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What is Maxilene cream? A comprehensive pharmacology guide

5 min read

Containing the local anesthetic lidocaine, Maxilene is a popular over-the-counter topical numbing cream used to alleviate the pain and itching from various minor skin irritations. The cream is designed to provide temporary, localized relief for conditions like minor burns, scrapes, and insect bites.

Quick Summary

Maxilene is a topical numbing cream with lidocaine as its active ingredient, available over-the-counter in certain concentrations. It works by blocking nerve signals to provide temporary relief from pain and itching for minor skin conditions and procedures.

Key Points

  • Lidocaine-Based Numbing: Maxilene is a topical anesthetic cream that uses lidocaine to provide temporary, localized numbing and pain relief.

  • Quick Onset: The cream typically begins to work within 20-30 minutes, faster than some other combination anesthetic creams.

  • Multiple Uses: It relieves pain from minor burns, scrapes, insect bites, and numbs the skin for injections, tattoos, and laser treatments.

  • Special Delivery System: Maxilene contains Accusomes™, microscopic spheres that help deliver the lidocaine directly to nerve endings.

  • Follow Application Rules: For safe use, apply as directed to clean, intact skin and never use it on open wounds or ingest it.

  • Watch for Side Effects: While generally safe, monitor for potential side effects like mild skin irritation or rare but serious issues like methemoglobinemia if overused.

In This Article

Understanding What is Maxilene Cream

Maxilene is a topical anesthetic cream formulated with lidocaine, a local anesthetic that creates a temporary loss of feeling in the skin and surrounding tissues. Available over-the-counter in various strengths, such as 4% and 5% lidocaine formulations, Maxilene is primarily used to relieve pain and itching associated with a wide range of minor skin ailments. This includes discomfort from minor burns, sunburn, cuts, scrapes, and insect bites. The cream's non-prescription availability in certain regions makes it a convenient option for managing localized pain at home.

How the Pharmacology of Maxilene Works

Maxilene's numbing effect is produced by its active ingredient, lidocaine. The mechanism is a straightforward and localized pharmacological action:

  • Active Ingredient: Maxilene contains lidocaine, an amide-type local anesthetic.
  • Mechanism of Action: Lidocaine works by blocking voltage-gated sodium channels in the nerve cell membranes. By doing so, it prevents the initiation and conduction of nerve impulses, effectively stopping the nerves from sending pain signals to the brain.
  • Delivery System: Maxilene cream features a delivery system that utilizes microscopic, multi-layered spheres known as Accusomes™. These spheres help transport the lidocaine directly to the nerve endings in the skin.
  • On-site Numbing: When the lidocaine reaches the nerve endings, it produces a cooling sensation followed by a numbing feeling in the applied area. The effect is localized, meaning only the covered skin will be affected.

This targeted mechanism allows Maxilene to provide rapid and effective temporary pain relief directly at the source of irritation.

Common Uses for Maxilene Cream

Maxilene is a versatile cream with several applications for minor topical pain management. Its primary uses fall into a few key categories:

For General Skin Irritations

Maxilene is well-known for its effectiveness in treating common, everyday skin ailments. These include:

  • Minor burns and sunburn: Soothing the burning sensation and pain from minor heat exposure.
  • Cuts, scrapes, and abrasions: Providing temporary relief from pain and discomfort associated with minor skin injuries.
  • Insect bites: Calming the itching and irritation caused by insect bites.
  • Minor skin irritations: Offering comfort for various other minor skin-related issues.

For Medical and Cosmetic Procedures

Beyond general use, Maxilene is also applied to numb the skin in preparation for minor procedures, reducing patient discomfort. These applications include:

  • Injections and blood draws: Easing the pain of needle insertions, such as those for vaccinations or blood sampling.
  • Minor dermatological surgeries: Numbing the treatment area for small skin procedures.
  • Cosmetic procedures: Reducing discomfort during procedures like laser hair removal, microdermabrasion, and tattooing.

For Anorectal Discomfort

Some formulations of Maxilene are specifically indicated for relieving the pain and itching related to anorectal disorders, such as hemorrhoids and general anorectal inflammation.

Proper Application of Maxilene Cream

For Maxilene to work effectively and safely, proper application is crucial. Here are some guidelines:

  1. Clean the Area: Gently clean the affected area with mild soap and water, and then pat it dry. Avoid using cleansers with alcohol or acetone, as they can interfere with the cream's absorption.
  2. Apply the Cream: Apply a thick layer of cream to the skin, ensuring the entire area to be numbed is covered. It is generally recommended not to rub it in completely.
  3. Occlusion (Optional): For a stronger effect, especially before a procedure, cover the cream with a clear plastic wrap or occlusive dressing. This is often recommended for 30 to 60 minutes prior to the procedure.
  4. Remove and Clean: Before the procedure or after the appropriate numbing time, wipe off any excess cream with a tissue or gauze.
  5. Wash Hands: Always wash your hands thoroughly with soap and water after applying the cream to avoid accidental exposure to other parts of the body.

Maxilene Cream vs. Other Topical Anesthetics

Maxilene is one of several topical anesthetic creams available. Its performance can be compared to others based on factors like onset time and duration of effect. For example, some anesthetic creams, like certain lidocaine-prilocaine mixtures, may take longer to achieve a numbing effect.

Feature Maxilene (Liposomal Lidocaine) Other Lidocaine/Prilocaine Creams (e.g., EMLA)
Active Ingredient Lidocaine Lidocaine and Prilocaine
Onset of Action Approximately 20-30 minutes Typically around 60 minutes
Application Apply thick layer, may or may not require occlusion Rub into the skin, typically requires occlusive dressing for a period
Primary Use Pain relief for minor irritations and some procedures Skin numbness for minor medical procedures
Formula Formulated with Accusomes™ for enhanced delivery Standard cream formulation
Availability Available over-the-counter in specific concentrations Both prescription and OTC options exist

Potential Side Effects and Safety Precautions

While generally safe for external use, Maxilene can cause side effects, especially if overused or applied incorrectly.

Common Side Effects:

  • Mild irritation, redness, or itching at the application site.
  • Temporary skin color changes.

Serious Side Effects (Rare):

  • Methemoglobinemia: A rare blood disorder where red blood cells can't carry oxygen effectively. Signs include bluish lips or skin, headache, unusual fatigue, or shortness of breath. This risk increases with high doses or improper use.
  • Allergic reactions: Hives, swelling, or difficulty breathing.
  • Signs of Overdose: Drowsiness, confusion, slow heart rate, or seizures if too much lidocaine is absorbed.

Precautions:

  • Use as Directed: Follow the product instructions carefully and do not exceed the recommended dosage or frequency.
  • External Use Only: Avoid contact with eyes, nose, mouth, and open wounds or damaged skin, as this can increase absorption and the risk of serious side effects.
  • Children: Consult a physician before using on children under two. For children aged 2 and older, use should be directed by a healthcare professional.

Conclusion

Maxilene cream, with its lidocaine-based formula, is a fast-acting topical anesthetic that provides temporary relief from pain and itching associated with minor skin irritations and certain cosmetic or medical procedures. Its specific Accusomes™ delivery system enhances its effectiveness by targeting nerve endings directly. While it offers a convenient and accessible solution for localized discomfort, users must adhere to proper application techniques and be aware of potential side effects, however rare they may be. Always consult a healthcare provider or pharmacist, especially for children or specific procedures, to ensure its safe and effective use.

Note: The availability and strength of Maxilene may vary by region. Always check local regulations and product labeling.

Frequently Asked Questions

The active ingredient in Maxilene cream is lidocaine, which is a type of local anesthetic used to numb the skin.

Maxilene typically begins to produce a numbing effect approximately 20 to 30 minutes after application, though this can vary.

Yes, Maxilene can be used to numb the skin and reduce discomfort associated with cosmetic procedures such as tattoos and laser hair removal.

Maxilene is generally not recommended for children under 2 years of age. For children 2 and older, it's best to consult a healthcare provider for proper guidance on usage.

No, Maxilene should only be applied to intact, undamaged skin. Applying it to open wounds or broken skin can lead to increased absorption of lidocaine and a higher risk of serious side effects.

Common side effects are mild and include temporary skin irritation, redness, or itching at the site of application.

Maxilene cream should be stored at room temperature, away from the reach of children. Make sure the container is tightly closed when not in use.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.