected
Common Side Effects Headache, flushing, visual changes Headache, flushing, back/muscle pain Headache, flushing, back pain

Important Safety Precautions

Before starting any medication for sexual health, it is crucial to have a full medical evaluation by a healthcare provider. A doctor can determine the underlying cause of your symptoms and prescribe the safest, most effective treatment based on your overall health. Several key safety points to remember include:

  • Avoid Unregulated Supplements: Many products marketed as "male enhancement" pills are unregulated dietary supplements that may contain undisclosed prescription drugs and pose significant health risks. These are not FDA-approved and have not been proven safe or effective.
  • Drug Interactions: Combining ED medications with nitrates (often prescribed for chest pain or heart conditions) can cause a dangerous and potentially fatal drop in blood pressure. Always inform your doctor of all medications you take.
  • Serious Side Effects: While rare, some serious side effects require immediate medical attention. This includes priapism (a painful erection lasting more than four hours) and sudden loss of vision or hearing.

Conclusion

For men seeking to address concerns related to sexual health and performance, effective and safe pharmacological options are available under a doctor's care. What drugs are used for men's power depend on the specific condition, such as ED, PE, or low testosterone. Avoiding unproven supplements and seeking professional medical guidance is the most reliable path to finding a safe and effective treatment. A thorough evaluation can uncover underlying health issues and ensure the best course of action is taken, maximizing both safety and effectiveness.

Frequently Asked Questions

Both Viagra (sildenafil) and Cialis (tadalafil) are PDE5 inhibitors used for erectile dysfunction, but they differ primarily in duration. Viagra lasts for about 4 to 5 hours, while Cialis can last up to 36 hours. This makes Cialis a potential option for men who prefer not to time their medication around sexual activity.

No, most 'male enhancement' supplements are not regulated or proven safe. The FDA has issued multiple warnings about these products, which often contain hidden, undeclared ingredients, including prescription drugs, that can be harmful.

If you have heart disease, you must consult your doctor before taking any ED medication. PDE5 inhibitors, such as Viagra and Cialis, should never be taken with nitrates (medications for chest pain) due to the risk of a dangerous drop in blood pressure.

Drugs for premature ejaculation (PE) focus on delaying climax. Options include SSRI antidepressants, which delay orgasm, and topical anesthetic creams that reduce penile sensation. Unlike ED drugs, which increase blood flow, PE drugs work by different mechanisms and some are used off-label.

No. PDE5 inhibitors like Viagra and Cialis require sexual stimulation to work. They enhance the body's natural response to arousal by increasing blood flow to the penis, but they do not automatically trigger an erection.

TRT is prescribed for men diagnosed with clinically low testosterone (hypogonadism). Low T can cause reduced libido and energy. It is not intended for men with normal testosterone levels and is not a guaranteed cure for ED.

An erection lasting more than four hours (priapism) is a serious and rare medical emergency. If this occurs, seek immediate medical attention, as it can cause permanent damage.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.