What is Lofecam 8 used for?: Indications, Mechanism, and Side Effects

October 7, 2025 •

3 min read

According to studies, lornoxicam, the active ingredient in Lofecam 8, has demonstrated superior analgesic and anti-inflammatory effects compared to some other pain medications. This prescription-only medication is primarily used to relieve moderate-to-severe pain and inflammation associated with a range of conditions.

Quick Summary

Lofecam 8 is a prescription-only non-steroidal anti-inflammatory drug (NSAID) containing lornoxicam. It is prescribed for symptomatic relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and post-operative pain.

Key Points

Drug Class and Action: Lofecam 8 contains lornoxicam, an oxicam-class NSAID that inhibits cyclooxygenase enzymes (COX-1 and COX-2) to reduce pain and inflammation.
Primary Uses: It is prescribed for symptomatic relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute musculoskeletal disorders, and post-operative pain.
Taking the Medication: Lofecam 8 tablets should be swallowed whole before meals with a sufficient amount of liquid, as food can reduce its effectiveness.
Common Side Effects: Mild side effects include dizziness, headache, and stomach discomfort such as nausea, indigestion, and diarrhea.
Serious Risks: Potential serious side effects include gastrointestinal bleeding, kidney and liver problems, allergic reactions, and increased cardiovascular risk, particularly with long-term use.
Prescription Only: This medication is not available over-the-counter and requires a doctor's prescription due to its potent effects and potential risks.

What is Lofecam 8?

Lofecam 8 is a brand name for a prescription-only medication containing 8mg of lornoxicam, an NSAID of the oxicam class. It is used to reduce pain and inflammation.

How Lofecam 8 Works: Mechanism of Action

Lofecam 8 works by inhibiting cyclooxygenase (COX) enzymes, reducing the production of prostaglandins. Prostaglandins are chemicals involved in pain, fever, and inflammation. By blocking both COX-1 and COX-2 enzymes, Lofecam 8 helps alleviate inflammation symptoms, improving mobility and quality of life.

Primary Uses and Indications

Lofecam 8 provides symptomatic treatment for various inflammatory and painful conditions. The specific use of the medication is determined by a physician.

Inflammatory and Joint Conditions

Osteoarthritis: Manages pain and inflammation from cartilage breakdown.
Rheumatoid Arthritis: Relieves joint pain and swelling during flare-ups.
Ankylosing Spondylitis: Manages pain and inflammation during acute episodes.
Gout: Provides short-term pain management during flare-ups.

Post-operative and Other Acute Pain

Post-operative pain: Used for moderate to severe pain after surgery, with injectable forms for rapid action in hospitals.
Musculoskeletal pain: Relieves pain and inflammation in muscles and joints, including lower back pain and sprains.
Dental pain: Effective for pain after dental procedures.
Menstrual cramps: Can alleviate painful cramps.

Side Effects of Lofecam 8

Lofecam 8 can cause side effects ranging from common and mild to serious ones requiring medical attention.

Common Side Effects

Dizziness and headache
Nausea, vomiting, and diarrhea
Stomach pain, upset stomach, and indigestion

Serious Side Effects (Consult a doctor immediately)

Signs of gastrointestinal bleeding
Kidney or liver problems
Allergic reactions
Increased risk of cardiovascular events

Comparison of Lornoxicam (Lofecam 8) vs. Other Pain Relievers


Feature	Lofecam 8 (Lornoxicam)	Tramadol	Rofecoxib	Ibuprofen (Typical OTC NSAID)
Drug Class	Oxicam NSAID	Opioid Analgesic	Selective COX-2 NSAID	Propionic Acid NSAID
Mechanism	Non-selective COX-1 & COX-2 inhibition	Mu-opioid receptor agonist, inhibits serotonin/norepinephrine reuptake	Selective COX-2 inhibition	Non-selective COX-1 & COX-2 inhibition
Efficacy in Pain	Potent analgesic, shown superior to tramadol in some post-op pain	Effective for moderate to severe pain; potentially less effective for inflammatory pain	Effective but shown less potent than lornoxicam in some osteoarthritis studies	Effective for mild to moderate pain and inflammation
GI Tolerability	Improved profile over older NSAIDs due to shorter half-life; requires caution	Better GI profile than traditional NSAIDs; risk of dependency	Designed for better GI tolerability; some studies show mixed results	Common GI side effects; risk increased with high doses or prolonged use
Onset of Action	Typically within 30-60 minutes	Rapid onset, typically within an hour	Varies by formulation	Rapid onset, typically within 30 minutes to an hour

Important Precautions and Warnings

Inform your doctor of your medical history and medications before taking Lofecam 8.

Contraindications

History of peptic ulcers or GI bleeding
Severe heart, liver, or kidney failure
Bleeding disorders
Late-stage pregnancy
Breastfeeding
Children under 18

Precautions

Patients with asthma, heart failure, or hypertension require close monitoring.
Elderly patients may need careful consideration regarding the dose due to increased risk of adverse effects.
Avoid alcohol to reduce the risk of severe side effects like GI bleeding.

How to Take Lofecam 8

Administration: Swallow the tablet whole with liquid before meals. Do not chew, crush, or break it. Taking with food may reduce effectiveness.
Missed Dose: If a dose is missed, take it when remembered, unless it's near the next dose time. Do not double doses.

Conclusion

Lofecam 8, containing lornoxicam, is a potent prescription NSAID for managing pain and inflammation in conditions like arthritis and muscle disorders. It works by inhibiting prostaglandin synthesis. Due to potential side effects like GI and cardiovascular issues, its use requires a doctor's supervision. Patients must follow their doctor's instructions and report side effects immediately. It is an effective treatment for moderate to severe inflammatory pain when used appropriately under medical care. For more information, consult resources like PubMed articles on lornoxicam.

Lornoxicam, a new potent NSAID with an improved tolerability profile

Frequently Asked Questions

Yes, Lofecam 8 is a prescription medication that is not available over-the-counter. It must be prescribed by a registered medical practitioner.

It is not recommended to take Lofecam 8 with food, as food can reduce the medicine's effectiveness. The tablet should be taken before meals with an adequate amount of liquid.

Lofecam 8 (lornoxicam) typically starts working within 30 to 60 minutes, with peak effects occurring within a few hours.

You should not take Lofecam 8 if you are allergic to lornoxicam or other NSAIDs, have peptic ulcers, gastrointestinal bleeding, severe liver, kidney, or heart failure, or are in the last three months of pregnancy.

Long-term use of Lofecam 8 is generally not recommended unless directed by a doctor, as it increases the risk of serious complications like stomach bleeding and heart problems.

It is unsafe to consume alcohol with Lofecam 8, as it significantly increases the risk of severe adverse effects, particularly gastrointestinal bleeding.

No, Lofecam 8 is generally unsafe during pregnancy, especially in the last trimester, and is not recommended during breastfeeding. Always consult a doctor if you are pregnant or breastfeeding before use.

No, Lofecam 8 is an NSAID and is not a muscle relaxant. It works by relieving pain and inflammation, not by relaxing muscles.