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What is in Papilocare gel?

4 min read

According to a 2021 study, Papilocare vaginal gel was found to be effective in repairing low-grade cervical lesions in women infected with the human papillomavirus (HPV). This efficacy leads many to question: What is in Papilocare gel?

Quick Summary

Papilocare is a vaginal medical device containing a unique combination of natural ingredients, including extracts of Coriolus versicolor, Neem, and Aloe vera, plus the prebiotic BioEcolia. It also utilizes innovative niosome and phytosome technologies to deliver hyaluronic acid, beta-glucan, and Centella asiatica to the cervico-vaginal mucosa.

Key Points

  • Complex Natural Formula: Papilocare features a blend of seven hormone-free, natural ingredients, including plant extracts and a prebiotic, to address HPV-induced cervical lesions.

  • Innovative Delivery Systems: The gel uses advanced niosome and phytosome technologies to ensure key ingredients like hyaluronic acid, beta-glucan, and Centella asiatica are delivered effectively to deeper mucosal tissues.

  • Multi-Action Mechanism: The formula provides re-epithelializing, moisturizing, antioxidant, and prebiotic effects to repair mucosa, rebalance flora, and improve the epithelial barrier.

  • Key Active Components: Significant ingredients include the fungal extract Coriolus versicolor, Neem extract for healing, Aloe vera for moisture, and BioEcolia for supporting beneficial vaginal bacteria.

  • Protective Barrier Formation: Papilocare works by creating a defensive film over the cervical mucosa, which helps prevent the integration of the HPV virus and promotes a quicker healing process.

  • Hormone-Free and Well-Tolerated: The formulation is free from hormones, parabens, and fragrances, making it generally safe and well-tolerated for its intended use.

In This Article

Papilocare is a vaginal medical device designed to help manage and repair HPV-induced cervical lesions by forming a protective barrier and supporting the natural healing process. The product's innovative formulation distinguishes it from standard moisturizers by incorporating several key, naturally derived components, some delivered via advanced encapsulation technologies. Understanding the specific ingredients and their roles provides insight into how the gel works to address HPV-related issues and promote overall vaginal health.

Core Ingredients and Innovative Delivery Systems

Papilocare's composition is a sophisticated blend of extracts and encapsulated molecules, each chosen for its specific therapeutic properties. The primary components work in synergy to achieve the gel's documented effects.

Coriolus versicolor Extract

Derived from a medicinal mushroom known as the "Turkey Tail" fungus, Coriolus versicolor is a central ingredient. Its primary function in the gel is re-epithelializing and restoring the cervical-vaginal lesions and micro-lesions caused by HPV. It works to support tissue regeneration and accelerate the healing process in the affected area.

BioEcolia® (Alpha-oligoglycan)

This ingredient functions as a prebiotic that selectively stimulates the growth of beneficial bacterial flora, particularly Lactobacillus crispatus, which helps to rebalance the vaginal microbiota. Restoring a healthy microbial environment is crucial for protecting against infections and supporting the body's natural defenses.

Neem Extract (Azadirachta indica)

The extract from the Neem tree provides potent emollient properties. These properties help to soothe and lubricate the vaginal tissues, which is particularly beneficial for treating vaginal dryness and promoting the natural healing process of scarred or damaged mucosa.

Aloe vera Extract

A well-known soothing agent, Aloe vera provides moisturizing, re-epithelializing, and healing effects. It helps to keep the internal tissues hydrated and maintains their elasticity, contributing to overall comfort and tissue health.

Encapsulated Ingredients for Enhanced Delivery

Papilocare utilizes specialized delivery technologies to increase the bioavailability and effectiveness of certain ingredients.

  • Hyaluronic Acid Niosomes: Hyaluronic acid is a powerful humectant, meaning it attracts and retains moisture. By encapsulating it within niosomes, the gel ensures deeper hydration and elasticity for the mucosa, with a more prolonged and durable effect.
  • Beta-glucan Niosomes: Beta-glucans have both anti-inflammatory and antioxidant properties. Encapsulating them in niosomes helps maintain the natural structure and function of the skin and mucous membranes, while also improving the epithelial barrier function.
  • Centella asiatica Phytosomes: This botanical extract is known for its ability to promote tissue repair. Using phytosomal technology, the active ingredients of Centella asiatica penetrate more deeply into the basal layers of the epithelium, which stimulates collagen activation and helps regenerate mucosal lesions.

Excipients and Additives

Beyond its active components, the gel is also formulated with standard excipients to provide its gel-like texture and stability. These include water, propylene glycol, hydroxyethylcellulose, glycerin, and gel-forming agents. The product is hormone-free, paraben-free, and fragrance-free, making it suitable for sensitive vaginal environments. Potassium sorbate and sodium benzoate are used as preservatives.

Comparison: Papilocare Gel vs. Generic Vaginal Moisturizers

To highlight the unique composition and purpose of Papilocare, comparing it to generic vaginal moisturizers can be helpful.

Feature Papilocare Gel Generic Vaginal Moisturizer
Primary Use Prevention and treatment of HPV-induced cervical lesions; re-epithelialization. Addresses vaginal dryness and irritation for general comfort.
Key Active Ingredients Natural extracts: Coriolus versicolor, Neem, Centella asiatica, Aloe vera. Prebiotic: BioEcolia. Encapsulated: Hyaluronic acid, Beta-glucan. Typically focuses on moisturizing agents like hyaluronic acid or water-based gels.
Delivery Technology Advanced Niosome and Phytosome technologies for targeted and deeper penetration. Standard topical application, without specific encapsulation technology for deeper tissue delivery.
Action on HPV-related Lesions Scientifically demonstrated effect on repairing low-grade cervical lesions and enhancing viral clearance. No specific action on HPV lesions. Solely for symptomatic relief of dryness.
Action on Microbiota Contains BioEcolia, a prebiotic to rebalance the vaginal microbiota. No specific action on rebalancing the bacterial flora. May even disrupt it if not pH-balanced.
Hormone-Free Yes, it is a hormone-free formulation. May vary; some formulations may contain hormones or other synthetic compounds.
Compatibility Compatible with condoms. Compatibility may vary depending on the specific ingredients.

Conclusion

In summary, what is in Papilocare gel is a carefully engineered blend of natural ingredients, supported by advanced delivery technologies, for a multi-faceted therapeutic effect. Its composition, featuring potent extracts like Coriolus versicolor and Neem, encapsulated agents like hyaluronic acid and beta-glucan, and the prebiotic BioEcolia, allows it to go beyond simple moisturization. Instead, it actively contributes to the repair and re-epithelialization of cervical mucosa, helps rebalance the vaginal microbiota, and forms a protective barrier against HPV integration. This makes Papilocare a specialized medical device for addressing HPV-induced lesions, rather than a generic feminine hygiene product.

For more detailed clinical information on Papilocare's efficacy, you can refer to relevant studies published on the National Institutes of Health website.

Frequently Asked Questions

No, Papilocare is a Class IIa vaginal medical device, not a drug. It does not contain antibiotics or antiviral agents but rather works by helping to repair HPV-related lesions and supporting the body's natural healing processes.

It is generally recommended to pause the use of Papilocare during your menstrual period for comfort, as there is no clinical incompatibility. Treatment can be resumed after your period ends.

The duration of treatment is typically 6 months, though this can be extended based on a medical professional's advice and prescription.

Yes, Papilocare vaginal gel is compatible with the use of condoms, as it is a water-based formulation.

Papilocare is recommended for women over 18 years of age who are infected with HPV, whether or not they have corresponding low-grade lesions (ASCUS or LSIL).

No, Papilocare is a hormone-free and paraben-free formulation, designed to be highly tolerable and gentle on sensitive vaginal tissues.

BioEcolia acts as a prebiotic in the gel, stimulating the growth of beneficial bacteria within the cervico-vaginal area to help rebalance and restore a healthy vaginal microbiota.

By forming a protective film over the cervical mucosa, Papilocare creates a defensive barrier that reduces the risk of HPV integration into the cells, supporting the body's defenses.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.