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What Is the Difference Between Voltaren and Voltaren Emulgel? A Comprehensive Guide

4 min read

Over 32 million adults in the U.S. have osteoarthritis, for which Voltaren is a common treatment option. However, many people are confused by the brand, which includes both oral medications and a topical gel. This guide will clarify the crucial difference between Voltaren and Voltaren Emulgel, explaining how their formulations dictate their use and potential side effects.

Quick Summary

Voltaren typically refers to oral diclofenac for systemic relief, while Voltaren Emulgel is a topical gel with specialized technology that delivers diclofenac locally to the site of pain. The Emulgel formulation allows for targeted action with significantly lower systemic absorption and risk of widespread side effects.

Key Points

  • Oral vs. Topical: The main difference is that Voltaren is an oral tablet for systemic pain, while Voltaren Emulgel is a topical gel for localized pain.

  • Diclofenac Salt: Oral Voltaren uses diclofenac sodium, whereas Voltaren Emulgel uses diclofenac diethylamine, which is optimized for skin penetration.

  • Enhanced Penetration: Voltaren Emulgel features a unique formulation that combines gel and cream properties, allowing the active ingredient to penetrate deep into the skin to the site of pain.

  • Side Effect Profile: The topical Emulgel formulation results in very low systemic absorption, significantly reducing the risk of widespread side effects associated with oral NSAIDs like gastrointestinal or cardiovascular issues.

  • Best Use Cases: Choose Voltaren Emulgel for targeted relief of localized pain (e.g., from osteoarthritis, sprains), and consider oral Voltaren for more widespread, systemic pain.

  • Consult a Professional: Always speak with a doctor or pharmacist to determine the best treatment option based on your medical history and specific pain needs.

In This Article

The brand name Voltaren is used for a variety of products containing the non-steroidal anti-inflammatory drug (NSAID) diclofenac, but it's the formulation that determines how the medication works. The most significant distinction is between the oral tablets (simply referred to as Voltaren) and the topical gel (Voltaren Emulgel). Choosing the correct product depends on the type of pain and potential risks.

The Systemic vs. Targeted Approach to Pain Relief

The fundamental difference between Voltaren oral tablets and Voltaren Emulgel lies in their method of delivery and the scope of their effect. Oral medication provides systemic relief, meaning the diclofenac travels through the bloodstream to affect the entire body. In contrast, the topical Emulgel offers targeted relief, focusing the active ingredient directly on the area of pain. This difference has major implications for efficacy, absorption, and side effects.

Oral Voltaren (Diclofenac Tablets)

Oral Voltaren contains diclofenac sodium, which is absorbed into the bloodstream through the digestive system. It is used for widespread or more systemic pain and inflammation from conditions such as rheumatoid arthritis, ankylosing spondylitis, or general pain. While effective, the systemic absorption can lead to a range of side effects, including gastrointestinal issues like stomach bleeding and ulcers, as well as cardiovascular risks, especially with long-term use.

Topical Voltaren Emulgel (Diclofenac Gel)

Voltaren Emulgel uses a specialized vehicle that combines a gel and a cream, designed to enhance the penetration of diclofenac through the skin. The active ingredient in this topical version is diclofenac diethylamine, which is formulated to be more readily absorbed transdermally. This technology creates a localized reservoir of diclofenac within the skin, which is then released slowly to the underlying tissue, joints, and muscles. Because only a small fraction of the drug is absorbed into the bloodstream, the risk of systemic side effects is significantly lower than with oral forms.

The Formulation: Diclofenac Salts and Penetration

The differences in formulation extend beyond the delivery method. The specific salt of diclofenac used is optimized for its intended route. Oral tablets contain diclofenac sodium, which is suited for dissolution and systemic absorption via the gut. Topical gels like Voltaren Emulgel contain diclofenac diethylamine, which is more effective for penetrating the skin barrier. The unique Emulgel formulation, which may include permeation enhancers like oleyl alcohol in higher-strength versions, further improves this process, ensuring more diclofenac reaches the targeted pain site. This shows that not all diclofenac formulations are the same, and the excipients play a crucial role in performance.

Key Differences at a Glance: Voltaren vs. Voltaren Emulgel

Feature Voltaren (Oral Tablets) Voltaren Emulgel (Topical Gel)
Application Method Taken orally (by mouth) Applied directly to the skin
Targeted Area Systemic (body-wide) pain and inflammation Localized pain in joints and muscles
Absorption High systemic absorption into the bloodstream Very low systemic absorption, primarily localized
Active Ingredient Salt Typically diclofenac sodium Diclofenac diethylamine
Side Effect Profile Higher risk of systemic side effects (GI, CV, renal) Lower risk of systemic side effects; primarily localized skin reactions (rash, irritation)
Best For Widespread pain (e.g., rheumatoid arthritis), migraine Osteoarthritis, sprains, strains, localized joint pain
Unique Feature Systemic effect via the bloodstream Enhanced skin penetration via Emulgel technology

Which is Right for You? Choosing Between Oral and Topical Treatment

Deciding between Voltaren oral and Voltaren Emulgel depends on your specific condition and medical history. Here's a guide to help you make an informed choice:

  • For localized pain: If you have pain limited to a specific area, like an arthritic knee, a sprained ankle, or a sore muscle, Voltaren Emulgel is often the better choice. Its targeted action delivers the medication directly to the source of pain, with a lower risk of the systemic side effects associated with oral NSAIDs. This is particularly beneficial for older adults or those with a history of stomach or heart problems.
  • For widespread pain: If your pain is widespread or systemic, such as with certain types of arthritis or migraine headaches, oral Voltaren may be more appropriate because it can relieve pain throughout the body. However, this comes with a greater risk of side effects, and it's essential to use the lowest effective dose for the shortest duration.
  • For safety considerations: Those with increased risk for gastrointestinal bleeding, heart issues, or kidney problems should consult a healthcare provider before using any NSAID. The topical route is generally safer from a systemic side effect perspective, but a doctor's advice is still crucial.
  • For application preference: Some people find topical gels easier to use, and some Voltaren Emulgel products even come with a hands-free applicator for convenience. However, the area of application can become irritated, dry, or red.

Conclusion: Targeted vs. Systemic Relief

The confusion between Voltaren and Voltaren Emulgel stems from the brand's use for both oral and topical diclofenac products. The crucial distinction is in the application and subsequent action. Voltaren oral tablets provide systemic, body-wide relief but with a greater risk of adverse effects. Voltaren Emulgel utilizes specialized technology for enhanced skin penetration, delivering diclofenac for targeted, localized relief with a better safety profile regarding systemic side effects. Always consult a healthcare provider to determine the most suitable option for your specific pain management needs.

Important Considerations

  • Voltaren oral tablets are typically reserved for more severe or widespread pain, under a doctor's supervision.
  • Voltaren Emulgel is an excellent choice for localized pain and is available over-the-counter for arthritis pain in many regions.
  • Even topical diclofenac carries some systemic risk, so caution is warranted, especially for individuals with underlying health conditions.
  • The specific salt of diclofenac (sodium vs. diethylamine) and the Emulgel formulation are what make the topical version different and more effective for localized relief.

Frequently Asked Questions

For localized pain and inflammation in specific joints or muscles, Voltaren Emulgel can be just as effective as oral Voltaren, but it works by delivering the medication directly to the site of the pain rather than through the bloodstream.

Yes, Voltaren Emulgel is generally considered safer regarding systemic side effects because very little diclofenac is absorbed into the bloodstream compared to oral tablets. This lowers the risk of gastrointestinal, cardiovascular, and renal complications.

While both contain the NSAID diclofenac, oral Voltaren typically uses diclofenac sodium. Voltaren Emulgel uses diclofenac diethylamine, a different salt formulated specifically for enhanced skin penetration.

Voltaren Emulgel is most effective for localized pain caused by conditions like osteoarthritis, sprains, strains, or muscle soreness. It is not designed for widespread pain or systemic conditions and should not be used for pain from sprains, strains, or sports injuries unless for osteoarthritis pain.

Yes, Voltaren Emulgel is available in different strengths, such as 1.16% and Extra Strength 2.32%. The Extra Strength version contains a higher concentration of diclofenac diethylamine and often includes permeation enhancers for deeper penetration.

You should not combine multiple NSAIDs, including oral and topical diclofenac, without a doctor's advice. Combining them increases your risk of side effects because both contribute to the overall NSAID load in your body, even if the topical absorption is low.

The most common side effects of Voltaren Emulgel are localized skin reactions at the application site, such as dryness, redness, rash, or itching. Systemic side effects are rare but possible with overuse.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.