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What is the gel for arthritis? A Complete Guide to Topical and Injected Gels

5 min read

Millions of adults experience the debilitating pain and stiffness of arthritis, yet localized treatment options can offer targeted relief. When people ask, "What is the gel for arthritis?" they are often referring to powerful topical anti-inflammatory gels like diclofenac or, in some cases, hyaluronic acid injections for specific joints.

Quick Summary

This guide details different gel options for arthritis, explaining how topical diclofenac targets pain and inflammation, while injected hyaluronic acid provides lubrication for joints.

Key Points

  • Diclofenac Gel (e.g., Voltaren): A topical NSAID that reduces localized inflammation and pain at the joint level.

  • Viscosupplementation: A procedure involving hyaluronic acid (HA) gel injections into larger joints, most notably the knee, to act as a lubricant and shock absorber.

  • Application Methods Differ: Topical gels are rubbed onto the skin, while viscosupplementation involves a series of injections administered by a doctor.

  • Treating at the Source: Topical diclofenac works by inhibiting pain-causing chemicals (prostaglandins), while HA injections replenish natural joint fluid.

  • Important Health Considerations: Patients with a history of heart disease, stomach issues, or certain allergies should consult a doctor before use.

  • Relief Varies: Topical gel effects may be felt over time with continuous use, while injected gels can take several weeks for full effect but may last for an extended period.

  • Always Consult a Doctor: Proper guidance from a healthcare provider is essential for determining the most appropriate and safest treatment for your specific arthritis condition.

In This Article

Before considering any medication, including gels for arthritis, it is essential to consult with a healthcare professional to determine the most appropriate treatment for your specific condition.

Understanding Arthritis Pain

Arthritis is an inflammatory condition that causes pain, swelling, and stiffness in the joints. It is a broad term that covers a range of conditions, with osteoarthritis (OA) and rheumatoid arthritis (RA) being the most common forms. While OA is caused by the wear-and-tear of cartilage over time, RA is an autoimmune disorder where the body's immune system attacks its own joints. For localized pain, topical treatments offer an alternative to oral medications, delivering the active ingredients directly to the site of pain.

Topical Gels: Diclofenac and Beyond

For many, the most accessible form of gel for arthritis is a topical Nonsteroidal Anti-inflammatory Drug (NSAID) containing diclofenac sodium. A common brand is Voltaren, which was previously prescription-only but is now available over-the-counter. Unlike oral NSAIDs that pass through the digestive system and affect the entire body, topical gels are applied directly to the skin over a painful joint.

How Diclofenac Gel Works

Diclofenac gel works by targeting the source of the pain: inflammation.

  • It contains the active ingredient diclofenac, a powerful NSAID.
  • The medication is designed to penetrate deep through the skin to the joint below.
  • It works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for producing prostaglandins—the chemicals that signal pain and inflammation.
  • By blocking these enzymes, the gel reduces inflammation, swelling, and pain right at the source, unlike many other topical pain relievers that only provide a cooling or heating sensation.

How to Properly Apply Topical Gel

Proper application is key to maximizing effectiveness and minimizing side effects. It is crucial to follow the specific instructions provided on the product label and any accompanying materials.

  • Read the label carefully and follow all directions.
  • Apply the gel to clean, dry, and unbroken skin over the affected joint.
  • Gently rub the gel into the skin.
  • Do not apply heat, bandages, or other dressings over the treated area unless directed by a healthcare professional.
  • Allow the treated area to dry before covering with clothing and before showering or bathing.
  • Wash your hands thoroughly after each application, unless the hands are the area being treated.

The Gel Injection: Viscosupplementation

For more severe cases of osteoarthritis, particularly in the knee, a doctor may recommend an injected gel treatment, also known as viscosupplementation or "gel shots".

What Are Hyaluronic Acid Injections?

  • The injected gel contains hyaluronic acid (HA), a naturally occurring substance found in the synovial fluid of healthy joints.
  • In patients with OA, the concentration of HA in the joint is lower than normal.
  • These injections replenish the joint's fluid, acting as a lubricant and shock absorber.
  • The procedure may involve a series of injections over several weeks, depending on the specific product used.

The Treatment Process

Hyaluronic acid injections are not a first-line treatment and are typically recommended after other methods have failed to provide relief. The process involves several steps:

  • The doctor will first determine if the patient meets the medical criteria for this treatment.
  • Prior to injection, other non-surgical options like physical therapy and oral NSAIDs are often tried for a period of time.
  • The procedure is performed in a clinical setting and is typically well-tolerated, though some temporary soreness or swelling can occur.
  • Relief is not immediate; it can take several weeks for the full benefit to be felt.

Comparing Arthritis Gels and Injections

Feature Topical NSAID Gel (e.g., Diclofenac) Viscosupplementation (e.g., Hyaluronic Acid)
Application Method Applied directly to the skin over the affected joint. Injected directly into the joint space by a medical professional.
Mechanism of Action Inhibits COX enzymes to reduce inflammation at the source. Supplements the joint's natural synovial fluid, acting as a lubricant and shock absorber.
Joints Treated Smaller, surface-level joints such as hands, wrists, elbows, feet, ankles, and knees. Primarily effective for larger joints, most commonly the knee.
Prescription Status OTC versions are available; higher concentrations may require a prescription. Always requires a prescription and is administered by a doctor.
Speed of Relief May take time with continuous use for significant relief. Can take several weeks for full effect, though relief may last for an extended period.
Side Effects Most common side effects are local skin irritation at the application site. Potential side effects include temporary pain, swelling, or warmth at the injection site.

Other Topical Alternatives

Besides diclofenac, other topical options can help manage arthritis pain, though they work differently:

  • Counter-irritants: Gels containing menthol (e.g., Biofreeze) or capsaicin (e.g., Zostrix) create a cooling or warming sensation that distracts from the deeper joint pain.
  • Natural supplements: Some gels or balms contain ingredients like arnica or other botanicals, though their effectiveness for arthritis is not as scientifically established as NSAID gels.

Important Safety Considerations

Before using any gel for arthritis, it is crucial to consult a healthcare professional. Although topical gels carry a lower risk of systemic side effects than oral NSAIDs, important precautions exist.

  • Heart and stomach health: People with a history of heart attack, heart failure, or gastrointestinal bleeding should exercise caution.
  • Pregnancy and breastfeeding: The use of diclofenac during pregnancy, especially after 20 weeks, is generally advised against.
  • Skin integrity: Never apply topical gels to broken, infected, or damaged skin.
  • Drug interactions: Inform your doctor and pharmacist of all medications you are taking, as topical NSAIDs can interact with blood thinners or other NSAIDs.
  • Allergies: Those with an aspirin allergy should not use diclofenac. People with bird allergies may need to avoid certain HA injections derived from rooster combs.

Conclusion: Choosing the Right Treatment Path

Choosing the right gel for arthritis depends on the severity and location of the pain, as well as individual health factors. Topical diclofenac gel offers targeted relief for superficial joints by reducing inflammation at the source. For persistent, localized pain in larger joints like the knee, a doctor may recommend viscosupplementation—injected hyaluronic acid that helps lubricate the joint. Regardless of the option, a consultation with a healthcare provider is the safest path to determining the most effective course of treatment. For further detailed information, consider reviewing reliable health resources such as the US National Library of Medicine's MedlinePlus drug information.

Frequently Asked Questions

The primary active ingredient in over-the-counter arthritis gel like Voltaren is diclofenac sodium, a topical nonsteroidal anti-inflammatory drug (NSAID).

A 'gel shot' is a common term for viscosupplementation, a procedure where a gel-like substance called hyaluronic acid is injected directly into a joint, most often the knee, to provide lubrication.

Diclofenac gel is primarily used for osteoarthritis, particularly in smaller, more superficial joints like the hands, wrists, elbows, knees, ankles, and feet. It may not be suitable for deep joints like the hip or back.

The most common side effect is skin irritation at the application site, such as redness, itching, or dryness. While less common, systemic side effects can occur, so it's important to discuss any concerns with a healthcare provider.

For nonprescription diclofenac gel, you may feel some relief within days, but it can take time with continuous, regular use to feel the full benefit.

It is generally not recommended to use a topical NSAID gel in combination with oral NSAIDs like ibuprofen or naproxen, as this can increase the risk of side effects. Always consult your doctor or pharmacist.

Relief from a hyaluronic acid injection is not immediate and may take several weeks to manifest. However, the pain relief can last for an extended period, sometimes several months or longer, for certain patients.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.